Results 131 to 140 of about 15,555 (178)
Some of the next articles are maybe not open access.
Pharmacotherapy for hyperammonemia
Expert Opinion on Pharmacotherapy, 2014Hepatic encephalopathy (HE) is a serious neuropsychiatric complication that is seen in patients with liver failure. The pathogenesis of HE is not entirely understood, but several hypotheses have emerged and persisted during the years. Despite the many prevalent hypotheses, most of the existing evidence point to ammonia as the main culprit behind ...
Anna, Hadjihambi +2 more
openaire +2 more sources
Valproate‐induced hyperammonemia
Annals of Neurology, 1982AbstractA patient with carbamyl phosphate synthetase deficiency had four episodes of hyperammonemia, up to 226 μM, associated with valproate (VPA) treatment. These were accompanied by vomiting, lethargy, and coma. A group of epileptic patients receiving VPA remained asymptomatic but had significantly higher mean plasma ammonium levels when compared to ...
M L, Batshaw, S W, Brusilow
openaire +2 more sources
Pediatrics, 1980
Goldberg et al1 described 12 infants with hyperammonemia in association with severe perinatal asphyxia, characterized by low Apgar scores and prolonged resuscitation, in premature, term, and postmature neonates. Ballard and colleagues2 reported five preterm infants with transient hyperammonemia and respiratory distress. We wish to summarize briefly the
Sherida E. Tollefsen +2 more
openaire +1 more source
Goldberg et al1 described 12 infants with hyperammonemia in association with severe perinatal asphyxia, characterized by low Apgar scores and prolonged resuscitation, in premature, term, and postmature neonates. Ballard and colleagues2 reported five preterm infants with transient hyperammonemia and respiratory distress. We wish to summarize briefly the
Sherida E. Tollefsen +2 more
openaire +1 more source
Clinical Chemistry and Laboratory Medicine, 2002
Hyperammonemia is mainly found in hepatic encephalopathy and in genetic defects of the urea cycle or other pathways of the intermediary metabolism. Clinically a difference has to be made between chronic moderate hyperammonemia and acutely increased concentrations. Pathogenetic mechanisms of ammonia toxicity to the brain are partly unraveled.
openaire +2 more sources
Hyperammonemia is mainly found in hepatic encephalopathy and in genetic defects of the urea cycle or other pathways of the intermediary metabolism. Clinically a difference has to be made between chronic moderate hyperammonemia and acutely increased concentrations. Pathogenetic mechanisms of ammonia toxicity to the brain are partly unraveled.
openaire +2 more sources
Hyperammonemia in Multiple Myeloma
Acta Haematologica, 1990Two patients with multiple myeloma who appeared to be producing ammonia are reported. Both patients showed hyperammonemia and amino acid disturbances, such as a low Fischer ratio. One patient had Bence Jones protein (lambda) type myeloma and became comatose, but the hyperammonemia and disturbance of consciousness were improved by chemotherapy for the ...
H, Matsuzaki +6 more
openaire +2 more sources
Hyperammonemia: The Silent Killer
Southern Medical Journal, 1993Nitrogen, derived from breakdown of dietary amino acids as ammonia, is normally converted to urea and excreted. Impairment in the conversion process (called the urea cycle) can occur, either as a consequence of primary genetic defects or through secondary suppression of enzyme activity.
D E, Miga, K S, Roth
openaire +2 more sources
Pediatrics In Review, 1984
Neonatal hyperammonemia is a life-threatening complication of several conditions seen in the newborn infant (Table 1). Some of these disorders are potentially reversible; others are amenable to long-term therapy if early diagnosis and aggressive management in the neonatal period can prevent the catastrophic neurologic deterioration that accompanies ...
Steven M. Donn, Raul C. Banagale
openaire +1 more source
Neonatal hyperammonemia is a life-threatening complication of several conditions seen in the newborn infant (Table 1). Some of these disorders are potentially reversible; others are amenable to long-term therapy if early diagnosis and aggressive management in the neonatal period can prevent the catastrophic neurologic deterioration that accompanies ...
Steven M. Donn, Raul C. Banagale
openaire +1 more source
Hyperammonemia in Alzheimer's disease
American Journal of Psychiatry, 1985Postprandial blood ammonia levels were significantly higher in 22 patients with Alzheimer's disease than in 37 control subjects. In the Alzheimer group, fasting blood ammonia levels were significantly higher in patients whose EEGs showed triphasic waves than in patients without this change.
M, Fisman +5 more
openaire +2 more sources
Severe Transient Neonatal Hyperammonemia
American Journal of Perinatology, 1986Severe transient hyperammonemia is a disorder of unknown etiology which can be successfully treated. This article describes two infants affected by this condition and reviews the pertinent literature. Forty-nine cases, including our own, are summarized.
G P, Giacoia, A, Padilla-Lugo
openaire +2 more sources
Iatrogenic Hyperammonemia After Anorexia
Archives of Internal Medicine, 2010High-protein dietary supplements were started for 2 patients, who had a period of anorexia before hospital admission but no history of liver disease. Subsequent altered mental status with ataxia developed in both patients. After excluding other causes, hyperammonemia was noted, while liver function test results remained normal.
Emily, Welsh +2 more
openaire +2 more sources