Results 91 to 100 of about 38,611 (276)
Advanced Science, EarlyView.Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang +10 more
wiley +1 more source
Proving hypergeometric identities by numerical verifications
Journal of Symbolic Computation, 2008 Proper and \(q\)-proper hypergeometric identities can be certified by checking a finite number \(n\) of initial values. The authors give a new method to estimate \(n\). The given examples show that the new estimates are smaller than the previous results.
Guo, Qiang-Hui +2 more
openaire +1 more source
Advanced Science, EarlyView.Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu +18 more
wiley +1 more source
A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time
Advanced Science, EarlyView.This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li +15 more
wiley +1 more source
Environmental Research CommunicationsUsing the results of a follow-up survey circulated to the participants of the Herefordshire Citizens Climate Assembly (HCCA), I compare their stated political identity with the political makeup of the county of Herefordshire (the macro public from which ...
Rachel Coxcoon
doaj +1 more source
MathematicsWe establish a theory whose structure is based on a fixed variable and an algebraic inequality and which improves the well-known least squares theory. The mentioned fixed variable plays a basic role in creating such a theory.
Mohammad Masjed-Jamei
doaj +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Advanced Science, EarlyView.Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Extensions of quadratic transformation identities for hypergeometric functions [PDF]
, 2020 Song-Liang Qiu +2 more
openalex +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
Advanced Science, EarlyView.The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
On the 1/c expansion in 2d CFTs with degenerate operators
Journal of High Energy PhysicsWe analytically determine the large central charge asymptotic expansion of Virasoro conformal blocks entering in four-point functions with external degenerate operators on a sphere in 2d CFTs, and study its resurgence properties as a function of the ...
Agnese Bissi +4 more
doaj +1 more source