Results 31 to 40 of about 47,287 (251)

Teriparatide Induced Delayed Persistent Hypercalcemia [PDF]

, 2014
Teriparatide, a recombinant PTH, is an anabolic treatment for osteoporosis that increases bone density. Transient hypercalcemia is a reported side effect of teriparatide that is seen few hours following administration of teriparatide and resolves usually
Jaskirat Randhawa, Happy Sadiek, Nirosshan Thiruchelvam, Gaurav Kistangari   +3 more
core   +1 more source

A Case of Severe Hypercalcemia Causing Acute Kidney Injury: An Unusual Presentation of Acute Lymphoblastic Leukemia [PDF]

Childhood Kidney Diseases, 2017
Severe hypercalcemia is rarely encountered in children, even though serum calcium concentrations above 15-16 mg/dL could be life-threatening. We present a patient having severe hypercalcemia and azotemia.
Hye Sun Hyun, Peong Gang Park, Jae Choon Kim, Kyun Taek Hong, Hyoung Jin Kang, Kyung Duk Park, Hee Young Shin, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong   +9 more
doaj   +1 more source

Hypercalcemia during pregnancy: management and outcomes for mother and child [PDF]

, 2021
Diagnosing and treating hypercalcemia during pregnancy can be challenging due to both the physiological changes in calcium homeostasis and the underlying cause for the hypercalcemia.
Appelman-Dijkstra, N.M. (Natasha), Rjenmark, L. (Lars), Appelman-Dijkstra, N.M., Appelman-Dijkstra, Natasha M., Ertl, D.-A. (Diana- Alexandra), Zillikens, M.C., Zillikens, M.C. (Carola), Carola Zillikens, M., Winter, E.M. (Elizabeth M.), Rjenmark, Lars, Winter, E.M., Rjenmark, L., Ertl, Diana Alexandra, Ertl, D.A., Winter, Elizabeth M., Natasha M. Appelman-Dijkstra, M. C. Zillikens, Diana- Alexandra Ertl, Lars Rjenmark, Elizabeth M. Winter   +19 more
core   +1 more source

Hypercalcemia of Malignancy in Thymic Carcinoma: Evolving Mechanisms of Hypercalcemia and Targeted Therapies

Case Reports in Endocrinology, 2017
Here we describe, to our knowledge, the first case where an evolution of mechanisms responsible for hypercalcemia occurred in undifferentiated thymic carcinoma and discuss specific management strategies for hypercalcemia of malignancy (HCM).
Cheng Cheng, Jose Kuzhively, Sanford Baim   +2 more
doaj   +1 more source

Hyperkalzämie [Hypercalcemia]

, 2020
Calcium is pivotal for neuromuscular function, coagulation, and signal transduction. An imbalance of enteral calcium uptake, deposition in and resorption from bones, and renal calcium elimination causes hypercalcemia. The dissociation between total serum
Kettritz, R.
core   +1 more source

Familial hypocalciuric hypercalcemia case formulations.

, 2023
Familial hypocalciuric hypercalcemia case formulations.
Ralf Schmidmaier (444180), Sarah Frederike Brose (16052578), Leah T. Braun (9103978), Martin R. Fischer (9539552), Karin Binder (5018999), Martin Reincke (150169)   +5 more
core   +1 more source

Severe hypercalcemia caused by parathyroid hormone in a rectal cancer metastasis: a case report

BMC Endocrine Disorders, 2021
Background Hypercalcemia of malignancy is relatively common in several cancers. However, in colorectal cancer, paraneoplastic phenomena that cause hypercalcemia is uncommon.
Vegard Heimly Brun, Erik Knutsen, Helge Stenvold, Hanne Halvorsen   +3 more
doaj   +1 more source

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

Advanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao, Jinpei Sun, Chenxi Zhao, Yuting Cang, Keyu Zong, Yuxin Guo, Yajing Wang, Di Meng, Qingling Song, Lei Wang   +9 more
wiley   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Challenges in the management of hypercalcemia in pregnancy – Case report of two cases

Case Reports in Women's Health
Hypercalcemia in pregnancy is rare and can pose a great diagnostic challenge due to its asymptomatic presentation. It is associated with maternal complications such as urolithiasis, pancreatitis, renal insufficiency and preeclampsia, fetal complications ...
Shu Hui Lim, Weiying Lim, Serene Pei Ting Thain   +2 more
doaj   +1 more source