Results 121 to 130 of about 219,244 (264)

Real‐time biosensing of Parkinson's disease biomarkers via NIR‐activated upconversion nanoparticles

open access: yesBMEMat, EarlyView.
Schematic illustration of the luminescence resonance energy transfer‐driven core‐shell‐shell UCNPs (cssUCNPs@Fluo4) nanoprobe for simultaneous monitoring of Ca²⁺‐temperature dynamics in Parkinson's disease models. Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with incompletely understood pathophysiology, necessitating ...
Jialin Liu   +9 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

Hyperactivity.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981
'Hyperactivity' has many causes in childhood, and an analytical approach is necessary before management can be applied. In order to be effective, management must be individually tailored. It may take the form of simple adjustments in the child's environment, the treatment of physical illness, emotional support, counselling of parents, or, in selected ...
openaire   +1 more source

Glycosylated dendrimer nanoamplifiers hijack DNA damage‐immune crosstalk for enhanced dual‐track therapy of orthotopic glioblastoma

open access: yesBMEMat, EarlyView.
A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song   +10 more
wiley   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

Hiperatividade: doença ou essência um enfoque da gestalt-terapia

open access: yesPsicologia: Ciência e Profissão
Este trabalho discute a hiperatividade considerando a metáfora do corpo da criança e o seu funcionamento psicológico, de forma a esclarecer se a sua expressão constitui doença ou um modo próprio de ser.
Sheila Antony, Jorge Ponciano Ribeiro
doaj  

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