Results 11 to 20 of about 31,287 (200)
Acta Societatis Botanicorum Poloniae, 2015 Hydroxyurea treatment of onion roots induced mitotic block which was released by transfer of bulbs to water, and also to some extent by addition of cold or 3H-thymidine to hydroxyurea solutions.
H. Habdas
doaj +1 more source
Turkish Journal of Hematology, 2020 Objective: This study aimed to evaluate real-life data on patterns of hydroxyurea prescription/use in polycythemia vera (PV). Materials and Methods: This retrospective chart review study included PV patients who had received hydroxyurea therapy for at ...
Yahya Büyükaşık +20 more
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Frontiers in Pharmacology, 2022 Hydroxyurea has long been used for the treatment of sickle cell anemia (SCA), and its clinical effectiveness is related to the induction of fetal hemoglobin (HbF), a major modifier of SCA phenotypes.
Rahyssa Rodrigues Sales +5 more
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JMIR Research Protocols, 2020 BackgroundHydroxyurea prevents disease complications among patients with sickle cell disease (SCD). Although its efficacy has been endorsed by the National Health Lung and Blood Institute evidence-based guidelines, its adoption is low, both by patients ...
Hankins, Jane S +17 more
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Health and Quality of Life Outcomes, 2017 Background Sickle cell disease (SCD) patients have impaired domains of health-related quality of life (HRQOL). Hydroxyurea is safe and efficacious in SCD; however, adherence is suboptimal, and patients’ perceptions are poorly understood amongst ...
Sherif M. Badawy +5 more
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Haematologica, 2017 Hematocrit control below 45% is associated with a lower rate of thrombosis in polycythemia vera. In patients receiving hydroxyurea, this target can be achieved with hydroxyurea alone or with the combination of hydroxyurea plus phlebotomies.
Alberto Alvarez-Larrán +28 more
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Cells, 2021 Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with a dismal prognosis. Here, we show how an inhibition of de novo dNTP synthesis by the ribonucleotide reductase (RNR) inhibitor hydroxyurea and an inhibition of epigenetic ...
Alexandra Nguyen +5 more
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Hydroxyurea associated ileocecal valve ulcer: evidence for causality [PDF]
Intestinal Research, 2021 Hydroxyurea is an antimetabolite drug that is commonly used in many hematological disorders. Ulcer formation in the gastrointestinal tract is a rare phenomenon associated with this drug.
Thevaraajan Jayaraman +3 more
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Studies with Hydroxyurea VII. Hydroxyurea and the Synthesis of Functional Proteins [PDF]
Journal of Bacteriology, 1967 Hydroxyurea affected neither the synthesis nor the degradation of bacterial messenger-ribonucleic acid. The proteins made by hydroxyurea-treated cells were structurally intact and fully functional. Since the expression of the lethal action of hydroxyurea requires active protein production, the data indicate that treated cells do not die as the result ...
H S, Rosenkranz +4 more
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Photodermatosis secondary to hydroxyurea [PDF]
BMJ Case Reports, 2014 A middle aged Southeast-Asian man, recently diagnosed with chronic myeloid leukaemia (Philadelphia positive on FISH), was started on cytoreductive therapy with hydroxyurea due to high leucocyte count (130 000/µL). The patient had no history of using any other drugs simultaneously or in the recent/remote past. He developed a clearly defined erythematous
Uday, Yanamandra +3 more
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