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Lipid droplets and polyunsaturated fatty acid trafficking: Balancing life and death
Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic turnover of biogenesis and breakdown to meet cellular requirements for fatty ...
Mauro Danielli +3 more
doaj +2 more sources
Summary Concerted alteration of immune and metabolic homeostasis underlies several inflammation-related pathologies, ranging from metabolic syndrome to infectious diseases.
Isabelle K Vila +2 more
exaly +2 more sources
Fatty Acid Desaturases, Polyunsaturated Fatty Acid Regulation, and Biotechnological Advances
Polyunsaturated fatty acids (PUFAs) are considered to be critical nutrients to regulate human health and development, and numerous fatty acid desaturases play key roles in synthesizing PUFAs.
Je Min Lee, Hyungjae Lee, SeokBeom Kang
exaly +2 more sources
Polyunsaturated fatty acids and inflammation [PDF]
The n-6 polyunsaturated fatty acid arachidonic acid gives rise to the eicosanoid family of inflammatory mediators (prostaglandins, leukotrienes and related metabolites) and through these regulates the activities of inflammatory cells, the production of ...
Calder Philip C.
doaj +5 more sources
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
Dietary polyunsaturated fatty acids (PUFA) are increasingly recognized for their health benefits, whereas a high production of endogenous fatty acids – a process called de novo lipogenesis (DNL) - is closely linked to metabolic diseases.
Anna Worthmann +29 more
doaj +4 more sources
Association between polyunsaturated fatty acid intake and proteinuria in the US adult population: a study from the NHANES database [PDF]
Background Moderate consumption of polyunsaturated fatty acids has been shown to confer a protective effect against proteinuria and to slow the progression of chronic kidney disease.
Hao Zhang, Qi Yu Zeng, Ping Zhang
doaj +2 more sources
Recent studies have clearly shown the importance of polyunsaturated fatty acids (as essential fatty acids) and their nutritional value for human health.
Elahe Abedi, Mohammad Ali Sahari
exaly +2 more sources
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids, and influence cellular function via effects on membrane properties, and also by acting as a precursor pool for lipid mediators.
S. Dyall +11 more
semanticscholar +1 more source
Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish.
Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA, C20-24), including eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3), are involved in numerous biological processes and have a range of health benefits.
Dizhi Xie +7 more
semanticscholar +1 more source

