Results 61 to 70 of about 4,528 (185)

Brimonidine Therapy for Protection From Noise‐Induced Hearing Loss

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
In this study, we demonstrate that brimonidine protects against noise‐induced hearing loss in young mice by suppressing glutamate synthesis and vesicle transport, thereby reducing excitotoxicity and preserving synaptic integrity. Such early intervention may prevent age‐related hearing loss, highlighting brimonidine's potential as a therapeutic agent ...
Jing Cai   +10 more
wiley   +1 more source

Exploring the Neural Substrates of Number Sense: A Perspective on Genetics, Behaviour and Neural Circuity

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 8, April 2026.
Numerical cognition arises from conserved mechanisms linking genes, neural circuits and behaviour. Using zebrafish as a tractable model, behavioural assays, whole‐brain imaging and genetic analyses can be integrated to identify neural and molecular bases of quantity discrimination. This framework provides a platform for studying numerical cognition and
Mirko Zanon   +3 more
wiley   +1 more source

Current Recommendations for the Use of Sound Therapy in Adults with Hyperacusis: A Scoping Review

open access: yes
Hyperacusis is a condition that is characterized by hypersensitivity to normal everyday sounds or reduced sound tolerance and can affect patients in distressing ways. Sound therapy is a treatment intervention that is used to desensitize patients. However,
El Nsouli, Dayana   +7 more
core   +1 more source

Association between sleep disorders, hyperacusis and tinnitus: Evaluation with tinnitus questionnaires

open access: yesNoise and Health, 2013
Patients with tinnitus are heterogeneous and several factors influence the impact of this symptom on the quality of life. The aim of the study is to evaluate the relationship between age, gender, sleep disorders, hyperacusis and tinnitus annoyance and to
Alessandra B Fioretti   +2 more
doaj   +1 more source

Selective Disruption of Salience‐Network Anterior Insula Connectivity in Misophonia: A Disorder‐Specific Neural Signature

open access: yesHuman Brain Mapping, Volume 47, Issue 3, 15 February 2026.
Using resting‐state functional connectivity in a large sample of adults from the general population, our results provide neural evidence that misophonia is a discrete spectrum disorder (separate from anxiety, depression, and autism) and has a characteristic neural signature of salience insular connectivity. ABSTRACT Misophonia, a disorder characterized
Heather A. Hansen   +4 more
wiley   +1 more source

Hyperacusis among adults with occupational noise exposure [PDF]

open access: yes
Introduction: Hyperacusis is an increased sensitivity and reduced tolerance to sounds at an acceptable level for most people. This research effort addresses this critical gap in understanding the role of occupational workers as one of the contributing ...
Mat Nasir, Nurul Lydia Nazifa   +2 more
core   +1 more source

Prevalence and Characteristics of Patients with Severe Hyperacusis among Patients Seen in a Tinnitus and Hyperacusis Clinic.

open access: yes, 2018
PURPOSE: The purpose was to assess the proportion of patients seeking help for tinnitus and/or hyperacusis who have severe hyperacusis and to examine factors associated with severe hyperacusis.
Hashir Aazh, Brian C. J. Moore
core   +2 more sources

Efficacy and Safety of Intratympanic Botulinum Toxin Injection on Middle Ear Myoclonic Tinnitus

open access: yesThe Laryngoscope, Volume 136, Issue 1, Page 403-410, January 2026.
Intratympanic Botulinum toxin (IT‐BTX) injection appears to be an effective and safe treatment for MEMT, significantly reducing tinnitus‐related symptoms without complications. In a retrospective study of 57 patients, THI scores and VAS measures for loudness, awareness, annoyance, and life impact improved significantly over 6 months.
Ji Hyung Lim   +8 more
wiley   +1 more source

Pontine Hemorrhage Mimicking Bell’s Palsy: Isolated Facial Nerve Palsy—A Case Report

open access: yesCase Reports in Neurological Medicine, Volume 2026, Issue 1, 2026.
Bell’s palsy, the most common cause of idiopathic peripheral facial palsy, is typically attributed to viral reactivation; however, rare cases due to cerebrovascular disease must always be considered in the differential diagnosis. We report the case of a 75‐year‐old man with poorly controlled hypertension, diabetes mellitus, and a history of smoking who
Rei Takeichi   +5 more
wiley   +1 more source

Hyperacusis clinical audiology practice patterns (Jahn & Koach, 2023)

open access: yes, 2023
Purpose: Hyperacusis often leads to debilitating psychosocial consequences, but there is no standard protocol for its diagnosis and management in the United States. In this study, we surveyed U.S.
Chelsea E. Koach (17277876)   +1 more
core   +1 more source

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