Results 171 to 180 of about 1,745,713 (225)

Regulation of mRNA poly(A) tail length governs mammalian body plan formation in gastruloids. [PDF]

Nat Commun
Taborsky D, Valdivia-Francia F, Serrano P, Muzumdar S, Ranjbar N, Llop-Grau L, Tellez G, Gjonlleshaj P, Duré C, Renz PF, Weber R, Yigit M, Ghoshdastider U, Mironov A, Hyams K, Vianello S, Zavolan M, Bar-Nur O, Lutolf MP, Sendoel A.   +19 more
europepmc   +1 more source

Nuclear Functional Divergence and Genetic Basis of Cap Colour Variation Revealed by T2T Genomes of Two Compatible Monokaryons in Pholiota adiposa

Microbial Biotechnology, Volume 19, Issue 11, November 2026.
T2T genomes of two compatible monokaryons reveal nuclear functional specialization and identify two candidate loci on chromosomes 6 and 12 associated with red cap colour in the edible mushroom Pholiota adiposa. ABSTRACT Basidiomycete fungi maintain a dikaryotic state throughout their life cycle, in which two genetically distinct haploid nuclei coexist ...
TianYu Liu, Yangyang Fan, Yuanyuan Liu, Dong Yan, Yu Liu, Shuang Song, Caige Lu, Yuan Guo, Dianpeng Zhang, Shujing Sun, Shouxian Wang, Qi Gao   +11 more
wiley   +1 more source

Developmental-envelope screening and genome-annotation audit prioritize chemical authenticity candidates in commercial <i>Rubus chingii</i> fruit. [PDF]

Food Chem X
Duan W, Wei Z, Gao W, Peng L.
europepmc   +1 more source

FGF13 Alleviates the Aging Process in Mice by Regulating Astrocyte Function in the Medial Prefrontal Cortex via Phafin2 Signaling Pathway

Aging Cell, Volume 25, Issue 11, November 2026.
FGF13 is significantly downregulated in the aging brain, particularly in cortical astrocytes within the medial prefrontal cortex. Genetic knockdown of FGF13 in astrocytes accelerates aging phenotypes and impairs neurological function in mice, while its overexpression effectively delays cognitive decline.
Rui Zheng, Zheng Tu, Yang Fang, Caixiang Zhuang, Yuchao Zhang, Yibo Ying, Zhiyi Feng, Ziyang Jin, Yanyan Zheng, Zhouguang Wang   +9 more
wiley   +1 more source

Screening of cell-type-specific meta-programs for drug repurposing in Alzheimer's disease. [PDF]

Brief Bioinform
Zhang C, Zhang Y, Wu Z, Zhang Y, Xue F, Tan Q, Zhong X, Zhang Y, Zhao Z, Peng Y, Chen H, Li F, Zhang Y.   +12 more
europepmc   +1 more source

A 209‐Site DNA Methylation Predictor of Chronological Age Evaluated Under Empirical and Random Missingness

Aging Cell, Volume 25, Issue 11, November 2026.
A stability‐selected 209‐CpG panel with nearest‐neighbor reconstruction supports chronological‐age prediction from incomplete blood methylation profiles. In held‐out samples under empirically derived missingness masks, reconstruction reduced root‐mean‐square error by 0.365 years versus mean replacement, with larger benefits at higher missingness ...
Xiangteng Zhao, Yanhong Lu, Biqing Huang, Zijie Wang, Tong Yu, Ruoqi Zhao, Shiwen Yu, Shushan Wei, Yeting Zeng   +8 more
wiley   +1 more source

CellLoop: Identifying single-cell 3D genome chromatin loops. [PDF]

Nat Commun
Ye Y, Wang Y, Liu S, Hu Y, Yu L, Wang W, Zhang S, Chen H, Gao L.   +8 more
europepmc   +1 more source

Serum Response Factor Cooperates With Progesterone Receptor to Regulate Oviductal Smooth Muscle Gene Expression During Preimplantation Embryo Transport

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Oviductal smooth muscle contractions are important for preimplantation embryo transport under the regulation of steroid hormone signaling. Deletion of serum response factor (Srf) in progesterone receptor (Pgr)‐expressing cells leads to differential expression of 1670 genes in the mouse oviduct, 306 of which are directly bound by SRF.
Peter F. Lais, Ryan M. Marquardt, San‐Pin Wu, John P. Lydon, Francesco J. DeMayo   +4 more
wiley   +1 more source

A ubiquitin carboxyl-terminal hydrolase facilitates H2A.Z removal in response to phosphate starvation. [PDF]

Nat Commun
Meng F, Xiao X, Ma G, Satheesh V, Wu Q, Zhao Y, Chen H, Lu X, Jiang J, Lei M, Lei M.   +10 more
europepmc   +1 more source

Non‐Central Wishart Random Matrices in Structural Dynamics: A Modal‐Basis Approach

International Journal for Numerical Methods in Engineering, Volume 127, Issue 20, 30 October 2026.
ABSTRACT This article develops a non‐parametric stochastic computational model for linear structural dynamics based on a reduced non‐central Wishart (NCW) random matrix formulation. The objective is to represent uncertainty in the mass and stiffness matrices while preserving the matrix properties required for modal and frequency‐domain analysis ...
Alan Das Mannoosseril, Sondipon Adhikari, H. Murat Panayirci   +2 more
wiley   +1 more source