Results 141 to 150 of about 34,479 (237)
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang +6 more
wiley +1 more source
Rab8a‐dependent tethering of lipid droplets to mitochondria sustains fatty acid oxidation and cardiomyocyte metabolic flexibility under normoxia. During hypoxia/reoxygenation, Rab8a loss and PLIN5‐associated lipophagy uncouple lipid breakdown from mitochondrial utilization, driving lipotoxicity and cell death.
Jialing Tang +6 more
wiley +1 more source
This study provides comprehensive insights into the epigenetic impacts of dietary interventions, specifically contrasting the effects of a vegan diet (VD) with a meat‐rich diet (MR) on DNAm profiles and their potential health implications. Dietary habits can significantly reshape the epigenomic landscape within 1 month, with the VD exerting a more ...
L. Karbacher +6 more
wiley +1 more source
Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren +7 more
wiley +1 more source
Caspase‐mediated cleavage events hidden by secondary proteolysis during apoptosis
Abstract Caspases are cysteine proteases that cleave specific proteins to control a range of cellular processes including cell death, inflammation, and differentiation. Proteomic approaches, like N‐terminomics, have been central to identifying both cleaved proteins and where they are cleaved.
Fatemeh Fotouhi +4 more
wiley +1 more source
Modeling small-angle scattering data of porous and/or bicontinuous structures in <i>n</i> dimensions. [PDF]
Frielinghaus H.
europepmc +1 more source
A small‐angle scattering model for broad correlation peaks and small diffuse scattering
For porous and/or bicontinous structures with rather broad correlation peaks and small diffuse scattering, a heuristic theory makes the connection to conditions of material production.Porous and/or bicontinuous structures often display a pronounced correlation peak in their small‐angle scattering that indicates a preferred domain spacing d.
Henrich Frielinghaus
wiley +1 more source
The Exact Hypergeometric Posterior Method for Accurate Inference of Population Size from Mark-Recapture Data. [PDF]
Mirzaee D, Malekpour SA, Kalirad A.
europepmc +1 more source
ABSTRACT Peripheral artery disease (PAD) is a progressive atherothrombotic disorder affecting more than 230 million people worldwide. Conventional animal models of chronic hindlimb ischemia (HLI) are highly invasive, technically challenging, fail to account for anatomical variation, and may not accurately recapitulate progressive PAD pathophysiology ...
Oliver Kitzerow +4 more
wiley +1 more source
Que/n-HA/PGCL microspheres orchestrate bone repair via context-dependent osteoimmune mechanisms: a transcriptomic dissection of direct and immune-mediated signaling. [PDF]
Han C +6 more
europepmc +1 more source

