Results 61 to 70 of about 12,970 (183)

An uncommon presentation of hyperhomocysteinemia and vitamin B12 deficiency: a case report

Journal of Medical Case Reports, 2019
Introduction Cerebral venous thrombosis is relatively rare and characterized by a wide spectrum of clinical features. It is more common in young adults with women affected more than men.
Vinay Kapur, Sanjay D’Cruz, Ravinder Kaur   +2 more
doaj   +1 more source

Hyperhomocysteinemia and Thrombosis: An Overview

Archives of Pathology & Laboratory Medicine, 2007
Abstract Context. —Homocysteine, a sulfur-containing amino acid, absent in natural diets, is a metabolic intermediary in transmethylation and transsulfuration reactions. Such reactions are essential to normal cellular growth, differentiation, and function. Excess homocysteine is associated with
Mohamed M, Eldibany, Joseph A, Caprini
openaire   +2 more sources

TARDBP Mediates the MAP3K11/SLC3A2/GPX4 Axis in Alzheimer's Disease Rats by Enhancing KRAS mRNA Stability

Journal of Cellular and Molecular Medicine, Volume 30, Issue 10, May 2026.
ABSTRACT Ferroptosis is an emerging pathological mechanism in Alzheimer's disease (AD). The aim of the present study was to investigate the potential mechanisms by which TARDBP is involved in AD by promoting ferroptosis. An AD rat model was established by injecting homocysteine (Hcy).
QiTao Zhao, YaDong Yu, FuJiang Wang, Ya Wang, Peng Shao, LianDong Zhao   +5 more
wiley   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, Volume 13, Issue 4, Page 819-826, April 2026.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Corrective effects of hepatotoxicity by hepatic Dyrk1a gene delivery in mice with intermediate hyperhomocysteinemia

Molecular Genetics and Metabolism Reports, 2015
Hyperhomocysteinemia results from hepatic metabolism dysfunction and is characterized by a high plasma homocysteine level, which is also an independent risk factor for cardiovascular disease.
Alizée Latour, Sacha Salameh, Christel Carbonne, Fabrice Daubigney, Jean-Louis Paul, Micheline Kergoat, Valérie Autier, Jean-Maurice Delabar, Bart De Geest, Nathalie Janel   +9 more
doaj   +1 more source

Hyperhomocysteinemia: Clinical Insights [PDF]

Journal of Central Nervous System Disease, 2020
Homocysteine (Hcy) is a sulfhydryl-containing amino acid, and intermediate metabolite formed in metabolising methionine (Met) to cysteine (Cys); defective Met metabolism can increase Hcy. The effect of hyperhomocysteinemia (HHcy) on human health, is well described and associated with multiple clinical conditions. HHcy is considered to be an independent
openaire   +3 more sources

Accelerated epigenetic aging as a modifier of homocysteine‐associated cognitive decline: Findings from NHANES

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Hyperhomocysteinemia represents a modifiable risk factor for cognitive decline and dementia, yet the role of epigenetic aging mechanisms in mediating this association remain poorly characterized, limiting development of targeted interventions.
Haoxuan Li, Yuhan Chen, Zhe Wang, Yankun Wang, Ran Bi, Jiayu Hou, Huan Chen, Zixuan Zhang, Zhenhao Guo, Zhuo Chen, Huixian Cui, Sha Li   +11 more
wiley   +1 more source

Study of the Functional State of the Left Ventricular Myocardium in Patients with Coronary Artery Disease with Impaired Metabolism of Homocysteine and Vitamin D

Український журнал серцево-судинної хірургії, 2020
To date, it has been established that in the progression of coronary artery disease (CAD) and its complications, an increase in the level of homocysteine and hypovitaminosis D are essential. However, medical publications do not adequately cover the study
O. S. Nikonenko, A. O. Nikonenko, K. O. Chmul, O. V. Molodan, V. V. Osaulenko   +4 more
doaj   +1 more source

Homocysteine and cardiovascular disease

حیات, 2000
Hyperhomocysteinemia is a condition which , in the absence of kidney disease , indicates a disturpted sulfur amino acid metabolism , either because of vitamin deficiency (folate , B12 and B6 ) or a genetic defect. Epidemiologicevidence suggests that mild
p yavari
doaj  

Folic Acid and Vitamins B12 Levels and Their Correlation in Cigarette Smoker with Hyperhomocysteinemia [PDF]

Al Ameen Journal of Medical Sciences, 2011
To estimate the levels of folic acid and vitamin B12 and their relationship in cigarette smoker with hyperhomocysteinemia. 30 male cigarette smokers in the age group of 30 to 60 years were studied for estimation of serum folic acid, vitamin B12 and total
Shahid A. Mujawar* and Vinayak W. Patil
doaj