Results 71 to 80 of about 20,309 (259)

Renal hyperfiltration revisited—Role of the individual body surface area on mortality [PDF]

open access: hybrid, 2023
Päivi Korhonen   +3 more
openalex   +1 more source

Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone   +6 more
wiley   +1 more source

Concerted EP2 and EP4 Receptor Signaling Stimulates Autocrine Prostaglandin E2 Activation in Human Podocytes

open access: yesCells, 2020
Glomerular hyperfiltration is an important mechanism in the development of albuminuria. During hyperfiltration, podocytes are exposed to increased fluid flow shear stress (FFSS) in Bowman’s space.
Eva Mangelsen   +6 more
doaj   +1 more source

Nierenfunktion und nephronsparende Operationstechnik: Nephrologische Sicht [PDF]

open access: yes, 2008
Das Nierenzellkarzinom ist ein häufiger Tumor, welcher mit zunehmendem Alter vor allem bei Männern auftritt. Eine steigende Inzidenz wird in den letzten Jahren festgestellt, vor allem wegen der Zunahme von radiologischen Untersuchungen, im Rahmen ...
Wüthrich, R P
core   +2 more sources

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

The effect of a multidisciplinary weight loss program on renal circadian rhythm in obese adolescents

open access: yes, 2019
Adolescent obesity is a serious health problem associated with many comorbidities. Obesity-related alterations in circadian rhythm have been described for nocturnal blood pressure and for metabolic functions.
Bruneel, Elke   +8 more
core   +1 more source

A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. [PDF]

open access: yes, 2019
The intra-renal dopamine (DA) system is highly expressed in the proximal tubule and contributes to Na+ and blood pressure homeostasis, as well as to the development of nephropathy.
Baker, Dewleen G   +15 more
core   +2 more sources

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

open access: yesExperimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal   +9 more
wiley   +1 more source

Trace ions rejection tunning in NF by selecting solution composition: Ion permeances estimation [PDF]

open access: yes, 2017
Nanofiltration (NF) is suggested to selectively remove ionic species in aqueous process streams taking benefit of both membrane and aqueous solution composition. The importance of predicting and optimizing selective ion rejections by NF not only of major
Cortina Pallás, José Luís   +3 more
core   +2 more sources

Stabilization of porous glass reverse-osmosis membranes [PDF]

open access: yes, 1972
Application of porous glass in form of capillary tubes for low capacity ion exchange in hyperfiltration experiments is discussed. Efficiency of desalination by process of reverse osmosis is described. Stabilization of porous glass membrane by presence of
Ballou, E. V., Leban, M. I., Wydeven, T.
core   +1 more source

Home - About - Disclaimer - Privacy