On the Origin of Western Diet Pathologies [PDF]
The ratio of the two sulfur-containing amino acids, methionine (Met) and cysteine (Cys), may be a determining factor for which foods contribute to longevity and health. It is shown here that substantially more Met than Cys is consistently found in foods,
John Schloss
core +1 more source
Behind only Alzheimer’s disease, vascular contributions to cognitive impairment and dementia (VCID) is the second most common cause of dementia, affecting roughly 10–40% of dementia patients. While there is no cure for VCID, several risk factors for VCID,
Brittani R. Price +2 more
semanticscholar +1 more source
Homocysteine treatment alters redox capacity of both endothelial and tumor cells [PDF]
Homocysteine is a non-proteinogenic amino acid playing key roles in two interconnected metabolic pathways, namely, the activated methyl cycle and the linear trans-sulfuration pathway that allows the conversion of methionine to cysteine.
Cárdenas, Casimiro +5 more
core
Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid [PDF]
Background: There is evidence that homocysteine contributes to various neurodegenerative disorders. Objective: To assess the values of homocysteine in patients with Creutzfeldt-Jakob disease (CJD) in both cerebrospinal fluid (CSF) and plasma.
Bottiglieri T +11 more
core +1 more source
Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study
Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano +5 more
wiley +1 more source
PENGARUH PEMBERIAN FOLAT TERHADAP KADAR HOMOSISTEIN SERUM DAN MALONDIALDEHID PLASMA STUDI EKSPERIMENTAL PADA TIKUS SPRAGUE DAWLEY YANG DIINDUKSI STREPTOZOTOCIN [PDF]
Background: Diabetes mellitus (DM) associated with increased level and oxidative activity of homocystein (Hcy) that cause oxidative stress. Plasma malondialdehyde (MDA) known as a marker of oxidative stress.
Wahyuni, Emmy
core
Type 2 Diabetes From the Perspective of Telomere Biology
This graphical abstract illustrates the bidirectional relationship between the telomere/telomerase system and T2DM: telomere attrition contributes to pancreatic β‐cell dysfunction and insulin resistance through mechanisms such as oxidative stress and apoptosis, while T2DM‐related hyperglycemia and chronic inflammation further exacerbate telomere damage.
Hongye Cao +3 more
wiley +1 more source
ObjectiveThe risk of venous thromboembolism in patients with mental illness has been insufficiently addressed. This study aimed to assess the correlation between hyperhomocysteinemia and venous thromboembolism prevalence among this population ...
Jiaoyan Wang +5 more
doaj +1 more source
Incidence of hyperhomocysteinemia and MTHFR C677T polymorphism among young patients with acute myocardial infarction [PDF]
Hyperhomocysteinemia is considered an independent risk factor for premature cardiovascular disease. Mutation MTHFR C677T reduces the activity of methylene tetrahydrofolatereductase and may cause hyperhomocysteinemia.
Beletić Anđelo +9 more
doaj
Homocysteine, MTHFR C677T gene polymorphism, folic acid and vitamin B 12 in patients with retinal vein occlusion [PDF]
Background Many available data have suggested that hyperhomocysteinaemia, an established independent risk factor for thrombosis (arterial and venous), may be associated with an increased risk of retinal vein occlusion (RVO).
Paola Terrazzi +7 more
core +2 more sources

