The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine. [PDF]
Yang Y +10 more
europepmc +1 more source
Heparin and rat brain heparin-binding proteins take part in the process of hyperalgesia [PDF]
Г. А. Ушакова +2 more
openalex +1 more source
Objective To assess the efficacy and safety of Chaihu‐Guizhi‐Ganjiang decoction (CGGJD) combined with Danggui‐Shaoyao‐San (DS) in oligomenorrhea treatment. Methods In this prospective open‐label trial, 35 oligomenorrhea patients (30–40 years) received CGGJD‐DS for 3 months, followed by a 2‐month follow‐up.
Mei Yu +5 more
wiley +1 more source
Effects of different anesthetics on remifentanil-induced postinfusion hyperalgesia in patients undergoing percutaneous endoscopic interlaminar discectomy: a randomized controlled trial. [PDF]
Ba Y, Wang Y, Dai L, Yang S.
europepmc +1 more source
Advanced cancer continues to pose a substantial global challenge, with complex symptom burdens and limited therapeutic options. Traditional Chinese Medicine (TCM), grounded in holistic theory and the principles of syndrome differentiation, employs interventions such as herbal medicine, acupuncture, moxibustion, and acupoint‐based therapies to address ...
Chunmeng Jiao +6 more
wiley +1 more source
Myricetin Attenuates Hyperexcitability of Trigeminal Nociceptive Second-Order Neurons in Inflammatory Hyperalgesia: Celecoxib-like Effects. [PDF]
Yamaguchi S, Takeda M.
europepmc +1 more source
Acidic Saline-Induced Primary and Secondary Mechanical Hyperalgesia in Mice
Neena K. Sharma +4 more
openalex +1 more source
Peripheral neuropathic pain (PNP), a chronic condition resulting from nerve damage and characterized by altered sensory signaling and central sensitization, poses significant therapeutic challenges. Botulinum toxin (BTX), known for neuromuscular blockades, also exhibits analgesic properties, prompting its investigation for PNP management.
Domenico Antonio Restivo +5 more
wiley +1 more source
Ventral Anterior-Lateral Complex of the Thalamus Mediates Chronic Stress-Induced Pain Hypersensitivity and Underlies Electroacupuncture Analgesia. [PDF]
Chen J +5 more
europepmc +1 more source
Current research hotspots and difficulties of chronic prostatitis/chronic pelvic pain syndrome: neuroendocrine mechanism. [PDF]
Shao B +8 more
europepmc +1 more source

