Results 51 to 60 of about 12,945 (221)

Hyperhidrosis

TURKDERM, 2011
Hyperhidrosis, which affects nearly 3% of the population, is characterized by excessive sweating due to eccrine sweat gland hyperactivity. It has negative impact on quality of life, and social relations and also may lead to social anxiety disorders.
Onder, Meltem, Aksoy, Gulhan
openaire   +3 more sources

A retrospective review on minimally invasive technique via endoscopic thoracic sympathectomy (ETS) in the treatment of severe primary hyperhidrosis: Experiences from the National Heart Institute, Malaysia [version 1; peer review: 2 approved]

F1000Research, 2018
Background: Hyperhidrosis is due to the hyperactive autonomic stimulation of the sweat glands in response to stress. Primary hyperhidrosis is a common yet psychologically disabling condition.
Ahmad Farouk Musa, Vignaa Prashanth Gandhi, Jeswant Dillon, Rusli Bin Nordin   +3 more
doaj   +1 more source

Clinical and Molecular Effect of the Anti–IL‐18 Antibody Aletekitug in Adults With Atopic Dermatitis

Allergy, Volume 81, Issue 2, Page 539-551, February 2026.
At Week 12, aletekitug was associated with a −68.3% percentage change from baseline in EASI score. Aletekitug improved the transcriptional profile of lesional skin towards that of non‐lesional skin at Week 4 and Week 12. Aletekitug was well‐tolerated; no serious adverse event or death occurred, and no patient withdrew due to an adverse event.
Joanne Ellis, Léa Fortunato, Hannah Wajdner, Ester Del Duca, Joanna Barnard, Joanna C. Betts, Swaroop Bose, John Browning, Núria Buil‐Bruna, Scott Van Buren, Eden David, Scott Dinehart, Puneet Dhawan, Yeriel Estrada, Parima Ghafoori, Kiranmai Gumireddy, Zhenghong Li, Wei Jing Loo, Fiona Lovegrove, Jenny Lowe, Lawrence Charles Parish, Will Powley, Naveen Prasad, Joel Correa Da Rosa, Marieta Ruseva, Neda Shokrian, Farhat Syed, Chun‐Hang Tang, Gabriel K. Wong, John B. Kelly, Nicolas Wisniacki, Iain Uings, Emma Guttman‐Yassky   +32 more
wiley   +1 more source

Efficacy and Safety of OnabotulinumtoxinA for the Treatment of Platysma Prominence: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Platysma prominence (PP) is a common aesthetic concern associated with aging, leading to visible neck bands and loss of jawline definition. OnabotulinumtoxinA has emerged as a minimally invasive treatment; however, data from randomized controlled trials (RCTs) remain fragmented.
Rahman Syed, Ameer Afzal Khan, Suleman Shah, Anfal Khan, Mohammad Idrees, Mohsin Ali, Mohammed Al Sinani, Mohammed Al Maqbali   +7 more
wiley   +1 more source

High Dynamic Range Thin‐Film Resistive Flow Sensors for Monitoring Diverse Biofluids

Advanced Functional Materials, Volume 36, Issue 6, 19 January 2026.
Thin‐film resistive flow sensors with thermoresistive and piezoresistive mechanisms are developed for biofluid monitoring. Fabricated using biocompatible materials and laser micromachining, the devices achieve sub‐millimeter dimensions and a broad dynamic range.
Latifah Almulla, Massimo Mariello, Christopher M Proctor   +2 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

Comparative study of transepidermal water loss in patients with and without hyperhidrosis by closed-chamber measurer in an air-conditioned environment

Einstein (São Paulo)
Objective To evaluate the difference in transepidermal water loss in patients diagnosed with hyperhidrosis and healthy subjects, in an air-conditioned environment.
Andre Miotto, Pedro Augusto Antunes Honda, Thiago Gangi Bachichi, Caio Santos Holanda, Ernesto Evangelista Neto, João Alessio Juliano Perfeito, Luiz Eduardo Villaça Leão, Altair da Silva Costa Jr   +7 more
doaj   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Head &Neck, Volume 48, Issue 1, Page 160-174, January 2026.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti, Joseph M. Curry, Jennifer Johnson, Michael Kwon, Shirley Y. Su, Francisco Civantos, Coral Olazagasti, Joseph Valentino, Susanne M. Arnold, R. Bryan Bell, Michael K. Gibson, Kyle Mannion, Kathryn M. Van Abel, Katharine A. Price, Haiying Dong, Amy H. Thorne, Toshiaki Suzuki, Ann M. Gillenwater   +17 more
wiley   +1 more source

Role of video-assisted thoracoscopic sympathectomy in the treatment of primary hyperhidrosis

São Paulo Medical Journal
CONTEXT: Essential hyperhidrosis is a frequent disorder causing significant functional impairment. The advent and development of video-assisted thoracoscopic techniques now allows thoracic sympathectomy to be carried out precisely and safety with good ...
Luiz Eduardo Villaça Leão, Renato de Oliveira, Renuzza Szulc, Jair de Jesus Mari, Pedro Luis Reis Crotti, José Julio Saraiva Gonçalves   +5 more
doaj   +1 more source

Decreased work productivity due to primary palmar hyperhidrosis. What is the cost?

Skin Health and Disease, 2021
J. K. Kristensen, C. Nielsen
doaj   +1 more source