Results 61 to 70 of about 13,048 (184)

Hyperhomocysteinemia and Thrombosis: An Overview

open access: yesArchives of Pathology & Laboratory Medicine, 2007
Abstract Context. —Homocysteine, a sulfur-containing amino acid, absent in natural diets, is a metabolic intermediary in transmethylation and transsulfuration reactions. Such reactions are essential to normal cellular growth, differentiation, and function. Excess homocysteine is associated with
Mohamed M, Eldibany, Joseph A, Caprini
openaire   +2 more sources

Hyperhomocysteinemia: Clinical Insights [PDF]

open access: yesJournal of Central Nervous System Disease, 2020
Homocysteine (Hcy) is a sulfhydryl-containing amino acid, and intermediate metabolite formed in metabolising methionine (Met) to cysteine (Cys); defective Met metabolism can increase Hcy. The effect of hyperhomocysteinemia (HHcy) on human health, is well described and associated with multiple clinical conditions. HHcy is considered to be an independent
openaire   +3 more sources

Corrective effects of hepatotoxicity by hepatic Dyrk1a gene delivery in mice with intermediate hyperhomocysteinemia

open access: yesMolecular Genetics and Metabolism Reports, 2015
Hyperhomocysteinemia results from hepatic metabolism dysfunction and is characterized by a high plasma homocysteine level, which is also an independent risk factor for cardiovascular disease.
Alizée Latour   +9 more
doaj   +1 more source

Pernicious Anemia and Helicobacter pylori Infection: What a Hematologist Needs to Know?

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Helicobacter pylori infection and the possible underlying mechanism of parietal cell damage, and progression to pernicious anemia. ABSTRACT This case report emphasizes the importance of early detection and prompt treatment of Helicobacter pylori (H. pylori) as a reversible cause of autoimmune gastritis and its associated vitamin B‐12 deficiency.
Eisha Saadat   +2 more
wiley   +1 more source

Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative atrophic glossitis patients

open access: yesJournal of the Formosan Medical Association, 2019
Background/Purpose: Approximately 27% of atrophic glossitis (AG) patients have the serum gastric parietal cell antibody (GPCA) positivity. This study assessed whether the serum GPCA or AG itself was a significant factor causing anemia, hematinic ...
Chun-Pin Chiang   +5 more
doaj   +1 more source

Study of the Functional State of the Left Ventricular Myocardium in Patients with Coronary Artery Disease with Impaired Metabolism of Homocysteine and Vitamin D

open access: yesУкраїнський журнал серцево-судинної хірургії, 2020
To date, it has been established that in the progression of coronary artery disease (CAD) and its complications, an increase in the level of homocysteine and hypovitaminosis D are essential. However, medical publications do not adequately cover the study
O. S. Nikonenko   +4 more
doaj   +1 more source

Novel Insights Into the Association Between Parkinson's Disease and Constipation: Role of SHMT2 as a Promising Biomarker

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This study integrated bioinformatics analysis, cellular models, and PD/constipation mouse models to identify SHMT2 as a key shared biomarker linking Parkinson's disease and constipation. SHMT2 upregulation was validated in dopaminergic neurons and the enteric nervous system, highlighting its potential role in gut–brain axis dysfunction.
Jiehua Su   +10 more
wiley   +1 more source

Folic Acid and Vitamins B12 Levels and Their Correlation in Cigarette Smoker with Hyperhomocysteinemia [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2011
To estimate the levels of folic acid and vitamin B12 and their relationship in cigarette smoker with hyperhomocysteinemia. 30 male cigarette smokers in the age group of 30 to 60 years were studied for estimation of serum folic acid, vitamin B12 and total
Shahid A. Mujawar* and Vinayak W. Patil
doaj  

Homocysteine and cardiovascular disease

open access: yesحیات, 2000
Hyperhomocysteinemia is a condition which , in the absence of kidney disease , indicates a disturpted sulfur amino acid metabolism , either because of vitamin deficiency (folate , B12 and B6 ) or a genetic defect. Epidemiologicevidence suggests that mild
p yavari
doaj  

The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels

open access: yesHaematologica, 2007
In a large retrospective study of thrombophilic families, we analyzed 405 relatives of patients, hypothesizing that hyperhomocysteinemia and elevated factor VIII levels are closely related. Median factor VIII levels in hyperhomocysteinemic relatives were
Willem M. Lijfering   +3 more
doaj   +1 more source

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