Results 41 to 50 of about 13,048 (184)

Hyperhomocysteinemia is associated with the risk of venous thromboembolism in patients with mental illness: a case-control study

Frontiers in Psychiatry
ObjectiveThe risk of venous thromboembolism in patients with mental illness has been insufficiently addressed. This study aimed to assess the correlation between hyperhomocysteinemia and venous thromboembolism prevalence among this population ...
Jiaoyan Wang, Jiaoyan Wang, Yingchun Zhang, Keming Ren, Yeping Li, Kejing Ying   +5 more
doaj   +1 more source

Alliinase: A Comprehensive Review of the Pivotal Enzyme in Garlic Chemistry and Its Applications

Food Frontiers, Volume 7, Issue 4, July 2026.
Garlic crude extract was purified to obtain alliinase, which catalyzes alliin hydrolysis to release allicin. The free and immobilized alliinase shows potential applications in food, biotechnology, pharmaceuticals, health products, and biosensors. ABSTRACT Alliinase is a pyridoxal 5′‐phosphate (PLP)‐dependent lyase that serves as the cornerstone of the ...
Zhenlin Han, Tian Ye, Yantian Tang, Guodong Su, Jiazhou Li, Ningyang Li   +5 more
wiley   +1 more source

Hyperhomocysteinemia and Lupus Nephritis [PDF]

Cureus, 2019
Background  In SLE, both disease-specific and traditional risk factors are important. Increased serum homocysteine levels are seen in approximately 15% of patients with systemic lupus erythematosus and are associated with an increased risk of atherothrombotic events in this population.
Timlin, Homa, Manno, Rebecca, Douglas, Homeyra   +2 more
openaire   +2 more sources

Hyperhomocysteinemia and the risk of silent brain infarcts: systematic review and meta-analysis

Journal of Stroke and Cerebrovascular Diseases
Background and Purpose: Previous studies have reported differences in homocysteine levels between patients with and without silent brain infarction. However, evidence comparing silent brain infarct rates by hyperhomocysteinemia status remains limited. We
Mahmoud Afia, Alaa Abdelraheam, Sai Krishna Vallamchetla, Doaa Q Ramadan, Stephen W. English, Michelle P. Lin   +5 more
doaj   +1 more source

Incidence of hyperhomocysteinemia and MTHFR C677T polymorphism among young patients with acute myocardial infarction [PDF]

Journal of Medical Biochemistry, 2009
Hyperhomocysteinemia is considered an independent risk factor for premature cardiovascular disease. Mutation MTHFR C677T reduces the activity of methylene tetrahydrofolatereductase and may cause hyperhomocysteinemia.
Beletić Anđelo, Mirković Duško, Antonijević Nebojša, Đorđević Valentina, Šango Violeta, Jakovljević Branko, Peruničić Jovan, Ilić Mirka, Vasiljević Zorana, Majkić-Singh Nada   +9 more
doaj  

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Do We Need to Monitor B‐Vitamins and Homocysteine During Initiation of Foslevodopa/Foscarbidopa Therapy?

Movement Disorders, EarlyView.
Aida Shaghaghi‐Zadeh, Matthias Höllerhage, Florian Wegner, Lan Ye, Ishana Schneidereit, Tobias Hegelmaier, Rebecca Jacob, Christoph Schrader, Martin Klietz   +8 more
wiley   +1 more source

Meeting report for the Second International Conference on Unconventional Animal Models of Alzheimer's Disease and Aging (UAMAA 2026)

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.
Abstract The Second International Conference on Unconventional Animal Models of Alzheimer's Disease and Aging (UAMAA 2026) was held February 9 through 11, 2026, in Irvine, California. Building upon the inaugural meeting in Santiago, Chile (2023), this conference expanded an international effort to develop, characterize, and rigorously evaluate non ...
Jane Alshami, Ginny Wu, B. Maximiliano Garduño, Afonso C. Silva, Stacey J. Sukoff Rizzo, Patricia Cogram, Xiangmin Xu   +6 more
wiley   +1 more source

MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia

Brain Sciences, 2019
The incidence of dementia is on the rise and expected to continue to increase in the foreseeable future. Two of the most common subtypes of dementia are Alzheimer’s subtype and vascular dementia.
Christian E. Cajavilca, Rajan R. Gadhia, Gustavo C. Román   +2 more
doaj   +1 more source