Results 61 to 70 of about 97,747 (236)

Effect of biliary obstruction on 26-hydroxylation of C27-steroids in bile acid synthesis

open access: yesJournal of Lipid Research, 1978
The effect of biliary obstruction on side chain hydroxylations in the biosynthesis and metabolism of bile acids was studied in the rat. For comparison, several other hydroxylation reactions in bile acid biosynthesis and metabolism were assayed.
J Gustafsson
doaj  

Native Endophytes of Tripterygium wilfordii-Mediated Biotransformation Reduces Toxicity of Celastrol

open access: yesFrontiers in Microbiology, 2022
Celastrol (1), obtained from the roots of Tripterygium wilfordii Hook F., is most likely to become an antitumor drug, but with severe cytotoxicity.
Ping-yang Ma   +8 more
doaj   +1 more source

The regulatory mechanisms of proline and hydroxyproline metabolism: Recent advances in perspective

open access: yesFrontiers in Oncology, 2023
For diverse human tumors, growth and metastasis are dependent on proline synthesis, but the mechanisms underlying this association are not clear. Proline incorporated into collagen is primarily synthesized from glutamine.
James M. Phang
doaj   +1 more source

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

open access: yesNature Communications, 2016
Mammalian transient receptor potential ankyrin 1 (TRPA1) is a polymodal nociceptor that plays an important role in pain generation, but its role as a cold nociceptor is still controversial.
Takahito Miyake   +10 more
semanticscholar   +1 more source

2D titanium carbonitrides and their hydroxylated derivatives: Structural, electronic properties and stability of MXenes Ti3C2-xNx and Ti3C2-xNx(OH)2 [PDF]

open access: yes, 2013
3D titanium carbonitrides TiCxNy possess excellent physical, chemical, and mechanical properties, attractive for various industrial applications. Most recently, the uncommon nano-sized layers of 2D-like titanium carbonitrides were fabricated from MAX phases.
arxiv   +1 more source

On the heterogeneity of the mitochondrial C27-steroid 26-hydroxylase system

open access: yesJournal of Lipid Research, 1976
Mitochondrial 26-hydroxylation of exogenous cholesterol, endogenous cholesterol, and 5β-cholestane-3α,7α,12α-triol was studied. 26-Hydroxylation of endogenous cholesterol was measured by mass fragmentography.
J Gustafsson
doaj  

Biotransformation of Isoflavone Using Enzymatic Reactions

open access: yesMolecules, 2013
The roles of cytochrome P450 monooxygenases (CYPs) from Streptomyces spp. which are called the “treasure islands” for natural products for medicine and antibiotics are not well understood.
Changhyun Roh
doaj   +1 more source

Tyrosine Hydroxylation in Betalain Pigment Biosynthesis Is Performed by Cytochrome P450 Enzymes in Beets (Beta vulgaris)

open access: yesPLoS ONE, 2016
Yellow and red-violet betalain plant pigments are restricted to several families in the order Caryophyllales, where betacyanins play analogous biological roles to anthocyanins. The initial step in betalain biosynthesis is the hydroxylation of tyrosine to
Rasika Sunnadeniya   +7 more
semanticscholar   +1 more source

Characterization of 6 alpha-hydroxylation of taurochenodeoxycholic acid in pig liver.

open access: yesJournal of Lipid Research, 1988
The properties of the species-specific 6 alpha-hydroxylation of taurochenodeoxycholic acid were studied in subcellular fractions from pig liver. The hydroxylation was observed in microsomes but not in mitochondria.
H Boström
doaj  

Specific Enhancement of Catalytic Activity by a Dicopper Core: Selective Hydroxylation of Benzene to Phenol with Hydrogen Peroxide.

open access: yesAngewandte Chemie, 2017
A dicopper(II) complex, stabilized by the bis(tpa) ligand 1,2-bis[2-[bis(2-pyridylmethyl)aminomethyl]-6-pyridyl]ethane (6-hpa), [Cu2 (μ-OH)(6-hpa)]3+ , was synthesized and structurally characterized.
Tomokazu Tsuji   +8 more
semanticscholar   +1 more source

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