Results 101 to 110 of about 38,804 (257)

Hyperhomocysteinemia and Endothelial Dysfunction [PDF]

Current Hypertension Reviews, 2009
Hyperhomocysteinemia (HHcy) is a significant and independent risk factor for cardiovascular diseases. Endothelial dysfunction (ED) is the earliest indicator of atherosclerosis and vascular diseases. We and others have shown that HHcy induced ED in human and in animal models of HHcy induced by either high-methionine load or genetic deficiency.
Zhongjian, Cheng, Xiaofeng, Yang, Hong, Wang   +2 more
openaire   +2 more sources

Ly6C+ Inflammatory Monocyte Differentiation Partially Mediates Hyperhomocysteinemia-Induced Vascular Dysfunction in Type 2 Diabetic db/db Mice.

Arteriosclerosis, Thrombosis and Vascular Biology, 2019
OBJECTIVE Hyperhomocysteinemia (HHcy) is a potent risk factor for diabetic cardiovascular diseases. We have previously reported that hyperhomocysteinemia potentiates type 1 diabetes mellitus-induced inflammatory monocyte differentiation, vascular ...
Pu Fang, Xinyuan Li, Huimin Shan, J. Saredy, Ramón Cueto, Jixiang Xia, Xiaohua Jiang, Xiaofeng Yang, Hong Wang   +8 more
semanticscholar   +1 more source

Vitamin B12 and Reproductive Health: Clinical Insights, Emerging Mechanistic Understanding, and Nutritional Aspects

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT Epidemiological data from assisted reproductive technologies (ART) link vitamin B12 (VitB12) deficiency to shorter gestation, low birth weight, and reduced live birth rates. VitB12 also plays a critical role in fertility for both sexes by supporting gamete quality.
Aimee Rachel Mathew, Erisa Selita, Chiara Regano, Claudia Bianco, Veronica Corsetti, Virve Cavallucci, Sandra Moreno, Ada Maria Tata, Marco Fidaleo   +8 more
wiley   +1 more source

Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S‐sulfhydration in ApoE‐knockout atherosclerotic mice

British Journal of Pharmacology, 2019
Hydrogen sulfide donors can block the cardiovascular injury of hyperhomocysteinemia. H2S also lowers serum homocysteine in rats with mild hyperhomocysteinemia, but the pharmacological mechanism is unknown.
Jinhui Fan, Fengjiao Zheng, Shuangyue Li, Cangting Cui, Shan Jiang, Jinchao Zhang, Jun Cai, Qinghua Cui, Jichun Yang, Xinjing Tang, Guoheng Xu, B. Geng   +11 more
semanticscholar   +1 more source

Analysis of DTC nutrigenetic services in Italy: state of the art, agreement to the ESHG statement and future outlooks [PDF]

, 2012
Background: In both USA and Europe operate companies selling Direct-to-consumer genetic tests (DTC). These tests are offered to healthy people aiming to identify predispositions to complex diseases and to take preventive measures.
Alessandra Cianflone, Antonella Monticelli, Fabio Acquaviva, Imma Castaldo, Michele Pinelli, Paola Vergara, Sergio Cocozza, Vincenzo Cinque   +7 more
core   +1 more source

Avascular Necrosis and Minimal Trauma Fractures in Telomere Biology Disorders

Clinical Genetics, Volume 109, Issue 2, Page 286-293, February 2026.
Avascular Necrosis (AVN) and Minimal Trauma Fractures (MTF) cause significant morbidity in people with Telomere Biology Disorders (TBDs). They occur more frequently in young patients and in those with autosomal recessive (AR) or X‐linked recessive (XLR) than in autosomal dominant (AD) genotypes.
Arman M. Niknafs, Neelam Giri, Marena R. Niewisch, Sharon A. Savage   +3 more
wiley   +1 more source

Global Research Trends and Hotspots in Cerebral Small Vessel Disease‐Related Cognitive Impairment: A Bibliometric Analysis (2001–2024)

Brain and Behavior, Volume 16, Issue 1, January 2026.
This bibliometric study systematically analyzed 1074 publications in the field of CSVD‐CI from 2001 to 2024. The research reveals three evolutionary phases and identifies four core research clusters: pathophysiological mechanisms, neuroimaging biomarkers, clinical assessment, and therapeutic interventions.
Kuihua Wang, Xiaohui Ji, Hui Li, Xiaoyang Wang, Xiaoyue Jin, YanJun Lin, Qiao Wang, Haizhen Xu, Jianxin Ye, Xiaoping Cui, Yonghui Liang   +10 more
wiley   +1 more source

Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with macrocytosis

Journal of the Formosan Medical Association, 2019
Background/Purpose: Macrocytosis is defined as having the mean corpuscular volume (MCV) ≧ 100 fL. This study evaluated whether 41 atrophic glossitis (AG) patients with macrocytosis had significantly higher frequencies of anemia, hematinic deficiencies ...
Chun-Pin Chiang, Yu-Hsueh Wu, Julia Yu-Fong Chang, Yi-Ping Wang, Yang-Che Wu, Andy Sun   +5 more
doaj   +1 more source

An uncommon presentation of hyperhomocysteinemia and vitamin B12 deficiency: a case report

Journal of Medical Case Reports, 2019
Introduction Cerebral venous thrombosis is relatively rare and characterized by a wide spectrum of clinical features. It is more common in young adults with women affected more than men.
Vinay Kapur, Sanjay D’Cruz, Ravinder Kaur   +2 more
doaj   +1 more source

Serum homocysteine, vitamin B 12 and folic acid levels in different types of glaucoma [PDF]

, 2006
Background This study was performed to compare levels of serum homocysteine (Hcy), vitamin B12 and folic acid in patients with primary open-angle glaucoma (POAG), pseudoexfoliative glaucoma (PEXG), normotensive glaucoma (NTG) and healthy controls ...
Tongabay Cumurcu, Semsettin Sahin, Erdinc Aydin, J Flammer, SS Hayreh, V Bousse, M Cahill, P Pianka, A Lowenstein, BA Brown, JD Finkelstein, PM Ueland, MJ Stampfer, IJ Perry, AA Warsi, F Leblhuber, S Bleich, I Leibovitch, RM Vessani, T Puustjarvi, O Altintas, G Wang, T Brunelli, GJ Hankey, GJ Hankey, Z Bagi, GG Koliakos, BA Sela, N Asano, K Karjalainen, C Cursiefen, p Mitchell, S Schumacher, LP Repo   +33 more
core   +1 more source