Results 51 to 60 of about 111,305 (353)
Native Endophytes of Tripterygium wilfordii-Mediated Biotransformation Reduces Toxicity of Celastrol
Celastrol (1), obtained from the roots of Tripterygium wilfordii Hook F., is most likely to become an antitumor drug, but with severe cytotoxicity.
Ping-yang Ma+8 more
doaj +1 more source
Mammalian transient receptor potential ankyrin 1 (TRPA1) is a polymodal nociceptor that plays an important role in pain generation, but its role as a cold nociceptor is still controversial.
Takahito Miyake+10 more
semanticscholar +1 more source
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
wiley +1 more source
On the heterogeneity of the mitochondrial C27-steroid 26-hydroxylase system
Mitochondrial 26-hydroxylation of exogenous cholesterol, endogenous cholesterol, and 5β-cholestane-3α,7α,12α-triol was studied. 26-Hydroxylation of endogenous cholesterol was measured by mass fragmentography.
J Gustafsson
doaj
The regulatory mechanisms of proline and hydroxyproline metabolism: Recent advances in perspective
For diverse human tumors, growth and metastasis are dependent on proline synthesis, but the mechanisms underlying this association are not clear. Proline incorporated into collagen is primarily synthesized from glutamine.
James M. Phang
doaj +1 more source
Yellow and red-violet betalain plant pigments are restricted to several families in the order Caryophyllales, where betacyanins play analogous biological roles to anthocyanins. The initial step in betalain biosynthesis is the hydroxylation of tyrosine to
Rasika Sunnadeniya+7 more
semanticscholar +1 more source
A multi‐generational compositional design creates a printable low‐loss dielectric composite that achieves over 16 W m−1 K−1. This breakthrough is enabled by thermal post‐processing, which promotes templated crystallization in a polymer matrix from surface‐modified particles, creating a “hetero‐percolated network.” The resulting material is three ...
Daniel J. Braconnier+6 more
wiley +1 more source
Characterization of 6 alpha-hydroxylation of taurochenodeoxycholic acid in pig liver.
The properties of the species-specific 6 alpha-hydroxylation of taurochenodeoxycholic acid were studied in subcellular fractions from pig liver. The hydroxylation was observed in microsomes but not in mitochondria.
H Boström
doaj
Biotransformation of Isoflavone Using Enzymatic Reactions
The roles of cytochrome P450 monooxygenases (CYPs) from Streptomyces spp. which are called the “treasure islands” for natural products for medicine and antibiotics are not well understood.
Changhyun Roh
doaj +1 more source
A dicopper(II) complex, stabilized by the bis(tpa) ligand 1,2-bis[2-[bis(2-pyridylmethyl)aminomethyl]-6-pyridyl]ethane (6-hpa), [Cu2 (μ-OH)(6-hpa)]3+ , was synthesized and structurally characterized.
Tomokazu Tsuji+8 more
semanticscholar +1 more source