Results 91 to 100 of about 2,378 (266)

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

Linguistic Means of Intensification and Emphasis in English Promotional Discourse

Дискурс профессиональной коммуникации
This study addresses the strategic use of emphatic means in English promotional discourse, used by automotive manufacturers to underscore the strengths of their premium and top-tier vehicles in a highly competitive global market.
Yu. A. Filyasova
doaj   +1 more source

Giant Magneto‐Optical Effects in Two‐Dimensional Flat‐Band Antiferromagnets

Advanced Science, EarlyView.
RuOCl2${\rm RuOCl}{_2}$, a two‐dimensional antiferromagnet, hosts energy bands with pronounced directional flatness. This study demonstrates that the flat‐band‐induced optical transitions yield strongly anisotropic absorption and a record‐large magneto‐optical Schafer–Hubert effect, alongside exceptional linear dichroism exceeding 50%.
Ping Yang, Wanxiang Feng, Siyuan Liu, Shan Guan, Liwei Wen, Wei Jiang, Gui‐Bin Liu, Yugui Yao   +7 more
wiley   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

CONCEPTUAL INTEGRATION AS A MECHANISM OF DEMOTIVATOR INTERPRETATION

Неофилология, 2016
The demotivator as a multimodal text which synthesizes verbal and visual components and is characterized by multidimensionality, comic sense is analyzed.
Lyudmila Vladimirovna Babina, Anastasiya Sergeevna Ivanova   +1 more
doaj  

POETICS OF THE BASHKIR FOLK EPIC "URAL-BATYR"

Uluslararası Türk Lehçe Araştırmaları Dergisi, 2017
The article is devoted to the study of the poetics of the Bashkir folk epic "Ural-batyr". "Ural-batyr", created by the genius of the people on the basis of ancient mythology, is an invaluable monument not only of Bashkir but also of world culture.
Gölnar YULDIBAYEVA
doaj   +1 more source

Twin‐Lever Multifunctional Meta‐Optics With High Longitudinal Tolerance

Advanced Science, EarlyView.
We introduce a single‐layer, CMOS‐compatible metasurface that allows for polarization‐programmable, achromatic broadband dual‐mode imaging with high longitudinal tolerance. The twin‐lever design combines bright‐field focusing and vortex‐based edge‐enhanced imaging while managing axial intensity distribution from 488 to 633 nm.
Isma Javed, Kyungtae Kim, Aqib Raza Shah, Dohyun Kang, Joohoon Kim, Azhar Javed Satti, Xuefeng Liu, Muhammad Zubair, Jichuan Xiong, Muhammad Qasim Mehmood, Junsuk Rho   +10 more
wiley   +1 more source

Structural Changes and Transport Properties of YBa2Cu3O7 Locally Modified by a He+ Focused Ion Beam

Advanced Science, EarlyView.
The structure and the electric transport properties of YBa2Cu3O7 modified with 30 keV He+${\rm He}^{+}$ ions depend on the irradiation dose and lateral size of the irradiated area, as shown by low‐temperature resistivity measurements, diffraction with a nanofocused X‐ray beam and atomic force microscopy.
Ross Carter, Robin Hutt, Paul Zimmermann, Ainur Abukaev, Jan Ullmann, Simon Koch, Christoph Schmid, Manfred Burghammer, Reinhold Kleiner, Dieter Koelle, Edward Goldobin, Ivan A. Zaluzhnyy   +11 more
wiley   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Fast Programming of in‐Plane Hyperbolic Phonon Polariton Optics through Van der Waals Crystals Using the Phase‐Change Material In3SbTe2

Advanced Science, EarlyView.
Launching structures for in‐plane hyperbolic polaritons in α‐MoO3 are optically programmed through already deposited flakes into the phase‐change material In3SbTe2. Precise alignment with the flake's crystal axes, focusing of polaritons by an optically programmed disk, and a first experimental realization toward a nanocavity for in‐plane hyperbolic ...
Lina Jäckering, Umberto Saldarelli, Aaron Moos, Lukas Conrads, Enrique Terán‐García, Christian Lanza, Aitana Tarazaga Martín‐Luengo, Gonzalo Álvarez‐Pérez, Pablo Alonso‐González, Matthias Wuttig, Thomas Taubner   +10 more
wiley   +1 more source