Results 61 to 70 of about 65,906 (319)

Gallium β‐Cyclodextrin Nanoparticles Containing both Gallium Protoporphyrin and Gallium Nitrate Exhibit Antimicrobial Activity against Nontuberculous Mycobacteria in Vitro and in Vivo

Advanced Therapeutics, EarlyView.
Cyclodextrin nanoparticle containing both Ga(NO3)3 and GaPP is synthesized and tested against non‐tuberculous mycobacteria (NTM). The in vivo efficacy of the nanoparticle therapy is additionally tested by treating pulmonary NTM infections in mice and observed much greater effectiveness in bacterial clearance and survival of mice.
Seoung‐ryoung Choi, Bradley E. Britigan, Prabagaran Narayanasamy   +2 more
wiley   +1 more source

Chronic adult T-cell Leukemia in a young male after blood transfusion as a newborn [PDF]

, 2016
Human T-cell Lymphotropic virus type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HTM/TSP).
Altube, Alejandra, Berini, Carolina Andrea, Biglione, Mirna Marcela, Cabral Lorenzo, María Cecilia, Colucci, Magalí, Cánepa, Camila, Deves, Alberto, Halperin, Nora Silvia, Hermine, Olivier, Rojas, Francisca, Ruggieri, Matias   +10 more
core   +2 more sources

Sono‐Controllable Janus Hydrogel Platform for Sequential Tumor Eradication and Bone Regeneration in Metastatic Breast Cancer

Advanced Science, EarlyView.
Sequential tumor eradication and bone regeneration remain a significant challenge for patients with breast cancer bone metastases. This study develops a novel Janus hydrogel platform, which can achieve tumor elimination and bone repair under the action of different ultrasound frequencies.
Yitong Li, Yunyun Liu, Chuyun Lou, Xuejun Chen, Ying Zhang, Hui Shi, Jiayi Qiu, Shen Zhang, Taixia Wang, Xiaowei Wang, Haohao Yin, Huixiong Xu, Yifeng Zhang   +12 more
wiley   +1 more source

Osborn Waves: History and Significance [PDF]

, 2004
The Osborn wave is a deflection with a dome or hump configuration occurring at the R-ST junction (J point) on the ECG (Fig. 1). In the historical view, different names have been used for this wave in the medical literature, such as “camel-hump sign ...
Atarashi, Hirotsugu, Hirayama, Yoshiyuki, Katoh, Takao, Kobayashi, Yoshinori, Kodani, Eitaroh, Maruyama, Mitsunori, Takano, Teruo   +6 more
core   +2 more sources

Investigation into the Pancreatic Pathogenesis of SFTSV across Multiple Levels

Advanced Science, EarlyView.
A retrospective analysis revealed that 17.6% of severe fever with thrombocytopenia syndrome (SFTS) patients met the diagnostic criteria for clinically confirmed pancreatitis. Using human pancreatic organoids and murine models demonstrated that SFTSV exhibits a specific pancreatic tropism, leading to cell death and initiating a strong inflammatory ...
Xiaohan Liu, Zhihao Xu, Yilun Tong, Changtai Wang, Yueqi Yao, Yujie Diao, Jingyuan Ma, Shijun Zhou, Yinan Du, Zhenhua Zhang, Gang Xu   +10 more
wiley   +1 more source

Multiple Myeloma Presenting as Hypercalcemia-Induced Acute Severe Pancreatitis: A Case Report

Gastro Hep Advances
Hypercalcemia is a known presentation of multiple myeloma along with anemia, renal failure, and bone pains (CRAB: hypercalcemia, renal failure, anemia, and bone lesions).
Anjuman Fayaz, Altaf Hussain Shah, Mushtaq Ahmad Khan, Shaheena Parveen   +3 more
doaj   +1 more source

Clinlabomics‐Enabled Blending Ensemble Learning for Low‐Cost Pan‐Cancer Detection and Classification Using Routine Clinical Laboratory Data

Advanced Intelligent Systems, EarlyView.
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang, Lin Li, Long Cheng, Yujie Liu, Zhaoqing Liu, Jiangpeng Wu, Pengyi Zhang, Jiarui Wang, Dekui Zhang, Shuyan Li   +9 more
wiley   +1 more source

Double Trouble: A Case of Primary Hyperparathyroidism and Humoral Hypercalcemia of Malignancy Secondary to Epithelioid Angiosarcoma Occurring in a Single Patient

AACE Clinical Case Reports, 2016
: Objective: Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia and is the third most common endocrine disorder. Hypercalcemia occurs in an estimated 10 to 30% of patients with cancer, with humoral hypercalcemia of malignancy ...
Thomas J. Jensen, MD, Cecilia C. Low Wang, MD   +1 more
doaj   +1 more source

Electrolyte Abnormalities on ECG [PDF]

, 2011
The authors review the characteristic changes that hypercalcemia, hyperkalemia, hypokalemia, and other serum electrolyte abnormalities can cause on an ...
Ginter, James F., Loftis, Patrick
core   +1 more source

De Novo Heterozygous ZFX Frameshift Variant in a Female With an X‐Linked Neurodevelopmental Disorder

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Germline ZFX variants are associated with an X‐linked neurodevelopmental disorder, with 14 males and 16 females reported to date. We describe a 20‐year‐old female with a heterozygous ZFX frameshift variant, p.(Met666Valfs*2), identified by genome sequencing, previously reported in an affected male.
Iftekhar A. Showpnil, Allison Daley, Emily R. Sites, Shayne M. Plourde, Jesse M. Hunter, Dennis W. Bartholomew, April N. Lehman, Daniel C. Koboldt, Rolf W. Stottmann   +8 more
wiley   +1 more source