Results 241 to 250 of about 966,330 (294)
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Hydroxyl radical formation by dithranol
Biochemical Pharmacology, 1988Ethene formation from 2-keto-thiomethyl-butyric acid (KMBA) was used to measure hydroxyl radical generation from the antipsoriatic drug dithranol in phosphate buffer pH 7.8. Because the singlet oxygen (1O2) sensitizer, rose bengale, showed enlarged production of ethene when irradiated in the presence of KMBA, experiments were performed in the dark in ...
K, Müller, H, Kappus
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The detection of hydroxyl radicals in vivo
Journal of Inorganic Biochemistry, 2008Several indirect methods have been developed for the detection and quantification of highly reactive oxygen species (hROS), which may exist either as free hydroxyl radicals, bound "crypto" radicals or Fe(IV)-oxo species, in vivo. This review discusses the strengths and weaknesses associated with those most commonly used, which determine the ...
W. Freinbichler +6 more
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Hydroxyl Radical Reactivity with Diethylhydroxylamine
Science, 1977Diethylhydroxylamine (DEHA) reacts with gas-phase hydroxyl radicals on every third collision, whereas the corresponding reaction in aqueous solution is considerably slower. The high gas-phase reactivity explains the predicted inhibitory effect of DEHA in atmospheric smog processes. Results from the studies in the aqueous phase are helpful in predicting
R A, Gorse, R R, Lii, B B, Saunders
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Reaction of dipyridamole with the hydroxyl radical
Lipids, 1992AbstractDipyridamole [2,6‐bis‐diethanolamino‐4,8‐dipiperidinopyrimido‐(5,4‐d) pyrimidine], a well known platelet aggregation inhibitor, shows powerful hydroxyl radical scavenging activity by inhibiting OH‐dependent salicylate and deoxyribose degradation.
IULIANO, Luigi +4 more
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Photogeneration of hydroxyl radicals for footprinting
Analytical Biochemistry, 1992Hydroxyl radicals yield footprints of DNA-ligand interactions that are uniform in intensity and display single base pair resolution. It is shown here that brief illumination of dilute aqueous solutions of hydrogen peroxide with a standard uv transilluminator can be used to generate hydroxyl radicals for footprinting studies.
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Hydroxylation of 3-nitrotyrosine by hydroxyl radical
Chinese Chemical Letters, 2007Abstract Hydroxylation of 3-nitrotyrosine (3-NT) and 3-NT containing peptide Gly-nitroTyr-Gly in aqueous solution by hydroxyl radical were investigated with gamma irradiation. The structures of the hydroxylated products were confirmed by electrospray ionization mass spectrometry and 1 H NMR spectrometry.
Jun Chen Dong +3 more
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Reactions of the Hydroxyl Radical with Polynucleotides
Radiation Research, 1973MICHAELS, H. B., AND HUNT, J. W. Reactions of the Hydroxyl Radical with Polynucleotides. Radiat. Res. 56, 57-70 (1973). Reactions of the hydroxyl radical with various monomeric components of nucleic acid, and with polynucleotides, were studied by observing the transient absorption of the -OH adduct species.
H B, Michaels, J W, Hunt
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DNA footprinting with hydroxyl radical
Nature, 1988High resolution images of proteins bound to DNA can be achieved through the use of a simple inorganic chemical system that produces the hydroxyl radical.
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Analytical Biochemistry, 2001
Hydroxylation of l-phenylalanine (Phe) by hydroxyl radical (*OH) yields 4-, 3-, and 2-hydroxyl-Phe (para-, meta-, and ortho-tyrosine, respectively). Phe derivative measurements have been employed to detect *OH formation in cells and tissues, however, the specificity of this assay is limited since Phe derivatives also arise from intracellular Phe ...
BIONDI, Roberto +5 more
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Hydroxylation of l-phenylalanine (Phe) by hydroxyl radical (*OH) yields 4-, 3-, and 2-hydroxyl-Phe (para-, meta-, and ortho-tyrosine, respectively). Phe derivative measurements have been employed to detect *OH formation in cells and tissues, however, the specificity of this assay is limited since Phe derivatives also arise from intracellular Phe ...
BIONDI, Roberto +5 more
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Isotopic Spectra of the Hydroxyl Radical
The Journal of Physical Chemistry A, 2013Rotational spectra of OH and its isotopologues have been precisely measured using high efficiency terahertz (THz) sources. The measurements are compared with existing data and are useful for global modeling. For the first time, microwave measurements of the Λ-doubling transitions of the (17)OH isotopologue are combined with THz data successfully ...
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