Results 91 to 100 of about 2,437,081 (240)

Multiple Cerebral Infarcts and Encephalopathy as the First Clinical Manifestations of Hypereosinophilic Syndrome: A Case Report and Narrative Review

open access: yesPulse
Background: Hypereosinophilic syndrome is characterized by a peripheral blood eosinophil count >1.5 × 103/μL on two different examinations within a month of each other and/or a 20% or higher percentage of eosinophils in a bone marrow section ...
Sonia Romano   +6 more
doaj   +1 more source

Pleural mesothelioma and venous thrombosis: the eosinophilia link [PDF]

open access: yes, 2008
Peripheral blood eosinophilia and vascular occlusions are rare occurrences in patients with pleural mesothelioma whereas eosinophilia may associate with thrombosis.
Paul Ames, Win Aye
core   +1 more source

Hypereosinophilia Associated With Antisynthetase Syndrome With Anti‐Ro52/PL12 Co‐Positivity: An Unusual Presentation

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Hypereosinophilia is uncommon in ASS and this presentation makes diagnosis more challenging. Anti‐PL12's role in the severity of ILD is controversial but its association with anti‐Ro52 seems to give a more serious disease phenotype. African ethnicity could be a negative prognostic factor, associated with lung disease severity.
Abeline Kapuczinski   +4 more
wiley   +1 more source

Hypereosinophilic syndromes

open access: yesItalian Journal of Medicine, 2013
Background: The last few years have seen a complete change in the etiopathogenetic features, classification and therapeutic approach of the hypereosinophilic syndrome (HES), a multiorgan targeted blood disease. The discovery of a genetic mutation and the occurrence of a new fusion gene, named FIP1L1-PDGFRA (FIP gene), in some patients allowed the ...
Giuseppe Civardi   +4 more
openaire   +5 more sources

Validation of the Primerdesign Quantitative Allele Specific Amplification Kit for the Detection of JAK2V617F Mutation

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 6, March 2026.
The PrimerDesign Quasa kit demonstrates efficacy as a reliable assay for the detection of JAK2V617F mutation, exhibiting potential for quantitative analysis when samples are analysed in duplicate. This assay validation information may prove valuable to laboratories seeking to implement a simplified JAK2V617F mutational test. ABSTRACT Introduction Janus
Deborah Vaz   +2 more
wiley   +1 more source

Clinical and Pathological Features of Vasculitic Neuropathy: A Single‐Center Study in China

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
Vasculitic neuropathy in mainland China predominantly presents as axonal sensorimotor neuropathy. Systemic VN shows more frequent transmural inflammatory infiltration, whereas EGPA is more common in cases without infiltration. Most treated patients achieved remission, and the overall prognosis was relatively favorable, underscoring the importance of ...
Xiaoyu Zhou   +9 more
wiley   +1 more source

Staphylococcus aureus Endocarditis as a Complication of Toxocariasis-Associated Endomyocarditis With Fibrosis: A Case Report [PDF]

open access: yes, 2016
Complications associated with Toxocara canis infection are rare. We present a case of a patient with Staphylococcus aureus endocarditis as a complication of an endomyocardial fibrosis caused by T canis.
Balestra, Gianmarco   +5 more
core   +1 more source

Development of Pediatric Dosing for Mepolizumab in Severe Asthma Based on Extrapolation of Data From Adult Patients and a Phase II Open‐Label Pediatric Trial

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.
Abstract The benefit–risk profile of mepolizumab in severe asthma was established through clinical trials in adults, leading to EU and US approvals in 2015. To support a pediatric indication (≥6 years), an extrapolation approach was implemented. This extrapolation and its validation were informed by data from Phase III trials in adults (N = 1841) and ...
Atul Gupta   +8 more
wiley   +1 more source

Eosinophilic Myocarditis: An Often-Overlooked Diagnosis in Patients Presenting with Heart Failure

open access: yesCase Reports in Cardiology, 2022
Introduction. Hypereosinophilic syndrome (HES) is a rare disease characterized by unexplained peripheral eosinophilia along with evidence of end-organ damage.
Young Min Cho   +4 more
doaj   +1 more source

Chronic intestinal pseudo-obstruction in a Bernese Mountain Dog [PDF]

open access: yes, 2009
Chronic Intestinal Pseudo-Obstruction (CIPO) is a rare syndrome characterized by chronic intestinal dilation and dysmotility in the absence of mechanical obstruction.
Chiers, Koen   +5 more
core  

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