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Treatment of primary hyperaldosteronism.
Medicina Clínica (English Edition), 2020Primary aldosteronism is associated with higher cardiovascular and renal morbidity and mortality than essential hypertension in age- and sex-matched patients with the same degree of blood pressure elevation. Therefore, it is essential to establish a specific treatment to avoid the deleterious effects of aldosterone excess.
M. Araujo-Castro
semanticscholar +4 more sources
The cardiovascular consequences of hyperaldosteronism.
Annales d'Endocrinologie, 2020Primary aldosteronism (PA), the most common form of secondary hypertension, has been considered for decades as a "benign" form of hypertension, but evidences progressively built up to show that patients with PA had an excess rate of cardiovascular damage as compared to blood pressure-matched essential hypertensive patients.
G. Rossi +3 more
semanticscholar +4 more sources
Catheterization and cardiovascular interventions, 2021
This study aimed to assess the safety, blood pressure changes, and biochemical responses of superselective adrenal artery embolization (SAAE) in hypertensive patients with idiopathic hyperaldosteronism (IHA).
H. Dong +8 more
semanticscholar +1 more source
This study aimed to assess the safety, blood pressure changes, and biochemical responses of superselective adrenal artery embolization (SAAE) in hypertensive patients with idiopathic hyperaldosteronism (IHA).
H. Dong +8 more
semanticscholar +1 more source
Finerenone - Halting Relative Hyperaldosteronism in Chronic Kidney Disease.
New England Journal of Medicine, 2020Type 2 diabetes is the most common cause of chronic kidney disease (CKD) and end-stage renal disease.
J. Ingelfinger, C. Rosen
semanticscholar +1 more source
Endocrine Practice, 1997
To characterize the syndrome of primary aldosteronism and summarize diagnostic and therapeutic strategies.We review the mechanisms of action of aldosterone and outline features that distinguish the major subtypes of aldosteronism.The state of aldosterone excess should be suspected in every patient manifesting hypertension and hypokalemia.
M T, Laurel, U M, Kabadi
openaire +2 more sources
To characterize the syndrome of primary aldosteronism and summarize diagnostic and therapeutic strategies.We review the mechanisms of action of aldosterone and outline features that distinguish the major subtypes of aldosteronism.The state of aldosterone excess should be suspected in every patient manifesting hypertension and hypokalemia.
M T, Laurel, U M, Kabadi
openaire +2 more sources
The Journal of Steroid Biochemistry and Molecular Biology, 2001
Primary aldosteronism (PAL) may be as much as ten times more common than has been traditionally thought, with most patients normokalemic. The study of familial varieties has facilitated a fuller appreciation of the nature and diversity of its clinical, biochemical, morphological and molecular aspects.
Stowasser, Michael, Gordon, Richard D.
openaire +3 more sources
Primary aldosteronism (PAL) may be as much as ten times more common than has been traditionally thought, with most patients normokalemic. The study of familial varieties has facilitated a fuller appreciation of the nature and diversity of its clinical, biochemical, morphological and molecular aspects.
Stowasser, Michael, Gordon, Richard D.
openaire +3 more sources
Medical Clinics of North America, 1988
Primary hyperaldosteronism is a challenging diagnosis because of its low incidence and variable pathophysiology. Serum potassium, properly done, is the routine screening test, but is not without its limitations. Confirmation of the diagnosis requires demonstration of abnormally high and nonsuppressible values for aldosterone in plasma and urine and low
R H, Noth, E G, Biglieri
openaire +2 more sources
Primary hyperaldosteronism is a challenging diagnosis because of its low incidence and variable pathophysiology. Serum potassium, properly done, is the routine screening test, but is not without its limitations. Confirmation of the diagnosis requires demonstration of abnormally high and nonsuppressible values for aldosterone in plasma and urine and low
R H, Noth, E G, Biglieri
openaire +2 more sources
Diabetes in Hyperaldosteronism
2014Primary aldosteronism (PA) is the most common cause of endocrine hypertension. PA is a heterogeneous disease, which can be divided into various different subtypes. The mechanisms through which aldosterone exerts an effect on glucose and insulin metabolism are different.
Crudo V +3 more
openaire +3 more sources
Experimental and Clinical Endocrinology & Diabetes, 2002
Primary hyperaldosteronism (PHA) is regarded as a rare disease with prevalence rates of 0.5 to 2% within the hypertensive population. Recent studies using more detailed screening procedures in small hypertensive cohorts have suggested that PHA may be more common than previously thought (3-18%).
M, Quinkler, J, Lepenies, S, Diederich
openaire +2 more sources
Primary hyperaldosteronism (PHA) is regarded as a rare disease with prevalence rates of 0.5 to 2% within the hypertensive population. Recent studies using more detailed screening procedures in small hypertensive cohorts have suggested that PHA may be more common than previously thought (3-18%).
M, Quinkler, J, Lepenies, S, Diederich
openaire +2 more sources