Data-driven reduced modeling of neural dynamics. [PDF]
Nat CommunMarraffa A, Krause R, Mante V, Haller G.
europepmc +1 more source
Generalized Hyperbolic Distributions and Brazilian Data [PDF]
The aim of this paper is to discuss the use of the Generalized Hyperbolic Distributions to fit Brazilian assets returns. Selected subclasses are compared regarding goodness of fit statistics and distances.
Aquiles Farias, José Fajardo
core
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Policy Effects in Hyperbolic vs. Exponential Models of Consumption and Retirement [PDF]
This paper constructs a structural retirement model with hyperbolic preferences and uses it to estimate the effect of several potential policy changes.
Alan L. Gustman, Thomas L. Steinmeier
core
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Ground Penetrating Radar for Subsurface Utility Detection: Methods, Challenges, and Future Directions. [PDF]
Sensors (Basel)Gao S, Hu D.
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Advanced Science, EarlyView.Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Bias-Aware Detection Limits, Calibration Transfer and Matched-Control Robustness Assessment in Dual-Parameter Photonic Refractive-Index and Temperature Sensing: A Coupled Interface-Mode Multilayer Case Study. [PDF]
Sensors (Basel)Ertay AO, Ertay MM.
europepmc +1 more source
Developing Soft Interconnected Microchannel Network for 2D Skin‐Like Actuator
Advanced Science, EarlyView.A soft interconnected network of microchannels is proposed to develop new pneumatic actuators for future bio‐inspired soft robots. Simultaneous stimulation of this network generates regional asymmetric strains in walls of microchannels whose interaction across the entire surface leads to bending curvatures in multidimensions.
John Noee +4 more
wiley +1 more source