Results 161 to 170 of about 94,918 (265)

Research article proteomics-based plasma biomarkers for predicting CRKP infection in ICU sepsis patients. [PDF]

Front Pharmacol
Mao Z, Yao K, Wang L, Wang Y, Yuan Y.
europepmc   +1 more source

Transcriptomic analysis reveals the hepatic response mechanisms of the Chinese spiny frog (Quasipaa spinosa) to Citrobacter freundii infection

Journal of the World Aquaculture Society, Volume 57, Issue 3, June 2026.
Abstract To elucidate the pathogen and host response mechanisms underlying mass mortality in Quasipaa spinosa, dominant bacteria were isolated from diseased individuals and identified as Citrobacter freundii by morphological, physiological, and biochemical characterization, 16S rRNA sequencing, and phylogenetic analysis.
Yanhong Li, Baohong Zhou, Yiran Lu, Yi Zang, Minghao Hu, Qiaochen Jin, Wenbin Fang, Shanjian Zheng   +7 more
wiley   +1 more source

ncFN: a comprehensive non-coding RNA function annotation framework based on a global and heterogeneous biomolecular network. [PDF]

Noncoding RNA Res
Long M, Liu H, Yuan M, Zhou X, Zhang T, Wang Q, Jiang W.   +6 more
europepmc   +1 more source

Benzoxazinoid‐mediated microbiome feedbacks enhance Arabidopsis growth and defence

New Phytologist, Volume 250, Issue 5, Page 3334-3348, June 2026.
Summary Plants modulate their surrounding microbiome via root exudates and such conditioned soil microbiomes feed back on the performance of the next generation of plants. How plants perceive altered soil microbiomes and modulate their performance in response to such microbiome feedbacks, however, remains largely unknown.
Katja Stengele, Lea Stauber, Lisa Thoenen, Henry Janse van Rensburg, Viola D'Adda, Klaus Schlaeppi   +5 more
wiley   +1 more source

Single-cell spatiotemporal transcriptomic and chromatin accessibility profiling in developing postnatal human and macaque prefrontal cortex. [PDF]

Nat Neurosci
Zhang J, Li M, Wang M, Sun Y, Yin C, Yang S, Wang B, Liu Z, Wang W, Liu M, Zhao Y, Zhou X, Cai L, Zhong S, Wang X, Wu Q.   +15 more
europepmc   +1 more source

Phosphate starvation induces root cell‐type‐specific transcriptional responses and alternative splicing

New Phytologist, Volume 250, Issue 5, Page 3212-3229, June 2026.
Summary Phosphate (Pi) is an essential nutrient for plant growth, and understanding how Arabidopsis thaliana root cells respond to Pi deficiency is crucial to decipher whole plant responses. We perform high‐resolution transcriptomic profiling across five distinct root cell types, identifying differentially expressed genes (DEGs) and differential ...
Mary‐Paz González‐García, Mónica Lanza, Victoria Baca‐González, Estefano Bustillo‐Avendaño, Laura Serrano‐Ron, Sara González‐Bodi, Jose M. García‐Mina, Ángel M. Zamarreño, María Garnica, Miguel A. Moreno‐Risueno, Elena Caro, Juan C. del Pozo   +11 more
wiley   +1 more source

High-content CRISPR activation screens identify synthetically lethal RNA-based mechanisms to sensitize cancer cells to targeted T cell cytotoxicity. [PDF]

Nat Genet
Akana RV, Yoe J, Laveroni O, Sun C, Kim YM, Jerby L.   +5 more
europepmc   +1 more source

The abundance of pollen coat small signaling proteins shows limited convergence between independent selfing transitions in Arabidopsis and Capsella

New Phytologist, Volume 250, Issue 5, Page 3460-3474, June 2026.
Summary In plants, a key example of convergence is the repeated evolution of floral traits associated with the transition from outcrossing to self‐fertilization, often resulting in the ‘selfing syndrome’ (e.g. reduced flower size and loss of scent). However, potentially overlooked changes concern the pollen coat, which plays a role in different aspects
Ömer İltaş, Luciana Salomon, Martin Kovačik, Martin Čertner, Pavel Talacko, Karel Harant, Said Hafidh, Clément Lafon Placette   +7 more
wiley   +1 more source

Multi-dimensional immunoprotection of Ganoderma lucidum spore oil in immunosuppressed mice via microbiome-proteome-metabolome network analysis. [PDF]

Sci Rep
Deng S, Wu X, Xu W, Wu X, Cai H, Wang S, Liu J, Cao J.   +7 more
europepmc   +1 more source

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source