Results 131 to 140 of about 65,906 (319)

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice [PDF]

open access: yes, 2017
Esser, Alison K   +11 more
core   +2 more sources

Sporadic Medullary Microcarcinoma in a Young Patient - A Rare Case [PDF]

open access: yes, 2010
Sporadic medullary microcarcinoma of thyroid is a rare disease detected usually in 0.15% of all thyroid malignancy. We report a case of sporadic medullary microcarcinoma (MMC) of thyroid in a 24 year old male presenting as solitary thyroid nodule.
D, Manjunath   +3 more
core   +1 more source

A Proof‐of‐Concept Phase 2a Partly Randomised Study Evaluating Leronlimab in Patients With Presumed Non‐Cirrhotic Metabolic Dysfunction–Associated Steatohepatitis

open access: yesLiver International Communications, Volume 6, Issue 4, December 2025.
ABSTRACT Chemokine receptor type 5 (CCR5) is upregulated in the livers of patients with metabolic dysfunction–associated steatohepatitis (MASH). Leronlimab, a humanised IgG4κ monoclonal antibody, directly binds the extracellular domains of CCR5, modulates downstream signalling and potentially can slow, reverse or prevent fibrosis. The aim of this study
Melissa Palmer   +10 more
wiley   +1 more source

Vitamin‐Engineered Nanoplatforms in Precision Oncology: Integrating Immunotherapy, Delivery Systems, and Theranostics

open access: yesMedComm – Biomaterials and Applications, Volume 4, Issue 4, December 2025.
Vitamin‐derived nanoplatforms advance precision oncology by augmenting immunotherapy through dendritic cell activation, T‐cell reprogramming, and TME remodeling to enhance antitumor immunity, while enabling targeted therapeutic delivery. These systems integrate theranostic capabilities using vitamin‐conjugated imaging probes for concurrent tumor ...
Ruowa Xu   +3 more
wiley   +1 more source

Idiopathic Hypercalcemia of Infancy

open access: bronze, 1960
Tooru Nakao, Toshio Nitta, Takao Gotooda
openalex   +2 more sources

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear   +16 more
wiley   +1 more source

Genotype–Phenotype Correlations, Mortality, and Clinical Insights in Keratitis–Ichthyosis–Deafness Syndrome: A Comprehensive Review and Case Report

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero   +17 more
wiley   +1 more source

Detection of human T-cell leukemia virus antibodies in a Japanese T-cell leukemia patient with hypercalcemia [PDF]

open access: bronze, 1984
Y Nakao   +9 more
openalex   +1 more source

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