Results 171 to 180 of about 13,449 (301)

Walks with jumps: a neurobiologically motivated class of paths in the hyperbolic plane. [PDF]

J Math Biol
DeBlois J, Einstein E, Victor JD.
europepmc   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

A meta-analysis of neural systems underlying delay discounting: Implications for transdiagnostic research. [PDF]

Imaging Neurosci (Camb)
Lakhani NV, Souther MK, Boateng B, Kable JW.   +3 more
europepmc   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

Advanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet, Priyanka Kumari, Sathyanarayana Paladugu, Damian Pociecha, Jakub Karcz, Przemysław Kula, Nataša Vaupotič, Ewa Górecka, Oleg D Lavrentovich   +8 more
wiley   +1 more source

Frequency-dependent topological polaritons in carbon nanotube array/hBN heterostructures. [PDF]

Nat Commun
Xie Y, Feng K, Zhang Z, Ma S, Wu Z, Chen Y, Zhang C, Wang L, Watanabe K, Taniguchi T, Liang Q, Guo X, Dai Q, Shi Z.   +13 more
europepmc   +1 more source

Perspective: Hollow Core Optical Fibres for Ultraviolet and Visible Wavelengths

Advanced Science, EarlyView.
Hollow core optical fibres bypass material constraints that limit optical fibres at ultraviolet and visible wavelengths. However, their challenging fabrication has limited their development, and significant gains in performance remain possible. In this perspective we outline approaches to enable the next generation of fibres for shorter wavelengths ...
Robbie Mears, Kerrianne Harrington, Jonathan C. Knight, William J. Wadsworth, James M. Stone, Tim A. Birks   +5 more
wiley   +1 more source

Giant Optical Anisotropy and Visible-Frequency Epsilon-near-Zero in Hyperbolic van der Waals MoOCl₂. [PDF]

Nano Lett
Ermolaev G, Toksumakov A, Slavich A, Minnekhanov A, Tselikov G, Mazitov A, Kruglov I, Tikhonowski G, Mironov M, Radko IP, Grudinin D, Fradkin I, Vyshnevyy A, Sofer Z, Arsenin A, Novoselov KS, Volkov V.   +16 more
europepmc   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Tunable Structural Color in Au-Based One-Dimensional Hyperbolic Metamaterials. [PDF]

Nanomaterials (Basel)
Téllez-Limón R, Rodríguez-Beltrán RI, López-Rayón F, Gómez-Robles M, Figueroa-Guardiola K, Chávez-Padua JE, Coello V, Salas-Montiel R.   +7 more
europepmc   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source