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Tendon Pathology in Hypercholesterolemia and Familial Hypercholesterolemia

Current Rheumatology Reports, 2017
Hypercholesterolemia (HC), or high cholesterol, is usually caused by diet, other health conditions, or inherited diseases, such as familial hypercholesterolemia (FHC). Studies have shown patients with hypercholesterolemia are more prone to tendon injury and impaired healing.
Brittany, Taylor   +2 more
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Psyllium in Hypercholesterolemia

Annals of Pharmacotherapy, 1995
In summary, within a controlled study situation, psyllium seems to be effective in lowering total and LDL cholesterol by 4-8% and 6-13%, respectively. Compared with conventional antilipidemic agents such as lovastatin, which lowers total cholesterol 30%, LDL cholesterol 40%, and triglycerides 20%, the effect of psyllium on lipids is minimal, and its ...
E K, Chan, D J, Schroeder
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Screening for Hypercholesterolemia

Annual Review of Medicine, 1990
The detection of individuals with hypercholesterolemia has received world-wide support as a means of determining who would benefit from dietary and pharmacologic interventions. However, the clinician or public health practitioner should be aware of several issues that must be resolved before cholesterol screening can attain maximal impact.
T A, Pearson, S, Bowlin, W R, Sigmund
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Lovastatin for Hypercholesterolemia

Drug Intelligence & Clinical Pharmacy, 1988
Lovastatin is the first 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor approved for the treatment of primary hypercholesterolemia. It is indicated as adjunctive therapy to dietary control and should be initiated at 20 mg/d in the evening. With higher dosages, twice-daily dosing is preferred, particularly when the dosage reaches the
F P, Zeller, K C, Uvodich
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Guggul for hypercholesterolemia

American Journal of Health-System Pharmacy, 2005
The mukul myrrh tree ( Commiphora mukul ), a native of India, secretes the substance guggul (also known as guggulu or guggulipid) when its bark is injured. Guggul has been used in Ayurvedic medicine for thousands of years to treat arthritis and obesity.
Kelly M, Shields, Michael P, Moranville
openaire   +2 more sources

Hypercholesterolemia and angiogenesis

The American Journal of Cardiology, 1993
Hypercholesterolemia is associated with endothelial cell dysfunction, which may be partly related to an accumulation of toxic lipoprotein degradation products in artery walls. Oxidized low-density lipoprotein and its products have been incriminated in the impairment of transmembrane signaling, a process that may alter the responsiveness of endothelial ...
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Hypercholesterolemia and dyslipidemia

Current Treatment Options in Cardiovascular Medicine, 2000
Disorders of cholesterol and lipoprotein metabolism are at the heart of atherosclerosis and coronary artery disease (CAD). CAD, however, is a metabolic disorder that involves a complex interaction between genetic susceptibility and environmental conditions.
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Hypercholesterolemia of Cholestasis

Cardiology in Review
Cholesterol is a lipid of widespread physiologic and pathologic importance, whose homeostasis is tightly regulated through multiple mechanisms, including transport via low-density lipoprotein. Elevated serum low-density lipoprotein strongly correlates with the development of atherosclerotic cardiovascular disease.
Maxwell, Charlat   +5 more
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Therapy for Hypercholesterolemia

Primary Care: Clinics in Office Practice, 1990
For most patients, hypercholesterolemia can be effectively lowered with drug therapy but only after several issues have been considered. First, drug therapy should never be considered without adequate dietary intervention. Dietary therapy may be effective for many patients with mild to moderate elevations in cholesterol. None of the drugs used to treat
B L, Carter, F R, Bakht
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Treatment of Hypercholesterolemia

Medical Clinics of North America, 1982
After discussing the indications for treatment of familial hypercholesterolemia and the importance of a differential diagnosis, the authors describe drug therapy for the disorder with special attention to combined drug regimens. The surgical treatment of hypercholesterolemia and the treatment of homozygous and other forms of hypercholesterolemia are ...
J P, Kane, M J, Malloy
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