Results 171 to 180 of about 549,355 (294)

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

open access: yesAging Cell, EarlyView.
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar   +18 more
wiley   +1 more source

Convergence of Magnus integral addition theorems for confluent hypergeometric functions. [PDF]

open access: yesIntegral Transform Spec Funct, 2016
Cohl HS, Hirtenstein JE, Volkmer H.
europepmc   +1 more source

The Explicit Hypergeometric-Modularity Method I [PDF]

open access: yesarXiv
The theories of hypergeometric functions and modular forms are highly intertwined. For example, particular values of truncated hypergeometric functions and hypergeometric character sums are often congruent or equal to Fourier coefficients of modular forms.
arxiv  

The Lipidomic Profile Discriminates Between MASLD and MetALD

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 8, Page 1357-1371, April 2025.
HDL‐centric lipidomic biomarkers, particularly within large and medium HDL subfractions, distinguish metabolic dysfunction and alcohol‐related liver disease from metabolic dysfunction‐associated steatotic liver disease, suggesting potential biomarkers for clinical differentiation.
Kai Markus Schneider   +15 more
wiley   +1 more source

Altered immune response is associated with sex difference in vulnerability to Alzheimer's disease in human prefrontal cortex

open access: yesBrain Pathology, Volume 35, Issue 3, May 2025.
This study analyzes four public transcriptome datasets from AD patients and age‐matched controls, revealing that the transcriptomic profile in female controls closely resembles that of AD patients. We identified a co‐expressed gene module associated with AD, sex, and aging, enriched with immune‐related functions.
Huiying Wen   +14 more
wiley   +1 more source

OCT‐2 Is Associated With Pro‐Metastatic Epigenomic Properties of Triple‐Negative Breast Cancer Cells

open access: yesCancer Science, EarlyView.
The transcription factor OCT‐2 (encoded by POU2F2) is involved in the formation of super‐enhancers (SEs) in triple‐negative breast cancer (TNBC) cells. Overexpression of POU2F2 enhances the metastasis of TNBC cells in mice, and their expression is highly correlated to the poor prognosis of TNBC patients. ABSTRACT Triple‐negative breast cancer (TNBC) is
Kazuki Ogikubo   +7 more
wiley   +1 more source

A Case‐Driven Multi‐Omics Analysis for Longitudinal Ibrutinib Response Evaluation of Patients With Chronic Lymphocytic Leukemia

open access: yesEuropean Journal of Haematology, Volume 114, Issue 6, Page 973-981, June 2025.
ABSTRACT Patients with chronic lymphocytic leukemia (CLL) undergoing ibrutinib treatment often experience incomplete response, yet the molecular level underlying clonal inertia remains to be explored. We investigated the molecular and clinical dynamics of CLL during 16 months of ibrutinib monotherapy by analyzing blood samples from two patients who ...
Sólja Remisdóttir Veyhe   +9 more
wiley   +1 more source

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