Arthritis &Rheumatology, EarlyView.Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes +10 more
wiley +1 more source
Linkage of kynurenine pathway metabolites to neuroinflammation in drug-naive children with attention-deficit/hyperactivity disorder: A cross-sectional, case-control study. [PDF]
World J Clin PediatrÜnal K +4 more
europepmc +1 more source
Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression
Arthritis &Rheumatology, EarlyView.Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar +6 more
wiley +1 more source
Establishing clinically important differences in adults with attention deficit/hyperactivity disorder. [PDF]
Gen PsychiatrFu Z +7 more
europepmc +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Although Takayasu's arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B‐cell activation and its contributions to TAK pathogenesis.
Chenglong Fang +10 more
wiley +1 more source
Effectiveness of different digital interventions on symptoms for children and adolescents with attention-deficit/hyperactivity disorder: a network meta-analysis. [PDF]
Front PsychiatryMei J, Zhang W, Bin J.
europepmc +1 more source
Refining Shoulder Diagnostics: A Technical Note on Scapular Physical Examination
Arthroscopy Techniques, EarlyView.Abstract Normal scapulothoracic function relies on a delicate balance among several periscapular muscles and is essential for shoulder motion. Disturbance in this balance can lead to abnormal motion, which can impair shoulder function, leading to pain and discomfort.
Farah Selman +4 more
wiley +1 more source
Maternal Diabetes and Attention Deficit/Hyperactivity Disorder Association: A Narrative Review on Emerging Evidence, Research Gaps and Future Directions. [PDF]
Int J Gen MedZhao C, Liu Y.
europepmc +1 more source
Autism Research, EarlyView.ABSTRACT Youth with autism spectrum disorder or attention‐deficit/hyperactivity disorder (ADHD) may face barriers to sexual and reproductive health (SRH) services. Yet, data on preventive SRH service use remain limited, especially digital care. This population‐based registry study investigated whether patterns of SRH service use differed by digital ...
Lovisa Hellsten +6 more
wiley +1 more source
Toward a Rigorous Framework for Studying the Gut-Brain Axis, Environmental Exposures, and Attention-Deficit/Hyperactivity Disorder. [PDF]
Biol Psychiatry Glob Open SciGur TL.
europepmc +1 more source