Results 61 to 70 of about 549,355 (294)

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

Advanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou, Junliang Jiang, Yunqin Li, Xinyi Ding, Qiuping Tong, Ying Shi, Lei Xiao, Ling Chen   +7 more
wiley   +1 more source

Kampé de Fériet hypergeometric functions over finite fields [PDF]

arXiv, 2022
Kamp\'e de F\'eriet hypergeometric functions are two-variable hypergeometric functions, which are a generalization of Appell's functions. It is known that they satisfy many reduction and summation formulas. In this paper, we define Kamp\'e de F\'eriet hypergeometric functions over finite fields and show analogous formulas.
arxiv  

A relativistic hypergeometric function [PDF]

Journal of Computational and Applied Mathematics, 2005
AbstractWe survey our work on a function generalizing 2F1. This function is a joint eigenfunction of four Askey–Wilson-type hyperbolic difference operators, reducing to the Askey–Wilson polynomials for certain discrete values of the variables. It is defined by a contour integral generalizing the Barnes representation of 2F1.
openaire   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

A study on Horn matrix functions and its confluent cases [PDF]

arXiv, 2022
In this paper, we give the matrix version of Horn's hypergeometric function and its confluent cases. We also discuss the regions of convergence, the system of matrix differential equations of bilateral type, differential formulae and infinite summation formulae satisfied by these hypergeometric matrix functions.
arxiv  

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

Advanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li, Justin Torok, Shujing Zhang, Jessica Ding, Ning Wang, Courtney Lau, Shruti Kulkarni, Chaitali Anand, Julie Tran, Michael Cheng, Claire Lo, Binbin Lu, Yanzi Sun, Robert Damoiseaux, Xia Yang, Ashish Raj, Chao Peng   +16 more
wiley   +1 more source

A study on unification of generalized hypergeometric function and Mittag-Leffler function with certain integral transforms of generalized basic hypergeometric function

Researches in Mathematics
This research article explores some new properties of generalized hypergeometric function and its q-analogue. The connections between ${}_{2}{{R}_{1}}^{\upsilon }(\mathfrak{z})$, the Wright function, and generalized Mittag-Leffler functions are explored.
K.K. Chaudhary, S.B. Rao
doaj   +1 more source

On Some Formulas for the k-Analogue of Appell Functions and Generating Relations via k-Fractional Derivative

Fractal and Fractional, 2020
Our present investigation is mainly based on the k-hypergeometric functions which are constructed by making use of the Pochhammer k-symbol in Diaz et al. 2007, which are one of the vital generalizations of hypergeometric functions.
Övgü Gürel Yılmaz, Rabia Aktaş, Fatma Taşdelen   +2 more
doaj   +1 more source

Mixed-Type Hypergeometric Bernoulli–Gegenbauer Polynomials

Mathematics, 2023
In this paper, we consider a novel family of the mixed-type hypergeometric Bernoulli–Gegenbauer polynomials. This family represents a fascinating fusion between two distinct categories of special functions: hypergeometric Bernoulli polynomials and ...
Dionisio Peralta, Yamilet Quintana, Shahid Ahmad Wani   +2 more
doaj   +1 more source

Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity

Advanced Science, EarlyView.
Using a preclinical pancreatic cancer model, we identified that tumor progression restructures splenic immunity via myeloid cell expansion. MDCa@RBC‐Alipo nanobiologics were engineered to epigenetically and metabolically reprogram splenic myeloid cells, alleviating post‐ablation immunosuppression.
Shengbo Wu, Weichen Xu, Xuexia Shan, Liping Sun, Shuo Liu, Xixi Sun, Shaoyue Li, Xiaodong Hou, Xiaowan Bo, Chengzhong Peng, Bin Huang, Huixiong Xu, Wenwen Yue   +12 more
wiley   +1 more source