Results 61 to 70 of about 6,637 (223)

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

The FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi, Ayumu Takahashi, So Murakami, Nami Adachi, Tina Fujimoto, Yohta Fukuda, Taku Yamashita, Tsuyoshi Inoue, Hirofumi Tsujino   +8 more
wiley   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

International Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota, Klaus Kümmerer, Isabel Martins de Almeida, Emília Sousa   +3 more
wiley   +1 more source

HIV-protease inhibitors impair vitamin D bioactivation to 1,25-dihydroxyvitamin D

, 2003
BACKGROUND: A high prevalence of bone demineralization occurs in people living with HIV/AIDS. The contribution of HIV itself and its treatment is still unclear. Protease inhibitors (PIs) are potent inhibitors of the cytochrome p450 enzyme system.
M. Cozzolino, K. E. Yarasheski, P. Tebas, M. Vidal, A. S. Dusso, M. V. Arcidiacono   +5 more
core   +1 more source

Impact of the invasive diatom species Cymbella janischii on riverine microbial biofilm communities and a potential role of bacterially produced zeatin

Journal of Phycology, EarlyView.
Abstract The diatom Cymbella janischii is an invasive species in Japan, causing nuisance blooms by forming thick mats in rivers. To date, there are no documented studies on the microbiome associations in C. janischii mats or the processes that drive bloom formation.
Eldrin D. L. R. Arguelles, Kana Mugikura, Shinya Sato   +2 more
wiley   +1 more source

Integrative taxonomy of Harveylithon (Corallinales, Rhodophyta) reveals three new species from Korea and expanded diversity in the northwestern Pacific

Journal of Phycology, EarlyView.
Abstract Non‐geniculate coralline genus Harveylithon includes 12 species worldwide. In this study, we propose three new species, Ha. koreanum sp. nov., Ha. longiforme sp. nov., and Ha. planiforme sp. nov., based on integrative molecular and morphological analyses.
Gwan Woung Kim, So Young Jeong, Boo Yeon Won, Suzanne Fredericq, Tae Oh Cho   +4 more
wiley   +1 more source

Mixed function oxygenases in cultured fish cells : contributions of in vitro studies to the understanding of MFO induction

, 1995
publishe
Segner, Helmut, Hauck, Christof R., Braunbeck, Thomas, Scholz, Stefan   +3 more
core  

Preimaginal development of Aedes aegypti L. (Diptera: Culicidae) in brackish water gives rise to adult mosquitoes with thicker cuticles and greater insecticide resistance

Medical and Veterinary Entomology, EarlyView.
The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan, Andrew Hemphill, S. H. P. Parakrama Karunaratne, Arunasalam Naguleswaran, Isabel Roditi, Sinnathamby N. Surendran, Ranjan Ramasamy   +6 more
wiley   +1 more source

Recombinant Saccharomyces cerevisiae expressing P450 in artificial digestive systems : A model for biodetoxication in the human digestive environment [PDF]

, 2003
The use of genetically engineered microorganisms such as bacteria or yeasts as live vehicles to carry out bioconversion directly in the digestive environment is an important challenge for the development of innovative biodrugs.
Marol-Bonnin, S., Meunier, J.P., Minekus, M., Blanquet, S., Alric, M.   +4 more
core  

Thioredoxin system modulates metabolic and stomatal responses to elevated CO2 in Arabidopsis

New Phytologist, EarlyView.
Integrative model of extraplastidial NADPH‐dependent thioredoxin reductase/thioredoxin system‐mediated regulation of stomatal function, redox homeostasis, and metabolic responses under ambient and elevated CO2 in Arabidopsis thaliana. Summary The NADPH‐dependent thioredoxin reductase/thioredoxin (NTR/TRX) system plays a central role in maintaining ...
Paula da Fonseca‐Pereira, Domingos F. Mélo Neto, Rita de Cássia Monteiro‐Batista, Daniel Gomes Coelho, Jaciara Lana‐Costa, Leonardo Perez de Souza, Ina Krahnert, Danilo M. Daloso, Jorge Gago, Alisdair R. Fernie, Wagner L. Araújo, Adriano Nunes‐Nesi   +11 more
wiley   +1 more source

Síntese, caracterização e reatividade de novos complexos de ferro e cobre como modelos para hemeretrina, anidrase carbônica e catecol oxidase [PDF]

, 2001
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Curso de Pós-Graduação em QuímicaA síntese de um novo ligante não simétrico HTPPNOL é apresentada.
Fernandes, Christiane
core