Results 111 to 120 of about 95,661 (297)

Adenylosuccinate lyase hydroxylation contributes to triple negative breast cancer via the activation of cMYC

, 2020
Hydroxylation is a post-translational modification affecting protein stability, activity or interactome. We identified adenylosuccinate lyase (ADSL) as a novel hydroxylation substrate in triple negative breast cancer. Hydroxylation affects ADSL enzymatic
Giada Zurlo, Qing Zhang
core   +1 more source

Simultaneous H2O:O2 Co‐Reactant Pulsing for Functional Property Control of Atomic Layer Deposited ZnO, TiO2, and Al2O3 Thin Films

Advanced Materials Interfaces
Fabrication of metal‑oxide thin films with precisely controlled crystallographic texture and defect chemistry is an increasingly important target in atomic layer deposition (ALD), in efforts to optimize the application performance of these thin films ...
Ramin Ghiyasi, Maarit Karppinen
doaj   +1 more source

Methanol Decomposition on TiO2 Under Ambient Conditions: Cooperative Proton Transfer at Hydrated Interfaces

Angewandte Chemie International Edition, EarlyView.
Under ambient conditions, the TiO2 surface becomes hydrated by adsorbed hydroxyl groups (OH) and water molecules. This surface hydration promotes methanol decomposition, rendering the first deprotonation step nearly barrierless compared with ideal UHV conditions.
Milad Salarinasab, Julian Andreas Hochhaus, Jing Wang, Aimeric Ouvrard, Anas Akhtar, Michele Capra, Kristina Tschulik, Carsten Westphal, Mirko Cinchetti, Bo Wen, Li‐Min Liu, Zhe Wang, Ahmed Ghalgaoui   +12 more
wiley   +1 more source

Peroxidase Can Perform the Hydroxylation Step in the "oxidative Cascade" during Oxidation of Tea Catechins

, 2016
The formation of black tea thearubigins involves at least two of the following oxidation steps: (i) oligomerization, (ii) rearrangement, and (iii) hydroxylation.
Vincken, Jean Paul, Gruppen, Harry, Jean-Paul Vincken (550043), Harry Gruppen (550039), Verloop, Annewieke J.W., Annewieke J. W. Verloop (2097367)   +5 more
core   +1 more source

Extending Peptide Ligation to Acidic pH and Junctions Comprising Glycosylated and Phosphorylated Amino Acids

Angewandte Chemie International Edition, EarlyView.
A pyridine‐containing ligation auxiliary eliminates a major bottleneck of peptide ligation chemistry. The extended range of applicable pH values (2.0–7.5) in the ligation reaction helps to avoid epimerization. Native chemical ligation (NCL) proceeds at virtually any junction, including reactions at β‐branched amino acids, as well as O‐glycosylated or O‐
Sebastian Trunschke, Antonia Feida, Hendrik Hanebrink, Arseniy Galashov, Alina Herfort, Oliver Seitz   +5 more
wiley   +1 more source

DFT-assisted rational design of salan ligands for highly enantioselective Zr-salan-catalyzed hydroxylation of cyclic <i>β</i>-keto esters. [PDF]

Smart Mol
Guided by DFT calculations, the design of novel C1‐symmetric salan ligands without the involvement of Suzuki coupling was achieved, and the preparation of α‐hydroxy‐β‐ketoesters in 99% yield and 99% ee was realized under low catalyst loading. Abstract In this work, a structurally simple, inexpensive, and readily accessible Zr–salan catalytic system was
Ma C, Tang K, Jiang Y, Zhu H, Wu Y, Xing Y, Wang Y, Liu Q, Du J, Meng Q.   +9 more
europepmc   +2 more sources

Ultrafast Dynamics of a Red-Light-Activated Organic Photocatalyst in the Oxidative Hydroxylation of Phenylboronic Acid [PDF]

Over the past few years, photoredox catalysis has led to significant transformations in modern synthetic chemistry. It has allowed the development of new synthetic pathways for the assembly of complex molecular scaffolds using light as a driving force ...
Vanessa, Huxter, Anshu, Kumar, Thomas, Gianetti, Md Mubarak , Hossain, Benjamin, Thompson   +4 more
core   +2 more sources

Beyond Protein Synthesis: The Multifunctional Role of Functional Amino Acids in Modulating Meat Quality in Ruminants

Animal Research and One Health, EarlyView.
Multifunctional roles of functional amino acids in regulating meat quality in ruminants: Functional amino acids (FAAs) regulate ruminant meat quality through multiple interconnected mechanisms, including antioxidant protection, metabolic regulation, signal transduction, structural support, and gene expression modulation.
Zixin Liu, Tian Xia, Xiaokang Lv, Man Ren, Chuanshe Zhou, Zhiliang Tan   +5 more
wiley   +1 more source

Effect of aging on cholesterol 7 alpha-hydroxylation in humans

, 1993
In order to investigate the alterations of bile acid synthesis in aging, we studied the rates of cholesterol 7 alpha-hydroxylation, the rate-limiting step, in 28 patients of different ages (34-83 years old, 14 below and 14 above the age of 65) of both ...
LORIA, Paola, A. PINETTI, CARUBBI, Francesca, N. ABATE, CARULLI, Nicola, M. CONCARI, S. BERTOLOTTI, R. MESSORA, BERTOLOTTI, Marco, P Loria, M Concari, R Messora, F Carubbi, S Bertolotti, N Carulli, M Bertolotti, A Pinetti, N Abate   +17 more
core   +1 more source

Valorization of Textile Waste: Enzymatic Upcycling of Terephthalic Acid Toward a Sustainable PET Value Chain

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT The rapid expansion of the global textile industry, driven by the fast‐fashion paradigm, which is characterized by low‐cost, short‐lived garments made from inexpensive synthetic fibers, has intensified environmental pressures through increased waste generation, resource depletion, microplastic pollution, and greenhouse gas emissions ...
Fares Al‐Ostoot, Loredano Pollegioni, Elena Rosini   +2 more
wiley   +1 more source