Results 161 to 170 of about 15,634 (261)

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

open access: yesAdvanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su   +7 more
wiley   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

open access: yesAdvanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong   +21 more
wiley   +1 more source

Large‐Aperture Polarization‐Independent Broadband Achromatic All‐Dielectric Metalens for Terahertz Focusing

open access: yesAdvanced Science, EarlyView.
A large‐aperture, high focusing efficiency and polarization‐independent THz single‐layer achromatic metalens is reported via discrete multi‐wavelength achromatic design and global optimization algorithm. The fabricated metalens exhibits a largest diameter of 2.21 cm, excellent achromatic performance, extremely high average focusing efficiency (> 46 ...
Xiaoqiang Jiang   +6 more
wiley   +1 more source

Hyperbolic P ( Φ ) 2 -model on the Plane. [PDF]

open access: yesCommun Math Phys
Oh T, Tolomeo L, Wang Y, Zheng G.
europepmc   +1 more source

A Scalable BaTiO3 Nanocoating Strategy for Cost‐Effective and Stable Sulfide‐Based All‐Solid‐State Batteries

open access: yesAdvanced Science, EarlyView.
A rapid and scalable 10 min BaTiO3 (BTO) nanocoating uniformly encapsulates Li‐P‐S‐X sulfide electrolytes, serving as a dielectric “shield” that enhances air stability, reduces cost, and mitigates interfacial degradation. This multifunctional coating enables fast‐charging, durable all‐solid‐state batteries with ultralong cycling stability (>10 000 ...
Wenjin Li   +10 more
wiley   +1 more source

Linking Plant Metabolomics with Fungal Functional Dynamics Reveals a Noncanonical S‐R‐C Adaptive Trajectory

open access: yesAdvanced Science, EarlyView.
Using field‐based holo‐omics, we demonstrate that developmental shifts in sorghum leaf metabolomes drive a noncanonical fungal succession from stress tolerators (S) through ruderals (R) to competitors (C). Antifungal metabolites in young leaves select for S strategists with expanded genomes, transient maltose pulses during flowering favor fast‐growing ...
Peilin Chen, John W. Taylor, Cheng Gao
wiley   +1 more source

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