Results 71 to 80 of about 38,212 (261)
MoleculesAmines and hydroxylamines are essential compounds in the synthesis of pharmaceuticals and other functionalized molecules. However, the synthesis of primary amines and particularly hydroxylamines remains a challenging task.
Elena Redina +5 more
doaj +1 more source
Chemical Ligation of Backbone N‐hydroxylated Peptides
Chemistry – A European Journal, EarlyView.Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio +1 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Abstract The synthesis and characterization of an amphiphilic nitroxide to be used as a controlling agent in a nitroxide‐mediated living radical polymerization in aqueous dispersion media is presented. In the first stage of nitroxide synthesis (phthalimide protection), two reaction methods were employed: traditional and microwave.
Enrique García‐Leal +3 more
wiley +1 more source
Cancer Nexus, EarlyView.ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han +5 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
N,N-Bis(3β-acetoxypregn-5(6)-en-20-on-16α-yl)hydroxylamine
Molbank, 2015 A steroid with the dimeric structure, N,N-bis(3β-acetoxypregn-5(6)-en-20-on-16α-yl)hydroxylamine was synthesized in the base catalyzed reaction of 3β-acetoxypregn-5,16-dien-20-one with O-(trimethylsilyl)hydroxylamine.
Rita Skoda-Földes
doaj +1 more source
Characterization of the Reversible Inactivation of Ankistrodesmus braunii Nitrate Reductase by Hydroxylamine [PDF]
, 1986 Teresa Balandin +2 more
openalex +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
Nonresonant Surface‐Enhanced Hyper Raman Scattering of Aromatic Amino Acids on Gold Nanoparticles
Journal of Raman Spectroscopy, EarlyView.The surface‐enhanced hyper Raman spectra of the three aromatic amino acids phenylalanine, tryptophan, and tyrosine, obtained with nonresonant excitation at a wavelength of 1064 nm, are reported. The data are discussed in the context of the interaction of the molecules with two gold nanoparticle plasmonic substrates, as well as intermolecular ...
Fariha Binte Rahman, Janina Kneipp
wiley +1 more source
Efficient Separation of Hydroxylamine from Metal Ions by PIM-ED Process
SeparationsSelective separation of hydroxylamine (HA) from metal ions to prepare high-purity HA remains a challenge. In this study, given that HA can react with carbonyl compounds, TTA (thenoyltrifluoroacetone) was screened as a carrier to prepare the polymer ...
Lilei Yang +3 more
doaj +1 more source