Results 81 to 90 of about 95,661 (297)

Intermolecular water attack to alkenylgold carbenes derived from 3-propargylindoles

Beilstein Journal of Organic Chemistry
An intermolecular hydroxylation of α,β-unsaturated gold carbene intermediates, generated from readily accessible 3-propargylindoles through a tandem 1,2-indole migration–hydroxylation sequence using water as an external nucleophile, has been developed ...
Lorena Renedo, Marta Solas, Samuel Suárez-Pantiga, Roberto Sanz   +3 more
doaj   +1 more source

A Novel 3-Phytosterone-9α-Hydroxylase Oxygenation Component and Its Application in Bioconversion of 4-Androstene-3,17-Dione to 9α-Hydroxy-4-Androstene-3,17-Dione Coupling with A NADH Regeneration Formate Dehydrogenase

Molecules, 2019
9α-Hydroxy-4-androstene-3,17-dione (9-OH-AD) is one of the significant intermediates for the preparation of β-methasone, dexamethasone, and other steroids. In general, the key enzyme that enables the biotransformation of 4-androstene-3,17-dione
Xian Zhang, Manchi Zhu, Rumeng Han, Youxi Zhao, Kewei Chen, Kai Qian, Minglong Shao, Taowei Yang, Meijuan Xu, Jianzhong Xu, Zhiming Rao   +10 more
doaj   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

Operando Identification of the Active Phase in Sr‐Promoted Lanthanum Cobaltite Perovskite‐Derived Catalysts for Ammonia Decomposition

Angewandte Chemie, EarlyView.
Ammonia decomposition catalyzed by base metals: Exsolution of cobalt from perovskites prepared by spray‐flame synthesis (SFS) yields highly active, SrO‐promoted Co/La2O3 catalysts with low cobalt content. Operando studies provide insight into the function of the promoter. Dynamic surface reconstruction under operating conditions increases the interface
Barış Alkan, Liseth Duarte‐Correa, Detre Teschner, Kassiogé Dembélé, Mino Borrelli, Anh Binh Ngo, Konstantinos Kappis, Mattia Scardamaglia, Zohreh Asadi, Wiebke Riedel, Thomas Risse, Frank Girgsdies, Gregor Koch, Olaf Timpe, Axel Knop‐Gericke, Thomas Lunkenbein, Annette Trunschke   +16 more
wiley   +2 more sources

Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?

International Journal of Nanomedicine, 2019
Yongbing Sun,1 Jianping Gong,1 Yi Cao2 1National Engineering Research Center for Solid Preparation Technology of Chinese Medicines, Jiangxi University of Traditional Chinese Medicines, Jiangxi, Nanchang 330006, People’s Republic of China; 2Key ...
Sun Y, Gong J, Cao Y
doaj  

On the heterogeneity of the mitochondrial C27-steroid 26-hydroxylase system

Journal of Lipid Research, 1976
Mitochondrial 26-hydroxylation of exogenous cholesterol, endogenous cholesterol, and 5β-cholestane-3α,7α,12α-triol was studied. 26-Hydroxylation of endogenous cholesterol was measured by mass fragmentography.
J Gustafsson
doaj   +1 more source

Direct hydroxylation of benzene to phenol over a new vanadium-substituted phosphomolybdate as a solid catalyst

, 2008
With aqueous hydroxylation as oxidant, Benzene was directly hydroxylated to phenol with phenol yield of 12.4% and selectivity of 85.7% over tetramethyl ammonium 11- molybdo -1- vanadophosphates [(CH3)4N]4PMo11VO40 as a solid catalyst, which was testifed ...
陈佳琦, 高爽, 徐杰
core  

An Iminium Salt Organocatalyst for Selective Aliphatic C–H Hydroxylation

, 2016
The first examples of catalysis of aliphatic C–H hydroxylation by an iminium salt are presented. The method allows the selective organocatalytic hydroxylation of unactivated 3° C–H bonds at room temperature using hydrogen peroxide as the terminal oxidant.
William G. Shuler (1666594), Conor J. Pierce (2112832), Daoyong Wang (478826), Michael K. Hilinski (1702192)   +3 more
core   +1 more source

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source

Van der Waals Gap‐Confined Molecular Engineering of MoS2 for Selectivity‐Enhanced and Humidity‐Tolerant Gas Sensing

Advanced Science, EarlyView.
Molecular confinement within van der Waals gaps of MoS2 is established as a powerful design strategy for selective and stable chemical sensing. Ethanol‐confined films simultaneously tune electronic doping, surface wettability, and sulfur vacancy configurations, suppressing water interference while enhancing NO2 adsorption.
Jae Hyung Shim, Gwang Su Kim, Tae Hyung Lee, Jaeho Lee, Su‐Yeon Joung, Jung Hoon Kang, Jin Seok Kim, Jung‐Won An, Chong‐Yun Kang, Ho Won Jang, Jungwon Park, Ji‐Soo Jang, Chul‐Ho Lee   +12 more
wiley   +1 more source