Results 1 to 10 of about 11,676 (155)

Mixed function oxygenases and xenobiotic detoxication/toxication systems in bivalve molluscs [PDF]

Helgoländer Wissenschaftliche Meeresuntersuchungen, 1980
Components of a xenobiotic detoxication/toxication system involving mixed function oxygenases are present inMytilus edulis. Our paper critically reviews the recent literature on this topic which reported the apparent absence of such a system in bivalve molluscs and attempts to reconcile this viewpoint with our own findings on NADPH neotetrazolium ...
Michael N Moore
exaly   +2 more sources

Physiological modeling of isoprene dynamics in exhaled breath [PDF]

, 2010
Human breath contains a myriad of endogenous volatile organic compounds (VOCs) which are reflective of ongoing metabolic or physiological processes.
Alexander Kupferthaler, Amann, Amann, Amann, Anderson, Anderson, Anton Amann, Banks, Banks, Batzel, Bock, Bogaards, Box, Brown, Brun, Buszewski, Cailleux, Cailleux, Cailleux, Capodicasa, Capodicasa, Cintrón-Arias, Cobelli, Cope, Csanády, Davidian, Deneris, Dogan, Farhi, Filser, Fritz, Gelmont, Gerald Teschl, Gerlowski, Golub, Hairer, Hartmann, Hartmann Hinterhuber, Helin Koc, Hengl, Huet, Hughes, Jacquez, Johnson, Julian King, Karl, Karl Unterkofler, Kharitonov, King, Kinoyama, Kuhn, Kumagai, Kushch, Leung, Liang, Ligor, Lindinger, Lindinger, Lirk, Ljung, Lumb, McGrath, Melnick, Melnick, Miekisch, Miekisch, Miekisch, Mohrman, Monte, Mörk, Mörk, Nelson, Ottesen, Pabst, PaweŁ Mochalski, Peifer, Pleil, Pleil, Rieder, Rodriguez-Fernandez, Salerno-Kennedy, Schwarz, Seber, Shao, Silver, Smith, Smith, Stone, Sullivan, Susanne Teschl, Taucher, Tothill, Turner, Wagner, Wagner, Watson, Weitzberg, West   +97 more
core   +6 more sources

CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms

Molecular Cancer, 2006
Background Gene-targeted iMycEμ mice that carry a His6-tagged mouse Myc(c-myc)cDNA, MycHis, just 5' of the immunoglobulin heavy-chain enhancer, Eμ, are prone to B cell and plasma cell neoplasms, such as lymphoblastic B-cell lymphoma (LBL) and ...
Maeng Sung-Ho, DuBois Wendy, Chung Seung-Tae, Peng Liangping, Han Seong-Su, Shaffer Arthur L, Sporn Michael B, Janz Siegfried   +7 more
doaj   +1 more source

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota [PDF]

, 2014
Dietary intake of L-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide (TMAO) by hepatic flavin-containing monooxygenases.
Bugg, Tim, Chen, Yin, Cosatti, Marialuisa, Jameson, Eleanor, Rajakumar, Kumar, Schäfer, Hendrik, Zhu, Yijun   +6 more
core   +1 more source

Enzymatic functionalization of carbon-hydrogen bonds [PDF]

, 2011
The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H., Coelho, Pedro S., Lewis, Jared C.   +2 more
core   +1 more source

Degradation of BTEX by anaerobic bacteria: physiology and application [PDF]

, 2010
Pollution of the environment with aromatic hydrocarbons, such as benzene, toluene, ethylbenzene and xylene (so-called BTEX) is often observed. The cleanup of these toxic compounds has gained much attention in the last decades.
Eekert, M.H.A., van, Stams, A.J.M., Weelink, S.A.B.   +2 more
core   +2 more sources

Expression of mRNA for phospholipase A(2), cyclooxygenases, and lipoxygenases in cultured human umbilical vascular endothelial and smooth muscle cells and in biopsies from umbilical arteries and veins [PDF]

, 1998
Arachidonic acid (AA) is released by phospholipase A(2) (PLA(2)) and then converted into vasoactive and inflammatory eicosanoids by cyclooxygenases (COX) and lipoxygenases (LOX).
Carlsson, Maria, Gidlöf, Anders, Sirsjö, Allan, Söderkvist, Peter, Uhl, Eberhard, Öst, Martin   +5 more
core   +1 more source

Strigolactone biosynthesis is evolutionarily conserved, regulated by phosphate starvation and contributes to resistance against phytopathogenic fungi in a moss, Physcomitrella patens [PDF]

, 2017
In seed plants, strigolactones (SLs) regulate architecture and induce mycorrhizal symbiosis in response to environmental cues. SLs are formed by combined activity of the carotenoid cleavage dioxygenases (CCDs) 7 and 8 from 9-cis-β-carotene, leading to ...
Alder, Adrian, Balakrishna, Aparna, Decker, Eva L., Ferguson, Jenny, Hunn, Stefan, Kerres, Klaus L., Lehtonen, Mikko T., Nordzieke, Steffen, Safavi-Rizi, Vajiheh, Scheler, Bjoern, Wiedemann, Gertrud, Ávalos Cordero, Francisco Javier   +11 more
core   +1 more source

Modifications of drug metabolism by disulfiram and diethyldithiocarbamate I. Mixed-function oxygenase

Chemico-Biological Interactions, 1976
Disulfiram and diethyldithiocarbamate were administered to rats for 4 days alone (300 mg/kg, daily, per os) or in combination with phenobarbital (80 mg/kg, daily, i.p.), in order to observe the effects of these compounds on the microsomal membrane components and on the mixed-function oxygenase system.
Lang, Matti, Marselos, Marios, Torronen, Riitta   +2 more
openaire   +5 more sources

Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size [PDF]

, 2016
Calcium-independent phospholipase A(2)γ (iPLA(2)γ) is a mitochondrial enzyme that produces lipid second messengers that facilitate opening of the mitochondrial permeability transition pore (mPTP) and contribute to the production of oxidized fatty acids ...
Abendschein, Dana, Gibson Dilthey, Beverly, Gross, Richard W, Guan, Shaoping, Jenkins, Christopher M, Kovacs, Attila, Liu, Xinping, Mancuso, David J, Moon, Sung Ho, Nguyen, Annie L, Sims, Harold F, Weinheimer, Carla J, Yang, Kui   +12 more
core   +2 more sources