Results 101 to 110 of about 31,380 (219)

Better 10‐Year Cerebrovascular Outcome After Transplant Than on Standard‐Care in Sickle Cell Anemia: DREPAGREFFE Trial

American Journal of Hematology, Volume 101, Issue 8, Page 1799-1817, August 2026.
ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin, Suzanne Verlhac, Elisabeth Ducros‐Miralles, Cécile Arnaud, Isabelle Genty, Marie Petras, Catherine Paillard, Gonzalo De Luna, Benoit Meunier, Isabelle Thuret, Annie Kamdem, Corinne Pondarré, Giovanna Cannas, Christelle Chantalat‐Auger, Nadia Firah, Sophie Pertuisel, Laure Joseph, Florence Missud, Mariane de Montalembert, Corinne Guitton, Claire Pluchart, Valentine Brousse, Monique Elmaleh, Vincent Gajdos, Emmanuella Leveillé, Ekaterina Belozertseva, Mabel Gaba, Catherine Poirot, Virginie Barraud‐Lange, Philippe Chadebech, France Pirenne, Myriam Bernaudin, Bénédicte Neven, Pierre Frange, Marie Angoso, Karima Yakouben, Bénédicte Bruno, Nathalie Dhédin, Jean‐Hugues Dalle, Regis Peffault Delatour, Camille Jung   +40 more
wiley   +1 more source

A Therapeutic Dilemma: Catastrophic ST‐Elevation Myocardial Infarction Following Antiplatelet Therapy Interruption in a Patient With JAK2‐Positive Polycythemia Vera

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Premature interruption of dual antiplatelet therapy in a patient with polycythemia vera and clinically suspected acquired von Willebrand syndrome triggered catastrophic recurrent stent thrombosis, whereas perioperative bridging with eptifibatide enabled safe surgery. ABSTRACT Polycythemia vera is associated with a thrombotic–hemorrhagic paradox.
Behrouz zarei, Amirhossein Rezaei Latifi, Mohammad Salari   +2 more
wiley   +1 more source

Clinical methemoglobinemia secondary to administration of hydroxyurea at therapeutic doses in a dog

Journal of Veterinary Internal Medicine
Methemoglobinemia secondary to administration of hydroxyurea is only reported in veterinary medicine as a result of accidental ingestion of high doses, and once at therapeutic dose in human medicine.
Manon Rigot, Shane W. Bateman, Xiu Ting Yiew   +2 more
doaj   +1 more source

Acute and Chronic Leukemia in Sub‐Saharan Africa: A Systematic Review

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background The four primary subgroups of leukemia include chronic myeloid leukemia (CML), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). Very little is known about the regional variation of leukemia and subtypes in sub‐Saharan Africa (SSA).
Allwell A. Ayirebi, Stephen Twumasi, Linda K. Olaga, Benedict Sackey, Daniel N. M. Antonio, Richard O. Ansah, Eugene A. Ansah, John A. Sah, Enoch O. Anto, Yvonne Anang‐Quartey, Antoinette Koomson, Angela Opoku, Godfred A. Donkor, Paulina Duah, Ama G. Boadu, Samuel Essien‐Baidoo, Wina I. O. Boadu, Lilian A. Boateng   +17 more
wiley   +1 more source

Hydroxyurea

Journal of Biological Chemistry, 1967
Roger L.P. Adams, J.G. Lindsay
openaire   +1 more source

Simultaneous Leukocytapheresis and Continuous Renal Replacement Therapy for Acute Myeloid Leukemia: A Case Report

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT Hyperleukocytosis in acute myeloid leukemia (AML) could cause life‐threatening complications, including leukostasis and tumor lysis syndrome (TLS). While leukocytapheresis and continuous renal replacement therapy (CRRT) are typically performed independently to maintain hemodynamic stability and manage anticoagulation, their simultaneous ...
Seung Hee Cho, Dong Wook Jekarl, Yoo‐Jin Kim, Hyung Suk Cho, Su Kyung Jeon, Hye Young Kim, Inae Park, Eun Jin Kim   +7 more
wiley   +1 more source

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

American Journal of Hematology, Volume 101, Issue 9, Page 2430-2434, September 2026.
Ferras Alashkar, Robert Hable, Denise Zwanziger, Friederike Poppenborg, Raina Yamamoto, Hans Christian Reinhardt, Alexander Röth, Victor Herbst, Yara Bestmann, Marco Kai, Jürgen E. Scherberich   +10 more
wiley   +1 more source

A Personalized, Rate‐of‐Rise (ROR)–Driven Model to Optimize Red Cell Exchange Interval in Chronic Sickle Cell Management

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT Chronic automated red blood cell exchange (RCE) is a cornerstone therapy for preventing sickle cell disease (SCD)‐related complications, particularly stroke and recurrent vaso‐occlusive crises. Current scheduling commonly relies on uniform empirical intervals of 3–6 weeks and does not account for substantial inter‐patient variability in ...
Menatalla Nadim, Austin Choi, Nicholas Parisi, Yamac Akgun   +3 more
wiley   +1 more source

Evaluation of The Use of Hydroxyurea in Treating Children With Sickle Cell Anemia in Central Africa's Rural Area

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background Sickle cell anemia (SCA) is highly prevalent in Central Africa. This disease causes severe manifestations in children, requiring treatment. Hydroxyurea (HU) is currently the most effective treatment for SCA. We evaluated the use of HU in children living in rural Central Africa.
Gloire Mbayabo, Paul Lumbala Kabuyi, Mamy Ngole, Aimé Lumaka, Valerie Race, Gert Matthijs, Tite Mikobi Minga, Koenraad Devriendt, Chris Van Geet, Prosper Tshilobo Lukusa   +9 more
wiley   +1 more source

Successfully performed video capsule endoscopy in an 8‐month‐old infant weighing 7.5 kg

JPGN Reports, Volume 7, Issue 3, Page 474-476, August 2026.
Abstract Video capsule endoscopy (VCE) is a well‐established diagnostic tool for examining the small bowel. Limited data exist on its use in infants. To our knowledge, we present the first detailed case of a successful PillCam®SB3‐VCE performed in an 8‐month‐old infant weighing 7.5 kg with suspected small bowel bleeding following allogeneic ...
Paul‐Christoph Zeisler, Robert Thimme, Ulrike Teufel‐Schaefer, Michael Schultheiß   +3 more
wiley   +1 more source