Results 201 to 210 of about 10,973 (280)

Formal Dearomative Hydroamination of 2-Arylphenols. [PDF]

J Org Chem
Wiley RE, Eng MC, Clarkson AJ, Johnson JS.   +3 more
europepmc   +1 more source

Mechanisms controlling the plasma membrane targeting and the nanodomain organization of the plant SPFH protein HIR2

The Plant Journal, Volume 126, Issue 3, May 2026.
SUMMARY Plasma membranes (PM) contain myriads of diverse nanodomains that correspond to nanometric scale structures enriched in specific lipids and proteins acting as signaling/regulation hubs involved in diverse biological processes. So far, how PM nanodomains are formed and maintained in plant cells remains largely unknown.
Michal Daněk, Omar Hdedeh, Jesús Amo, Jessica Boutet, Michaela Neubergerová, Héla Safi, Anas Abuzeineh, Amanda Martín‐Barranco, Jean‐Bernard Fiche, Caroline Mercier, Baldwin Dumortier, Gabriel Krouk, Marcelo Nollmann, Roman Pleskot, Yohann Boutté, Véronique Santoni, Sébastien Mongrand, Alexandre Martinière, Enric Zelazny   +18 more
wiley   +1 more source

Development and Optimization of an Aminooxy Coupling Reaction to Prepare Multivalent Bioconjugates with a Single Noncanonical Amino Acid. [PDF]

Bioconjug Chem
Gourdie RK, Boyt EL, Flood BM, Williard AC, Eisen WI, Skeen TL, Hassler AR, Wang AS, Dimaranan CR, Rothman SK, King EA, Maza JC, Young DD.   +12 more
europepmc   +1 more source

Synthesis of 2‐Aryl(alkyl)benzimidazole Hydroxamic Acids as HDAC Inhibitors with Anti‐Angiogenesis Properties

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
2‐Aryl(alkyl)benzimidazole hydroxamic acids (11‐16) are potent and selective HDAC6 inhibitors, with minimal activity against HDAC1/2, and also display anti‐angiogenic and anticancer activities. Compound 13 exhibited a GI50 of 3.9 μM against EPCs and inhibited the growth of HCT‐116, SK‐Hep‐1, and PC‐3 cells with GI50 values of 1.3, 4.2, and 7.5 μM ...
Yi‐Ting Liu, Cheng‐Ta Lai, Shih‐Wei Wang, Shan‐Chi Liu, Yi‐Lin Hwang, Yi‐Chen Tsai, Chi‐Yeh Lee, Yu‐Wei Lai, Juei‐Yu Yen, Po‐Chuan Wang, Hsueh‐Yun Lee   +10 more
wiley   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources

Iron-Catalyzed Alkylation-Reduction of <i>N</i>-Methyl Nitrones via LMCT Activation. [PDF]

Org Lett
Gonçalves RO, Vélez JAC, Debia NP, Oliveira PHR, Larroza A, Alves D, Paixão MW.   +6 more
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Triazine‐Based Dual Histone Deacetylase/phosphatidylinositol 3‐kinase Inhibitors for Breast Cancer Therapy

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Breast cancer is the most frequently diagnosed malignancy and a leading cause of cancer‐related mortality among women worldwide. Triple‐negative breast cancer (TNBC) poses a major clinical challenge due to its aggressive nature, limited therapeutic options, and high propensity for drug resistance.
Lara Luzietti, Gustavo Salgado Pires, Ana Ryan, Crisamie Regidor, Matthew Hiller, Danilo Sarti, Tríona Ní Chonghaile, Pedro de Sena Murteira Pinheiro, Damir Varešlija, Daniel Alencar Rodrigues   +9 more
wiley   +1 more source

Catalytic Enantioselective Alkyne Addition to Nitrones Enabled by Tunable Axially Chiral Imidazole-Based P,N-Ligands. [PDF]

J Am Chem Soc
Yin S, Weeks KN, Aponick A.
europepmc   +1 more source

hydroxylamine salts [PDF]

Chemical & Engineering News Archive, 1953
openaire   +1 more source

Synthesis of chiral lactams by asymmetric nitrogen insertion. [PDF]

Chem Sci
Hammes J, Mañas C, Pedada A, Arnold M, Wahl JM.   +4 more
europepmc   +1 more source