Results 91 to 100 of about 88,811 (347)

Frequency and prognostic significance of hypercalcemia in patients with multiple myeloma

Medical Journal of Babylon, 2020
Background: Multiple myeloma (MM) is defined as a clonal B-cell malignancy of the bone marrow. Hypercalcemia is associated with cancers in general and in MM specifically becomes more obvious with frequent adverse outcomes. Objectives: The objective is to
Kanar J Karim, Abid M Hassan, Hisham A Getta, Najmaddin S. H. Khoshnaw, Sana D Jalal, Akram M Mohammed, Kawa M Hasan, Dana A Abdullah, Ameer I A. Badi, Ahmed K Yassin, Banaz M Safar, Basil K Abdulla, Rawand P Shamoon, Truska A Amin, Zeki A Mohamed, Ali I Mohammed, Diveen J Hussein, Nawsherwan S Mohammed, Rezhin N Rajab, Firiad Hiwaizi   +19 more
doaj   +1 more source

Thiazide-Associated Hypercalcemia: Incidence and Association With Primary Hyperparathyroidism Over Two Decades.

Journal of Clinical Endocrinology and Metabolism, 2016
CONTEXT Thiazide diuretics, the antihypertensive agent prescribed most frequently worldwide, are commonly associated with hypercalcemia. However, the epidemiology and clinical features are poorly understood.
Marcio L Griebeler, A. Kearns, E. Ryu, P. Thapa, M. Hathcock, L. Melton, R. Wermers   +6 more
semanticscholar   +1 more source

Metastatic intrigue: Penile involvement in prostate cancer with neuroendocrine differentiation—A case report

UroPrecision, EarlyView.
Abstract Background Neuroendocrine carcinoma of the prostate is a rare tumor subtype found in the spectrum of prostate cancer, and is more difficult to detect, due to the low prostate‐specific antigen values associated with it. A high degree of suspicion is hence needed to arrive at the diagnosis in such cases.
Uttam Kumar Mete, Neha Bhardwaj, Radhika Srinivasan, Rohit Sanjay Deshpande   +3 more
wiley   +1 more source

Risk factors for hypercalcemia in patients with tuberculosis

International Journal of Mycobacteriology, 2020
Background: Tuberculosis (TB) is prevalent worldwide and causes significant morbidity and mortality. TB is known to cause hypercalcemia. We aimed to assess the prevalence and risk factors for developing hypercalcemia among patients with TB.
Sujith Mathew John, Sheeba Sagar, Joshi Krishnakumari Aparna, Sharon Joy, Ajay Kumar Mishra   +4 more
doaj   +1 more source

Vitamin D supplementation in the pediatric rheumatology clinic. [PDF]

, 2011
Vitamin D is capturing the attention of healthy and chronically ill populations for its potential skeletal and nonskeletal benefits. New information suggesting a role in immune modulation has led to a surge of interest among rheumatologists. Although the
Burnham, Jon M, von Scheven, Emily
core   +3 more sources

Cinacalcet for Symptomatic Hypercalcemia Caused by AP2S1 Mutations.

New England Journal of Medicine, 2016
The authors show that cinacalcet, which mediates allosteric modulation of the calcium-sensing receptor, corrects loss of function of AP2S1 mutations that cause familial hypocalciuric hypercalcemia type 3 and ameliorates symptomatic hypercalcemia.
S. Howles, F. Hannan, Valerie N. Babinsky, A. Rogers, C. Gorvin, N. Rust, T. Richardson, M. McKenna, M. Nesbit, R. Thakker   +9 more
semanticscholar   +1 more source

Long‐term survival in a dog with suspected primary nodal plasmacytoma treated with surgical excision

Veterinary Record Case Reports, EarlyView.
Abstract An 8‐year‐old Staffordshire bull terrier presented for left submandibular lymphadenopathy. Cytology showed a monomorphic population of mature plasma cells suggestive of plasma cell neoplasia. On physical examination, no other lymphadenomegaly, cutaneous or oral lesions were found.
Celia Figueroa‐González, Jérémy Béguin, Sarah Stewart, Rachel Garty, Alexandra Guillén   +4 more
wiley   +1 more source

The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]

, 2013
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves, D'Herde, Katharina, Diez Fraile, Araceli, Lammens, Tim   +3 more
core   +1 more source

Hypercalcemia in pregnancy – a multifaceted challenge: case reports and literature review

Clinical Case Reports, 2016
Hypercalcemia in pregnancy is an uncommon event that can cause major maternal morbidity and/or fetal or neonatal morbidity and mortality. Management is a challenge for the clinicians, especially as regards to investigations in pregnancy, surgery, and the
E. Rey, C. Jacob, Maral Koolian, F. Morin   +3 more
semanticscholar   +1 more source

Suspected calcitriol‐mediated hypercalcaemia and postmortem diagnosis of histiocytic sarcoma in a dog

Veterinary Record Case Reports, EarlyView.
Abstract This report describes a case of refractory ionised hypercalcaemia, of 12 months duration, in an 11‐year‐old, male, neutered beagle diagnosed with metastatic histiocytic sarcoma at postmortem examination. In this case, the parathyroid hormone levels were at the lower end of the reference interval, the parathyroid hormone‐related peptide was ...
Kerry E. Rolph, Mollie McBride, Gilda Rawlins‐Vaughan, Sarah Cavanaugh, Regina Tose Kemper, Pompei Bolfa   +5 more
wiley   +1 more source