Results 61 to 70 of about 18,414 (250)

Evaluation of Pediatric and Young Adult Cancer Survivors at Risk of Long‐Term Kidney Complications

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nephrotoxic chemotherapy, nephrectomy, abdominal radiotherapy exposure, and the presence of kidney or pelvic tumors are risk factors associated with long‐term kidney complications. This study aimed to determine the prevalence of long‐term kidney complications in patients who survived pediatric and young adult cancer and were exposed
Ahmed Zeid, Sara Delap, Claudia Mosquera Vasquez, Randal S. Olshefski, Joseph R. Stanek, Lory Guthrie, Diana Zepeda‐Orozco   +6 more
wiley   +1 more source

Renal functional reserve and tubular function in patents with type 2 diabetes mellitus

Сахарный диабет, 2011
Aim. To study renal functional reserve and partial functions in patents with type 2 diabetes mellitus in the absence of renal lesionsMaterials and methods.
Dilyara Makhmutrievna Khakimova, Adelya Nailevna Maksudova, Il'dar Gazimdzhanovich Salikhov   +2 more
doaj   +1 more source

Tracing the molecular landscape of diabetic nephropathy: Insights from machine learning and experiment verification

Journal of Diabetes Investigation, EarlyView.
Diabetic nephropathy (DN) is a major complication of diabetes, leading to end‐stage renal disease. This study identified 109 differentially expressed genes (DEGs) and validated LOX as a novel diagnostic biomarker through integrated bioinformatics and experimental analysis.
Shahad W. Kattan, Ahmed M. Basri, Mohammad H. Alhashmi, Amany I. Almars, Reem Hasaballah Alhasani, Ifat Alsharif, Ikhlas A. Sindi, Ahmad H. Mufti, Iman S. Abumansour, Nasser A. Elhawary, Aishah Abdullah Qahtani, Hailah M. Almohaimeed   +11 more
wiley   +1 more source

Induction of proximal tubular proliferation and lengthening in response to sodium glucose linked cotransporter‐2 inhibition in experimental rats

Journal of Diabetes Investigation, EarlyView.
While SGLT2 accounts for >90% of kidney glucose reabsorption, its pharmacological inhibition or genetic knockdown reduces glucose reabsorption by only 50%. We found that the SGLT2 inhibitor, dapagliflozin, induced an early, transient hyperplastic response in the SGLT1‐expressing S3 segment of the proximal tubule followed by an increase in its length ...
Ellen Wu, Sarah Macklin, Yanling Zhang, Kerri Thai, Linda Nghiem, Caterina Di Ciano‐Oliveira, Nuno Coelho, Hai Wang, Suzanne L. Advani, Jean‐François Desjardins, Darren A Yuen, Paraish Misra, Kim A. Connelly, Jens R. Nyengaard, Richard E. Gilbert   +14 more
wiley   +1 more source

Stabilization of porous glass reverse-osmosis membranes [PDF]

, 1972
Application of porous glass in form of capillary tubes for low capacity ion exchange in hyperfiltration experiments is discussed. Efficiency of desalination by process of reverse osmosis is described. Stabilization of porous glass membrane by presence of
Ballou, E. V., Leban, M. I., Wydeven, T.
core   +1 more source

Cardiorespiratory fitness and sports activities in children and adolescents with solitary functioning kidney [PDF]

, 2016
Background: An increasing number of children with chronic disease require a complete medical examination to be able to practice physical activity. Particularly children with solitary functioning kidney (SFK) need an accurate functional evaluation to ...
DE CASTRO, Giovanna, DUSE, MARZIA, Falsaperla, R, FAVORITI, ALESSANDRA, LAMBIASE, CATERINA, LUBRANO, Riccardo, Paoli, S, Ricupito, F, TANCREDI, Giancarlo, Vitaliti, G, ZICARI, Anna Maria   +10 more
core   +2 more sources

Association between Depression and Renal Hyperfiltration in a General Chinese Population

Kidney & Blood Pressure Research, 2019
Background: Depression is prevalent in patients with all stages of CKD and is associated with adverse outcome. Abnormally elevated GFR, or hyperfiltration, may play a crucial role in the initiation and progression of CKD. However, the association between
Miao Lin, Huibin Huang, Jin Yao, Jixing Liang, Liantao Li, Wei Lin, Lixiang Lin, Fuyuan Hong, Jieli Lu, Yufang Bi, Weiqing Wang, Junping Wen, Gang Chen   +12 more
doaj   +1 more source

Impact of body mass index on the association between kidney function and insulin resistance in diabetic and nondiabetic populations

Journal of Diabetes Investigation, EarlyView.
In diabetes with overweight/obesity, eGFR was negatively linearly associated with HOMA‐IR, and creatinine was positively linearly associated with HOMA‐IR. In non‐diabetes with overweight/obesity, the relationship between eGFR and HOMA‐IR was L‐shaped, and the relationship between uric acid and HOMA‐IR was inverted L‐shaped.
Ruo Zhang, Malgorzata A Garstka, Chunhong Zhang, Shimei Ding, Jing Xu   +4 more
wiley   +1 more source

The association between skinfold thicknesses and estimated glomerular filtration rate in adolescents: a cross-sectional study

BMC Nephrology, 2022
Background Obesity is one of the causes of glomerular hyperfiltration. Studies on the relationship between body fat content and glomerular hyperfiltration have been limited to special children.
Yongchang Yang, Yubin Wu
doaj   +1 more source

Creatinine-Based Formulae Poorly Match in the Classification of Hypofiltration or Hyperfiltration in a General Population of Adolescents: A Retrospective Analysis of a Cross-Sectional Study

Frontiers in Pediatrics, 2021
Pediatric formulae to estimate glomerular filtration rate (eGFR) give a broad range of values. Their consistency in assigning the subjects as hypofiltrating or hyperfiltrating is unknown.
Katarína Šebeková, Radana Gurecká, Radana Gurecká, Ĺubomíra Tóthová, Ĺudmila Podracká, Ĺudmila Podracká   +5 more
doaj   +1 more source