Results 61 to 70 of about 13,048 (184)
Hyperhomocysteinemia and Thrombosis: An Overview
Abstract Context. —Homocysteine, a sulfur-containing amino acid, absent in natural diets, is a metabolic intermediary in transmethylation and transsulfuration reactions. Such reactions are essential to normal cellular growth, differentiation, and function. Excess homocysteine is associated with
Mohamed M, Eldibany, Joseph A, Caprini
openaire +2 more sources
Hyperhomocysteinemia: Clinical Insights [PDF]
Homocysteine (Hcy) is a sulfhydryl-containing amino acid, and intermediate metabolite formed in metabolising methionine (Met) to cysteine (Cys); defective Met metabolism can increase Hcy. The effect of hyperhomocysteinemia (HHcy) on human health, is well described and associated with multiple clinical conditions. HHcy is considered to be an independent
openaire +3 more sources
Hyperhomocysteinemia results from hepatic metabolism dysfunction and is characterized by a high plasma homocysteine level, which is also an independent risk factor for cardiovascular disease.
Alizée Latour +9 more
doaj +1 more source
Pernicious Anemia and Helicobacter pylori Infection: What a Hematologist Needs to Know?
Helicobacter pylori infection and the possible underlying mechanism of parietal cell damage, and progression to pernicious anemia. ABSTRACT This case report emphasizes the importance of early detection and prompt treatment of Helicobacter pylori (H. pylori) as a reversible cause of autoimmune gastritis and its associated vitamin B‐12 deficiency.
Eisha Saadat +2 more
wiley +1 more source
Background/Purpose: Approximately 27% of atrophic glossitis (AG) patients have the serum gastric parietal cell antibody (GPCA) positivity. This study assessed whether the serum GPCA or AG itself was a significant factor causing anemia, hematinic ...
Chun-Pin Chiang +5 more
doaj +1 more source
To date, it has been established that in the progression of coronary artery disease (CAD) and its complications, an increase in the level of homocysteine and hypovitaminosis D are essential. However, medical publications do not adequately cover the study
O. S. Nikonenko +4 more
doaj +1 more source
This study integrated bioinformatics analysis, cellular models, and PD/constipation mouse models to identify SHMT2 as a key shared biomarker linking Parkinson's disease and constipation. SHMT2 upregulation was validated in dopaminergic neurons and the enteric nervous system, highlighting its potential role in gut–brain axis dysfunction.
Jiehua Su +10 more
wiley +1 more source
Folic Acid and Vitamins B12 Levels and Their Correlation in Cigarette Smoker with Hyperhomocysteinemia [PDF]
To estimate the levels of folic acid and vitamin B12 and their relationship in cigarette smoker with hyperhomocysteinemia. 30 male cigarette smokers in the age group of 30 to 60 years were studied for estimation of serum folic acid, vitamin B12 and total
Shahid A. Mujawar* and Vinayak W. Patil
doaj
Homocysteine and cardiovascular disease
Hyperhomocysteinemia is a condition which , in the absence of kidney disease , indicates a disturpted sulfur amino acid metabolism , either because of vitamin deficiency (folate , B12 and B6 ) or a genetic defect. Epidemiologicevidence suggests that mild
p yavari
doaj
In a large retrospective study of thrombophilic families, we analyzed 405 relatives of patients, hypothesizing that hyperhomocysteinemia and elevated factor VIII levels are closely related. Median factor VIII levels in hyperhomocysteinemic relatives were
Willem M. Lijfering +3 more
doaj +1 more source

