Results 181 to 190 of about 1,419,907 (265)

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

The FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas, Maria Pitou, Amalia Aggeli, Sotiris Varlamis, Theodora Choli‐Papadopoulou   +4 more
wiley   +1 more source

When Leadership Is Denied: A Phenomenological Study of Women's Lived Experiences of Promotion Rejection in the Pakistani Fashion Industry

Gender, Work &Organization, EarlyView.
ABSTRACT Despite the growing presence of women in creative and leadership roles within the fashion industry, many continue to face barriers to leadership progression. Leadership rejection remains a critical yet underexplored experience that can significantly affect women's professional identity and aspirations.
Atif Bilal, Faiza Majid, Shumaila Zeb, Saqlain Raza, Aliya Abdul Hayee, Wali Ur Rehman   +5 more
wiley   +1 more source

Psychosocial Harm as an Inequality Regime at Work: Intersectional Accounts From Portugal

Gender, Work &Organization, EarlyView.
ABSTRACT This article examines psychosocial harm at work as a sociological problem of inequality rather than only an issue of individual stress. Drawing on Acker's concept of inequality regimes together with minority stress and intersectionality, and based on 60 in‐depth interviews with workers in Portugal, it analyses how overload, insecurity, work ...
Iara Teixeira, Felipe Alckmin‐Carvalho, Guilherme Welter Wendt, Jóni Ledo, Henrique Pereira   +4 more
wiley   +1 more source

The Pen is Mightier Than the Algorithm? A Multilevel Linguistic Comparison of LLM‐ and Human‐Translated Research Article Abstracts

International Journal of Applied Linguistics, EarlyView.
ABSTRACT Translating local research into English as a lingua franca (ELF) connects local scholarship with global readership, but this process remains constrained by language barriers. Large language models (LLMs) offer advanced accessible solutions, but their responsible integration into academic translation requires a deeper understanding of the ...
Yueyue Huang, Yao Yao, Dechao Li
wiley   +1 more source

Underwater Robots and Key Technologies for Operation Control. [PDF]

Cyborg Bionic Syst
Sun L, Wang Y, Hui X, Ma X, Bai X, Tan M.   +5 more
europepmc   +1 more source

A unified formulation for home healthcare routing and scheduling problems

International Transactions in Operational Research, EarlyView.
Abstract Home Healthcare is an essential component of healthcare systems, where caregivers visit patients' homes to deliver services. While presenting advantages with respect to institutional care, such as being cost‐effective and alleviating family burdens, it presents challenges in scheduling and routing caregivers efficiently.
Sara Ceschia, Francesca Da Ros, Luca Di Gaspero, Simona Mancini, Vittorio Maniezzo, Roberto Montemanni, Roberto Maria Rosati, Andrea Schaerf   +7 more
wiley   +1 more source

LRRT*: A robotic arm path planning algorithm based on an improved Levy flight strategy with effective region sampling RRT. [PDF]

PLoS One
Gu Y, Luo H, Gong W, Jiang Y, Yuan T, Cao L, Li H, Zhang W.   +7 more
europepmc   +1 more source

The Rhythmic and the Metronomic: On Charlie Chaplin's Gait

Critical Quarterly, EarlyView.
Matthew Beaumont
wiley   +1 more source

Legacies and Ruptures: Europe's Future in a New (?) Era of Geopolitical Uncertainty

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Europe finds itself adrift in a world of rising geopolitical uncertainty. Russia has brought interstate war back to Europe. American democracy and hegemony and the ‘liberal international order’ appear to be in steep decline. The world as Europeans and Americans have known it for 80 years may be gone forever.
Mark Copelovitch
wiley   +1 more source