Results 41 to 50 of about 11,772 (251)

Expanding the set of rhodococcal Baeyer–Villiger monooxygenases by high-throughput cloning, expression and substrate screening [PDF]

, 2012
To expand the available set of Baeyer–Villiger monooxygenases (BVMOs), we have created expression constructs for producing 22 Type I BVMOs that are present in the genome of Rhodococcus jostii RHA1.
A Alfieri, A. Riebel, C Szolkowy, D Sheng, DE Torres Pazmiño, DE Torres Pazmiño, DE Torres Pazmiño, E Bloois van, F Hollmann, F Secundo, F Zambianchi, G Gonzalo de, G. de Gonzalo, H. M. Dudek, HM Dudek, I Letunic, JD Stewart, JD Thompson, K Tamura, L. Rychlewski, M Ahmad, M Bocola, M Miyamoto, M Renz, M Seto, M. W. Fraaije, MD Mihovilovic, MD Mihovilovic, MP McLeod, MW Fraaije, MW Fraaije, MW Fraaije, NM Kamerbeek, NM Kamerbeek, NM Kamerbeek, P. Stepniak, R Orru, S Saheki, S Wu   +38 more
core   +4 more sources

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Fat mass and obesity-associated obesity-risk genotype is associated with lower foetal growth: An effect that is reversed in the offspring of smoking mothers [PDF]

, 2012
Fat mass and obesity-associated (FTO) gene variants are associated with childhood and adult obesity; however, the influence of FTO polymorphisms on foetal growth is unknown.
Beilin, L. J., Briollais, L., Hofman, A., Jaddoe, V. W. V., Lye, S. J., Marsh, J. A., Mook-Kanamori, D., Newnham, J.P., Palmer, L. J., Pennell, C. E., Steegers, E., Warrington, N. M.   +11 more
core   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Myo‐Inositol Mitigates Oxidative Stress in Bovine Mammary Epithelial Cells via Activation of the SIRT5/Nrf2 Signaling Axis

Animal Research and One Health, EarlyView.
Myo‐inositol alleviates oxidative stress in dairy cow mammary epithelial cells via the Sirt5/Nrf2 pathway to promote mitochondrial fusion. This graphical abstract was created with BioRender.com. ABSTRACT High‐yielding dairy cows are susceptible to mammary gland oxidative stress due to prolonged intensive lactation, leading to redox imbalance.
Yufei Zhang, Yu Cao, Meng Zhang, Huijie Hu, He Ma, Junlong Bi, Juxiong Liu, Shoupeng Fu, Wenjin Guo   +8 more
wiley   +1 more source

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE. [PDF]

, 2017
The Jeotgalicoccus sp. peroxygenase cytochrome P450 OleTJE (CYP152L1) is a hydrogen peroxide-driven oxidase that catalyzes oxidative decarboxylation of fatty acids, producing terminal alkenes with applications as fine chemicals and biofuels ...
Amaya, Belcher, Daff, Denisov, Dennig, Driscoll, Fujishiro, Girhard, Girvan, Grant, Grant, Groves, Herman, Hrycay, Imai, Joo, Joyce, Kapust, Lee, Li, Liu, Matsunaga, Matsunaga, Matsunaga, Matsunaga, Matsunaga, McIver, McLean, Morrison, Munro, Ost, Ost, Perera, Raag, Rittle, Rude, Yan, Zachos, Zhang   +38 more
core   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Marine crude-oil biodegradation: a central role for interspecies interactions [PDF]

, 2012
The marine environment is highly susceptible to pollution by petroleum, and so it is important to understand how microorganisms degrade hydrocarbons, and thereby mitigate ecosystem damage. Our understanding about the ecology, physiology, biochemistry and
Folwell, Benjamin D, McGenity, Terry J, McKew, Boyd A, Sanni, Gbemisola O   +3 more
core   +1 more source

Beyond CO2: Incorporating Bicarbonate, Dynamic Carbon Speciation, and Stoichiometric Plasticity Into Algal Growth Models

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The design of biological carbon capture systems to uptake carbon dioxide by photoautotrophic cultivation of algae has been proposed to mitigate atmospheric carbon emissions. Multiple models to predict algal growth as a function of nutrients have been proposed, but few have delved into the complex dynamic reactions of algal growth as influenced
Elizabeth Flanagan, Caye Drapcho, Mary Katherine Watson   +2 more
wiley   +1 more source

Thermodynamic Evaluation of Dual Substrate Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Various C₁–C₂ compounds are increasingly available through electrochemical reduction of CO2. Although not always suitable as a sole substrate, these compounds can supplement a primary substrate like glucose to enhance microbial growth. Yet, the mechanisms underlying the effects of dual substrate consumption on growth rate and growth yield ...
Marit A. Verheijen, Tim Meyboom, Mark C. M. van Loosdrecht, Rebeca Gonzalez‐Cabaleiro   +3 more
wiley   +1 more source