Results 81 to 90 of about 85,771 (308)

C5-Hydroxylation of Liquirtigenin Is Catalyzed Selectively by CYP1A2

, 2010
C5-Hydroxylation of Liquirtigenin Is Catalyzed Selectively by ...
胡莹, 杨凌, 刘慧鑫
core  

Machine Learning Interatomic Potentials for Energy Materials: Architectures, Training Strategies, and Applications

Advanced Energy Materials, EarlyView.
Machine learning interatomic potentials bridge quantum accuracy and computational efficiency for materials discovery. Architectures from Gaussian process regression to equivariant graph neural networks, training strategies including active learning and foundation models, and applications in solid‐state electrolytes, batteries, electrocatalysts ...
In Kee Park, Saeed Pourasad, Jinhong Mun, Arunkumar Chitteth Rajan, Tae Hyeon Park, Anand Rohit, Mohammad Zafari, Tan‐Lien Pham, Eunjae Jung, Bonseung Koo, Miran Ha, Gi Beom Sim, Hyun Gyu Park, Won Woong Choi, Kwanghyeon Jo, Soohaeng Yoo Willow, David ChangMo Yang, Chang Woo Myung, Geunsik Lee, Kwang S. Kim   +19 more
wiley   +1 more source

A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery

, 2008
Background: Several human pathologies, including neoplasia and ischemic cardiovascular diseases, course with an unbalance between oxygen supply and demand ( hypoxia).
Alcaide-German, ML, Del Peso, L, Garcia-Fernandez, LF, Vara-Vega, A, Landazuri, MO   +4 more
core  

Developmental and Phenotypic Outcomes in Mild Phenylalanine Hydroxylase Deficiency

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Benign hyperphenylalaninemia (bHPA) is defined as elevated phenylalanine (Phe) levels remaining ≤ 360 μmol/L (6 mg/dL) and not requiring medical intervention. Individuals with bHPA may demonstrate a rise in their Phe levels > 360 μmol/L, effectively developing a mild PKU phenotype requiring therapy to prevent neurocognitive complications. This
Aaron Williams, Kristian Divin, Lindsay C. Burrage, William J. Craigen, Fernando Scaglia, Claudia Soler‐Alfonso, V. Reid Sutton, Kevin E. Glinton, Ronit Marom   +8 more
wiley   +1 more source

Enhanced benzene hydroxylation inside carbon nanotubes and the confinement effects

, 2012
Enhanced benzene hydroxylation inside carbon nanotubes and the confinement ...
包信和, 张洪波, 潘秀莲, 张帆
core  

65 Chapter 3 Active Site Engineering of P450 BM3 for

, 2014
To compare the functional richness of mutagenesis libraries generated by error-prone PCR, site-saturation mutagenesis, combinatorial active site saturation with a reduced set of amino acids and structure-based computational library design, seventeen ...
Small Alkane Hydroxylation
core  

Green Polyols from Tamanu Seed Oil: Reaction Kinetics and Process Optimization

Communications in Science and Technology
Using methanol, this study examined the hydroxylation process of epoxidized tamanu seed oil (ETSO), with an oxirane number of 3.92 to 4.04 mmol/g, under the catalyzation of sulfuric acid (H2SO4).
Eni Budiyati, Mohammad Sofyan Habibburohman, Nur Ahmad Fauzi, Muhammad Azim Wasi, Malik Musthofa, Anisa Ur rahmah   +5 more
doaj   +1 more source

A Novel 3-Phytosterone-9α-Hydroxylase Oxygenation Component and Its Application in Bioconversion of 4-Androstene-3,17-Dione to 9α-Hydroxy-4-Androstene-3,17-Dione Coupling with A NADH Regeneration Formate Dehydrogenase

Molecules, 2019
9α-Hydroxy-4-androstene-3,17-dione (9-OH-AD) is one of the significant intermediates for the preparation of β-methasone, dexamethasone, and other steroids. In general, the key enzyme that enables the biotransformation of 4-androstene-3,17-dione
Xian Zhang, Manchi Zhu, Rumeng Han, Youxi Zhao, Kewei Chen, Kai Qian, Minglong Shao, Taowei Yang, Meijuan Xu, Jianzhong Xu, Zhiming Rao   +10 more
doaj   +1 more source

Iodine promoted alpha-hydroxylation of ketones

, 2015
A novel method for alpha-hydroxylation of ketones using substoichiometric amount of iodine under metalfree conditions is described. This method has been successfully employed in synthesizing a variety of heterocyclic compounds, which are useful ...
Siddaraju, Yogesh, Prabhu, Kandikere Ramaiah   +1 more
core   +1 more source

Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold.

, 2009
Ankyrin repeats (ARs) are one of the most common structural motifs among eukaryotic proteins. Recent analyses have shown that factor inhibiting hypoxia-inducible factor (FIH) catalyses the hydroxylation of highly conserved Asn-residues within ankyrin ...
Coleman, ML, Ratcliffe, Peter, Kelly, L, McDonough, MA, Schofield, Christopher   +4 more
core   +2 more sources