Results 211 to 220 of about 188,311 (274)

Excess Fructose Intake Activates Hyperinsulinemia and Mitogenic MAPK Pathways in Association With Cellular Stress, Inflammation, and Apoptosis in the Pancreas of Rats

Molecular Nutrition &Food Research, EarlyView.
This study highlights the possible mechanisms underlying the detrimental effects of high‐fructose consumption on pancreatic function. Our findings revealed that dietary high‐fructose in the pancreas causes hyperinsulinemia due to the upregulation of glucose transporter 2 (GLUT2) together with cellular stress and inflammatory markers, thereby stimulates
Ceren Guney, Mehmet Eray Alcigir, Fatma Akar   +2 more
wiley   +1 more source

Bioinformatics Combined With Biological Experiments to Identify the Pathogenetic Link of Type 2 Diabetes for Breast Cancer. [PDF]

Cancer Med
Bao X, Zeng Z, Tang W, Li D, Fan X, Chen K, Wang Y, Ai W, Yang Q, Liu S, Chen T.   +10 more
europepmc   +1 more source

Placental and Cord Blood DNA Methylation Changes Associated With Gestational Diabetes Mellitus in a Marginalized Population: The Untold Role of Saturated Fats

Molecular Nutrition &Food Research, EarlyView.
Excessive intake of saturated fats during pregnancy is associated with DNA hypomethylation in placental and cord blood samples from women affected with gestational diabetes mellitus (GDM), impacting, in particular, the cord blood promoter of ZFP57, a key regulator of early embryonic epigenetic programming.
Fatima Ahmad, Sidra Aftab Uzair, Arun P. Lakshmanan, Shaikha Alabduljabbar, Salma H. Ahmed, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Rose McGready, François Nosten, Damien Chaussabel, Souhaila Al Khodor, Annalisa Terranegra   +13 more
wiley   +1 more source

Corrigendum to "Time to Moderate and Severe Hyperglycemia and Ketonemia Following an Insulin Pump Occlusion". [PDF]

J Diabetes Sci Technol
europepmc   +1 more source

Association between the stress hyperglycemia ratio and all-cause mortality in critically ill patients with T2DM: a retrospective study. [PDF]

Front Endocrinol (Lausanne)
Rui Y, Wu B, Huang C, Li Q.
europepmc   +1 more source

PGC‐1α Activation by Polyphenols: A Pathway to Thermogenesis

Molecular Nutrition &Food Research, EarlyView.
Polyphenols, derived from dietary sources such as berries, undergo digestion and interact with gut microbiota, leading to their metabolization in the liver. This process influences bile acid composition, which in turn activates PGC1α, a key regulator of mitochondrial biogenesis and thermogenesis.
Nicholas Vannuchi, Luciana Pisani
wiley   +1 more source

Association of Oxidative Stress Markers with Incident Hyperglycemia in Gestational Diabetes Mellitus in an Educational Intervention. [PDF]

Nutrients
Ruiz-Martínez ML, Gómez-Díaz RA, Valdez González AL, Ángeles Mejía S, Mondragón González R, Díaz Flores M, Saldaña Espinoza RC, Ramírez-García LA, Díaz Velázquez MF, Wacher NH.   +9 more
europepmc   +1 more source

Preventive Effect of Upland Pigmented Potatoes Against LPS‐Induced Inflammation in THP‐1 Macrophages

Molecular Nutrition &Food Research, EarlyView.
The anti‐inflammatory activity of extracts from three commercial potato varieties cultivated upland was investigated on THP‐1 macrophages insulted with LPS. While the chlorogenic acid (CGA)‐rich extract from Kennebec reduced inflammation only at supraphysiological doses, carotenoid‐rich Desirèe and anthocyanin (ACN)‐rich Bleuet decreased TNF‐α, IL‐1β ...
Marta Toccaceli, Alessandra Marinelli, Federico Ballabio, Laura Bassolino, Roberto Lo Scalzo, Bruno Parisi, Daniela Pacifico, Federica Nicoletti, Carlo Camilloni, Giuseppe Mandolino, Katia Petroni   +10 more
wiley   +1 more source

Effects of glycemic indicators on early neurological outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis. [PDF]

World J Diabetes
Duan ZW, Li ZN, Zhai YJ, Liu TF, Zhang CC, Hu T, Wei XE, Rong LQ, Liu HY.   +8 more
europepmc   +1 more source