Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo +4 more
wiley +1 more source
Generation of multi-form exact wave solutions and linear stability analysis in the generalized (3+1)-D P-type plasma system using a modified extended mapping technique. [PDF]
Ghayad MS, Ahmed HM, Badra NM, Rabie WB.
europepmc +1 more source
stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang +3 more
wiley +1 more source
Dynamical study of optical soliton solutions to the Lakshmanan-Porsezian-Daniel equation by using [Formula: see text]-model expansion approach. [PDF]
Alharthi MR +5 more
europepmc +1 more source
Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram +4 more
wiley +1 more source
Delay-Induced Complexity and Chaotic Dynamics in a Network Model of Information Spreading. [PDF]
Martsenyuk V, Gancarczyk T.
europepmc +1 more source
Layer‐Dependent Phonon Polaritons in hBN Resolved by Photo‐Induced Force Spectroscopy
Layer‐dependent phonon polariton resonances in hexagonal boron nitride are systematically investigated using photo‐induced force microscopy. The in‐plane resonance exhibits a blueshift, while the out‐of‐plane resonance shows a redshift with increasing thickness. These results establish layer number as a key parameter for tuning polaritonic responses in
Amin Hajarian, Jiwoo Seo, SungWoo Nam
wiley +1 more source
On the Integration of Hyperbolic Differential Equations [PDF]
openaire +2 more sources
A symbolic dataset for large language models to solve second kind Fredholm integral equations. [PDF]
Dana Mazraeh H +3 more
europepmc +1 more source
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng +7 more
wiley +1 more source

