Results 151 to 160 of about 58,406 (311)

Determination and evaluation of clinically efficient stopping criteria for the multiple auditory steady-state response technique [PDF]

open access: yes, 2009
Background: Although the auditory steady-state response (ASSR) technique utilizes objective statistical detection algorithms to estimate behavioural hearing thresholds, the audiologist still has to decide when to terminate ASSR recordings introducing ...
D'Haenens, Wendy   +2 more
core   +1 more source

A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Sujan Tamang   +6 more
wiley   +1 more source

A note on the prothrombin time abnormality in the patients with amebic liver abscess [PDF]

open access: yes, 2006
Amebic liver abscess is reported worldwide and can present with a a wide spectrum of clinical manifetations. Similar to the other liver diseases, the prothrombin time abnormality can be seen in the patients with amebic liver abscess.
Suwansaksri, Jamsai   +2 more
core   +1 more source

Identification of Genetic Risk Factors for Neonatal Hyperbilirubinemia in Fujian Province, Southeastern China: A Case-Control Study [PDF]

open access: hybrid, 2018
Jinfu Zhou   +8 more
openalex   +1 more source

Stroke as an Initial Presentation of Hepatocellular Carcinoma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Malignancy and ischemic stroke are major causes of global morbidity and mortality. Thromboembolic strokes secondary to malignancy are uncommon but represent a critical consideration in cryptogenic stroke. We report the case of a 46‐year‐old female with no significant past medical history who presented with acute rightward gaze deviation. Brain
Fereydun Moradi   +2 more
wiley   +1 more source

A Technique for Laparoscopic Right Hepatectomy Following Portal Vein Embolization in a Patient With Portal Vein Thrombosis: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Intraoperative findings during laparoscopic right hepatectomy following portal vein embolization. ABSTRACT Laparoscopic right hepatectomy following portal vein embolization remains challenging because of its technical complexity. One possible problem during hepatectomy including portal vein (PV) embolization is PV thrombosis.
Tatsuyuki Shinohara   +3 more
wiley   +1 more source

A Phase 1 Dose‐Escalation, Food Effect, and Drug–Drug Interaction Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MALT1 Inhibitor, SGR‐1505, in Healthy Volunteers

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract SGR‐1505 is a novel small‐molecule inhibitor of MALT1, a key mediator of NF‐κB signaling implicated in the pathogenesis of B‐cell malignancies. This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of SGR‐1505 in healthy volunteers. In this four‐part, open‐label study, 73 participants received single or multiple
Vipul K. Gupta   +16 more
wiley   +1 more source

Safety, Pharmacokinetics, and Pharmacodynamics of Osivelotor for Sickle Cell Disease: First‐in‐Human Studies in Healthy Participants and Patients

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 120-130, January 2026.
The investigational agent osivelotor, a small molecule hemoglobin (Hb) modifier in development for the treatment of sickle cell disease (SCD), acts by increasing Hb‐oxygen affinity and inhibiting the polymerization of sickle Hb. We report safety, pharmacokinetic (PK), and pharmacodynamic (PD) data from the first two phase 1 clinical trials of ...
Eleanor A. Lisbon   +15 more
wiley   +1 more source

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