Results 41 to 50 of about 13,370 (136)

Moderate hyperhomocysteinemia is a highly prevalent defect in Spanish patients with venous thromboembolic disease

open access: yesHaematologica, 1998
Recent studies suggest that mild hyperhomocysteinemia may be a risk factor for venous thromboembolic disease (VTED). In this work we evaluated the prevalence of moderate hyperhomocysteinemia in patients with VTED in our area.
Y Gonzalez   +5 more
doaj  

Mechanistic Insights Into Hepatotoxicity‐Induced Liver Cirrhosis and Anemia: Iron Dysregulation, the Hepcidin–Ferroportin Axis, and Emerging Therapeutic Strategies

open access: yesOrgan Medicine, Volume 3, Issue 3, Page 171-185, September 2026.
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley   +1 more source

Efficacy and Safety of Ultra‐Low Starting Dose Febuxostat Titration in Male Patients With Primary Gout

open access: yesInternational Journal of Rheumatic Diseases, Volume 29, Issue 9, September 2026.
ABSTRACT Background Since gout is a common metabolic arthritis caused by urate crystal deposition, urate‐lowering therapy (ULT) is clearly indicated, but the initiation of ULT frequently causes paradoxical acute flares that in turn impair patient adherence.
Sun Huizhen   +5 more
wiley   +1 more source

Hyperhomocysteinemia, intravascular hemostasis disturbances, and clinical course of myocardial infarction

open access: yesРоссийский кардиологический журнал, 2007
The article is devoted to associations between hyperhomocysteinemia and intravascular hemostasis disturbances in myocardial infarction (MI) patients. The role of these disturbances in post-MI angina and recurrent MI development is analyzed.
V. A. Lusov   +2 more
doaj  

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 7, Page 1518-1523, July 2026.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia

open access: yesBrain Sciences, 2019
The incidence of dementia is on the rise and expected to continue to increase in the foreseeable future. Two of the most common subtypes of dementia are Alzheimer’s subtype and vascular dementia.
Christian E. Cajavilca   +2 more
doaj   +1 more source

Cerebral Venous Thrombosis in a Young Adult: Challenges in Diagnosing and Managing Risk Factors in a Resource‐Limited Setting

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cerebral venous thrombosis should be suspected in young patients with severe headache and seizures, even without clear risk factors. In resource‐limited settings, early imaging and prompt anticoagulation can significantly improve outcomes despite incomplete thrombophilia workup.
Filmon Tesfay   +3 more
wiley   +1 more source

Comparison of oxidative stress biomarkers in hypertensive patients with or without hyperhomocysteinemia

open access: yesClinical and Experimental Hypertension, 2018
Hyperhomocysteinemia is an independent risk factor for cardiovascular impairment in hypertension. Oxidative stress is important in the molecular mechanisms associated with hypertension, but there are few studies focusing on the comparison of oxidative ...
Gang Guo   +4 more
doaj   +1 more source

An uncommon presentation of hyperhomocysteinemia and vitamin B12 deficiency: a case report

open access: yesJournal of Medical Case Reports, 2019
Introduction Cerebral venous thrombosis is relatively rare and characterized by a wide spectrum of clinical features. It is more common in young adults with women affected more than men.
Vinay Kapur   +2 more
doaj   +1 more source

Does serum gastric parietal cell antibody titer have influence on anemia and vitamin B12 deficiency in atrophic glossitis patients?

open access: yesJournal of the Formosan Medical Association, 2020
Background/Purpose: Our previous study found 284 gastric parietal cell antibody (GPCA)-positive atrophic glossitis (AG) patients (so-called GPCA+AG patients in this study) in a group of 1064 AG patients.
Chun-Pin Chiang   +5 more
doaj   +1 more source

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