Results 51 to 60 of about 12,970 (183)

Do We Need to Monitor B‐Vitamins and Homocysteine During Initiation of Foslevodopa/Foscarbidopa Therapy?

open access: yes
Movement Disorders, EarlyView.
Aida Shaghaghi‐Zadeh   +8 more
wiley   +1 more source

Novel Insights Into the Association Between Parkinson's Disease and Constipation: Role of SHMT2 as a Promising Biomarker

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This study integrated bioinformatics analysis, cellular models, and PD/constipation mouse models to identify SHMT2 as a key shared biomarker linking Parkinson's disease and constipation. SHMT2 upregulation was validated in dopaminergic neurons and the enteric nervous system, highlighting its potential role in gut–brain axis dysfunction.
Jiehua Su   +10 more
wiley   +1 more source

Hyperhomocysteinemia, intravascular hemostasis disturbances, and clinical course of myocardial infarction

open access: yesРоссийский кардиологический журнал, 2007
The article is devoted to associations between hyperhomocysteinemia and intravascular hemostasis disturbances in myocardial infarction (MI) patients. The role of these disturbances in post-MI angina and recurrent MI development is analyzed.
V. A. Lusov   +2 more
doaj  

Optimal Surgical Timing and Outcome Prediction in Hemorrhagic Moyamoya Disease: A Retrospective Cohort Study

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This cohort study developed and validated the first prognostic nomogram for hemorrhagic MMD, incorporating five independent predictors including a defined optimal surgical window of 3 to 6 months. The model demonstrated good discrimination and aids in risk stratification for clinical monitoring.
Qingbao Guo   +6 more
wiley   +1 more source

Comparison of oxidative stress biomarkers in hypertensive patients with or without hyperhomocysteinemia

open access: yesClinical and Experimental Hypertension, 2018
Hyperhomocysteinemia is an independent risk factor for cardiovascular impairment in hypertension. Oxidative stress is important in the molecular mechanisms associated with hypertension, but there are few studies focusing on the comparison of oxidative ...
Gang Guo   +4 more
doaj   +1 more source

Significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients

open access: yesJournal of the Formosan Medical Association, 2018
Background/Purpose: Atrophic glossitis (AG) patients are prone to have anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity.
Chun-Pin Chiang   +5 more
doaj   +1 more source

Histone Modifications in Cardiovascular Disease: Mechanisms and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 5, May 2026.
This graphical abstract summarizes how classical and emerging histone posttranslational modifications (PTMs), together with their chromatin regulators (writers, erasers, and readers), govern major pathobiological programs in cardiovascular disease.
Yu Zheng   +8 more
wiley   +1 more source

Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with macrocytosis

open access: yesJournal of the Formosan Medical Association, 2019
Background/Purpose: Macrocytosis is defined as having the mean corpuscular volume (MCV) ≧ 100 fL. This study evaluated whether 41 atrophic glossitis (AG) patients with macrocytosis had significantly higher frequencies of anemia, hematinic deficiencies ...
Chun-Pin Chiang   +5 more
doaj   +1 more source

Does serum gastric parietal cell antibody titer have influence on anemia and vitamin B12 deficiency in atrophic glossitis patients?

open access: yesJournal of the Formosan Medical Association, 2020
Background/Purpose: Our previous study found 284 gastric parietal cell antibody (GPCA)-positive atrophic glossitis (AG) patients (so-called GPCA+AG patients in this study) in a group of 1064 AG patients.
Chun-Pin Chiang   +5 more
doaj   +1 more source

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu   +6 more
wiley   +1 more source

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