Comparative Evaluation of the Radical-Scavenging Activities of Fucoxanthin and Its Stereoisomers
Molecules, 2014 Fucoxanthin (Fuco) is a characteristic carotenoid of brown seaweeds. In the present study, Fuco and its stereoisomers 9'Z-Fuco, 13Z- and 13'Z-Fuco were extracted from Laminaria japonica Aresch.
Yiping Zhang +7 more
doaj +1 more source
Inhibitory Effect and Mechanism of Scutellarein on Melanogenesis
Cosmetics, 2021 Fairer skin is preferred in many Asian countries and there is a high demand for skin whitening and lightening products. However, in recent years, problems related to the safety of using whitening agents have emerged.
Liyun Dai, Lihao Gu, Kazuhisa Maeda
doaj +1 more source
Developmental stage is an important factor that determines the antioxidant responses of young and old grapevine leaves under UV irradiation in a green-house. [PDF]
, 2011 The impact of UV irradiation was studied on photosynthesis, photosystem II photochemical yields and antioxidant responses using green-house grown grapevine (Vitis vinifera L. cv. Chardonnay) leaves.
Hideg, Éva, Majer, Petra
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Journal of Pharmacological Sciences, 2007 Recent findings have suggested that the N-methyl-D-aspartate (NMDA) receptor-dependent hydroxyl radical pathway in the hypothalamus of rabbit brain may mediate the fever induced by lipopolysaccharide (LPS).
Ting-Yu Kao +3 more
doaj +1 more source
The Photochemistry of Nitrous Acid in an Aqueous Matrix [PDF]
, 2003 The thermal and photochemical decomposition of aqueous solutions of nitrous acid and nitrite ion were studied, with a focus on the production and subsequent reaction of hydroxyl radicals.
Ratliff \u2703, Jay S.
core +1 more source
Phenolic content of Hypodaphnis Zenkeri and its antioxidant effects against fenton reactions’ mediated oxidative injuries on liver homogenate [PDF]
, 2014 Under oxidative stress conditions, endogenous antioxidant defenses are unable to completely inactivate the free radicals generated by an excessive production of reactive oxygen species (ROS).
Biapa +14 more
core +3 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Development of Container Free Sample Exposure for Synchrotron X-ray Footprinting. [PDF]
, 2020 The method of X-ray footprinting and mass spectrometry (XFMS) on large protein assemblies and membrane protein samples requires high flux density to overcome the hydroxyl radical scavenging reactions produced by the buffer constituents and the total ...
Chen, Yan +4 more
core +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source