Results 21 to 30 of about 65,432 (256)

Mast Cells, Astrocytes, Arachidonic Acid: Do They Play a Role in Depression?

Applied Sciences, 2020
Evidence support that brain membrane fatty acids play a crucial role in psychopathologies such as depression and anxiety disorders. Although the pathogenesis of depression is not still defined, drugs commonly used to reduce arachidonic turnover in the ...
Giovanna Traina, Massimo Cocchi
doaj   +1 more source

Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy

Cell & Bioscience, 2023
Objective Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare acquired immune-mediated neuropathy. Although microbial infection is potentially a contributing factor, a causative link between CIDP and microbial infection remains ...
Jiafang Fu, Jingli Shan, Yazhou Cui, Chuanzhu Yan, Qinzhou Wang, Jinxiang Han, Guangxiang Cao   +6 more
doaj   +1 more source

Polyunsaturated fatty acids and inflammation

Oléagineux, Corps gras, Lipides, 2004
The n-6 polyunsaturated fatty acid arachidonic acid gives rise to the eicosanoid family of inflammatory mediators (prostaglandins, leukotrienes and related metabolites) and through these regulates the activities of inflammatory cells, the production of ...
Calder Philip C.
doaj   +1 more source

Role of triglycerides in endothelial cell arachidonic acid metabolism.

Journal of Lipid Research, 1983
Arachidonic acid was incorporated into triglycerides by cultured bovine endothelial cells in a time- and concentration-dependent manner. At 75 microM or higher, more arachidonic acid was incorporated into triglycerides than into phospholipids.
G M Denning, P H Figard, T L Kaduce, A A Spector   +3 more
doaj   +1 more source

Uptake of long chain fatty acids by human placental choriocarcinoma (BeWo) cells: role of plasma membrane fatty acid-binding protein

Journal of Lipid Research, 1997
In order to understand the mechanisms by which fatty acids are taken up by the placenta, the uptake of oleic, linoleic, arachidonic, and docosahexaenoic acids by cultured human placental choriocarcinoma (BeWo) cells was examined.
F M Campbell, A M Clohessy, M J Gordon, K R Page, A K Dutta-Roy   +4 more
doaj   +1 more source

Dietary arachidonic acid increases deleterious effects of amyloid-β oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA2 balance

Alzheimer’s Research & Therapy, 2017
Background Polyunsaturated fatty acids play a crucial role in neuronal function, and the modification of these compounds in the brain could have an impact on neurodegenerative diseases such as Alzheimer’s disease.
Mélanie H. Thomas, Cédric Paris, Mylène Magnien, Julie Colin, Sandra Pelleïeux, Florence Coste, Marie-Christine Escanyé, Thierry Pillot, Jean-Luc Olivier   +8 more
doaj   +1 more source

Inhibition of the Nicotinic Ion Channel by Arachidonic Acid and Other Unsaturated Fatty, Acids in Chromaffin Cells from Bovine Adrenal Medulla

CHIMIA, 1991
The effects of arachidonic and other cis-unsaturated fatty acids were investigated in cultured chromaffin cells from bovine adrenal medulla with respect to Ca2+ influx and secretion of catecholamines.
Markus U. Ehrengruber, Peter Zahler
doaj   +2 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Metabolism of arachidonic acid-l-14C in the rat

Journal of Lipid Research, 1965
The metabolism of arachidonic acid-1-14C has been studied in the rat. The acid was fed as a component of randomly rearranged soybean oil; its absorption was greater than 96%.
Robert H. Coots
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source