Results 141 to 150 of about 74,881 (294)

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Cellular microenvironment of erythropoietin‐producing cells in hypoxic and injured mouse kidneys

Experimental Physiology, EarlyView.
Abstract The main sources of circulating erythropoietin (Epo) in the adult are kidney Norn cells, a recently identified interstitial cell type capable of becoming renal Epo‐producing (REP) cells following a local decrease in tissue oxygenation. REP cells are restricted to small clusters in the corticomedullary border region, suggesting that their ...
Olga M. Lempke, Thomas Knöpfel, Stellor Nlandu Khodo, Roland H. Wenger   +3 more
wiley   +1 more source

A conditional Bayesian approach for testing independence in two-way contingency tables

Kuwait Journal of Science, 2013
Bayesian methods for exact small-sample analysis with categorical data in   contingency tables are considered. Point null hypotheses versus two-sided hypothesis are tested concerning log odds ratios in these tables with fixed row margins. The conditional
Z. SABERI, M. GANJALI
doaj  

Overlapping Probabilities of Top Ranking Gene Lists, Hypergeometric Distribution, and Stringency of Gene Selection Criterion [PDF]

, 2006
Wen Fury, Franak Batliwalla, Peter K. Gregersen, Wentian Li   +3 more
openalex   +1 more source

C‐X‐C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8+ T cells within the tumor microenvironment

International Journal of Cancer, Volume 158, Issue 6, Page 1740-1754, 15 March 2026.
What's new? In addition to governing daily variations in biological activity, the circadian clock regulates immune cell migration into tumors. Whether this influence extends to immune cell localization within the tumor microenvironment (TME) is unknown. Here, using cell and animal models, the authors investigated immune cell distribution within the TME
Akito Tsuruta, Marina Fujimoto, Yasuha Hiraoka, Aoi Taniguchi, Yuki Shiiba, Takuto Inoki, Tomoaki Yamauchi, Yuya Yoshida, Naoya Matsunaga, Shigehiro Ohdo, Satoru Koyanagi   +10 more
wiley   +1 more source

A comprehensive review of cluster methods for drug–drug interaction network

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The detection of drug–drug interaction (DDI) is crucial to the rational use of drug combinations. Experimentally, DDI detection is time‐consuming and laborious. Currently, researchers have developed a variety of computational methods to predict DDI.
Shuyuan Cao, Guixia Liu, Xiangrun Zhou, Ji Lv   +3 more
wiley   +1 more source

Toward Psychometric Learning Analytics: Augmenting the Urnings Algorithm with Response Times

Journal of Educational Measurement, Volume 63, Issue 1, Spring 2026.
Abstract Adaptive learning systems (ALS) aim to tailor the educational material to match the student's needs, ultimately improving the learning outcomes. An ALS dynamically adjust the level of practice based on the student's ability; therefore, obtaining accurate ability estimates is crucial.
Bence Gergely, Maria Bolsinova
wiley   +1 more source

ncFN: a comprehensive non-coding RNA function annotation framework based on a global and heterogeneous biomolecular network. [PDF]

Noncoding RNA Res
Long M, Liu H, Yuan M, Zhou X, Zhang T, Wang Q, Jiang W.   +6 more
europepmc   +1 more source

High‐throughput single‐cell DNA methylation and chromatin accessibility co‐profiling with SpliCOOL‐seq

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
SpliCOOL‐seq achieves high‐throughput single‐cell co‐profiling of DNA methylation and chromatin accessibility. DNMT inhibitors caused cancer cell demethylation with divergent patterns. SpliCOOL‐seq enables the discovery of genes related to LUAD tumorigenesis. Ageing and LUAD tumorigenesis may share similar epigenetic alterations.
Qingmei Shen, Enze Deng, Ling Luo, Jingna Zhang, Qifeng Yang, Dan Su, Xiaoying Fan   +6 more
wiley   +1 more source

Drug discovery for chemotherapeutic resistance based on pathway-responsive gene sets and its application in breast cancer. [PDF]

Front Bioinform
Feng D, Hao J, Li L, Chen J, Liu X, Zhang R, Han H, Li T, Wang X, Li X, Yu L, Li B, Li J, Wang L.   +13 more
europepmc   +1 more source