Results 101 to 110 of about 85,771 (308)

The hydroxylation of ?5-androstenes by Cephalosporium aphidicola

open access: yes, 1998
Whereas the major hydroxylation product of 3?-hydroxy-5?-androstan-17-one by Cephalosporium aphidicola is the 11?-alcohol, the presence of a ?5-double bond in the substrate leads to non-stereospecific allylic hydroxylation at C–7.
Christy Hunter (17160439)   +2 more
core   +1 more source

The Remarkable Structural Diversity Achieved in ent-Kaurane Diterpenes by Fungal Biotransformations

open access: yesMolecules, 2014
The use of biotransformations in organic chemistry is widespread, with highlights of interesting applications in the functionalization of natural products containing unactivated carbons, like the kaurane diterpenes.
Jacqueline A. Takahashi   +4 more
doaj   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Stereochemistry of the α-oxidation of 3-methyl-branched fatty acids in rat liver

open access: yesJournal of Lipid Research, 1999
The stereochemistry of the α-oxidation of 3-methyl-branched fatty acids was studied in rat liver. R- and S-3-methylhexadecanoic acid were equally well α-oxidized in intact hepatocytes and homogenates.
Kathleen Croes   +4 more
doaj   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

open access: yesArthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven   +6 more
wiley   +1 more source

Dynamics of Antimicrobial Peptide Encapsulation in Carbon Nanotubes: The Role of Hydroxylation

open access: yesInternational Journal of Nanomedicine, 2022
Maryam Zarghami Dehaghani,1 Farrokh Yousefi,2 Farzad Seidi,1 S Mohammad Sajadi,3,4 Navid Rabiee,5 Sajjad Habibzadeh,6 Amin Esmaeili,7 Amin Hamed Mashhadzadeh,8 Christos Spitas,8 Ebrahim Mostafavi,9,10 Mohammad Reza Saeb11 1Jiangsu Co-Innovation Center of
Zarghami Dehaghani M   +10 more
doaj  

Hydroxylation of anilides by engineered cytochrome P450BM3

open access: yes, 2017
Biocatalytic direct monohydroxylation of anilides has been achieved on preparative scale using mutant cytochrome P450BM3 enzymes. Representative mono- and disubstituted N-trifluoromethanesulfonyl anilides are shown to be converted in most cases to the ...
Luet Lok Wong   +12 more
core   +1 more source

Tissue Damage in Rheumatoid Arthritis Is Genetically Linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts

open access: yesArthritis &Rheumatology, EarlyView.
Objective Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biologic mechanism underlying this association. Methods Expression of surrounding genes was compared among rs26232 genotypes.
Kevin J. Sheridan   +12 more
wiley   +1 more source

Recent Strategies Toward Durable and Ion‐Tolerant Transition Metal‐Based Electrocatalysts in Seawater Electrolysis

open access: yesCarbon Energy, EarlyView.
Recent strategies address these challenges through ion‐specific regulation, encompassing chloride‐tolerant and chloride‐regulating anodes together with cathode designs that suppress OH− accumulation and Mg2+/Ca2+ coupling. This ion‐management‐oriented framework provides general guidelines for achieving stable, selective, and scalable seawater ...
Lina Li   +5 more
wiley   +1 more source

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

open access: yes, 2012
The finding that oxygenase-catalyzed protein hydroxylation regulates animal transcription raises questions as to whether the translation machinery and prokaryotic proteins are analogously modified.
Hamed, Refaat B   +63 more
core   +2 more sources

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