Results 41 to 50 of about 12,970 (183)

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Neonates born at term with periventricular haemorrhagic infarction: Risk factors and clinical presentation

Developmental Medicine &Child Neurology, Volume 68, Issue 7, Page 1005-1012, July 2026.
This case series describes infants born near term with periventricular hemorrhagic infarction (PVHI), highlighting seizures as a common early symptom. Neonatal complications during delivery and pro‐thrombotic genetic mutations were slightly more common. MRI‐classified involvement was predominantly in the caudate vein territory.
Aleksandra Zaykova, Jeroen Dudink, Floris Groenendaal, Maarten H. Lequin, Manon J.N.L. Benders, Maria Luisa Tataranno, Elise Roze   +6 more
wiley   +1 more source

Hyperhomocysteinemia and Endothelial Dysfunction [PDF]

Current Hypertension Reviews, 2009
Hyperhomocysteinemia (HHcy) is a significant and independent risk factor for cardiovascular diseases. Endothelial dysfunction (ED) is the earliest indicator of atherosclerosis and vascular diseases. We and others have shown that HHcy induced ED in human and in animal models of HHcy induced by either high-methionine load or genetic deficiency.
Zhongjian, Cheng, Xiaofeng, Yang, Hong, Wang   +2 more
openaire   +2 more sources

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, Volume 13, Issue 11, 9 June 2026.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source

Hyperhomocysteinemia is associated with the risk of venous thromboembolism in patients with mental illness: a case-control study

Frontiers in Psychiatry
ObjectiveThe risk of venous thromboembolism in patients with mental illness has been insufficiently addressed. This study aimed to assess the correlation between hyperhomocysteinemia and venous thromboembolism prevalence among this population ...
Jiaoyan Wang, Jiaoyan Wang, Yingchun Zhang, Keming Ren, Yeping Li, Kejing Ying   +5 more
doaj   +1 more source

Incidence of hyperhomocysteinemia and MTHFR C677T polymorphism among young patients with acute myocardial infarction [PDF]

Journal of Medical Biochemistry, 2009
Hyperhomocysteinemia is considered an independent risk factor for premature cardiovascular disease. Mutation MTHFR C677T reduces the activity of methylene tetrahydrofolatereductase and may cause hyperhomocysteinemia.
Beletić Anđelo, Mirković Duško, Antonijević Nebojša, Đorđević Valentina, Šango Violeta, Jakovljević Branko, Peruničić Jovan, Ilić Mirka, Vasiljević Zorana, Majkić-Singh Nada   +9 more
doaj  

Hyperhomocysteinemia and Lupus Nephritis [PDF]

Cureus, 2019
Background  In SLE, both disease-specific and traditional risk factors are important. Increased serum homocysteine levels are seen in approximately 15% of patients with systemic lupus erythematosus and are associated with an increased risk of atherothrombotic events in this population.
Timlin, Homa, Manno, Rebecca, Douglas, Homeyra   +2 more
openaire   +2 more sources

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto, Lucia Buccarello, Giuseppe Carota, Rocco Salvatore Calabrò, Carmela Rifici, Emanuela Esposito, Alessio Ardizzone, Giuseppe Caruso   +7 more
wiley   +1 more source

Pernicious Anemia and Helicobacter pylori Infection: What a Hematologist Needs to Know?

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Helicobacter pylori infection and the possible underlying mechanism of parietal cell damage, and progression to pernicious anemia. ABSTRACT This case report emphasizes the importance of early detection and prompt treatment of Helicobacter pylori (H. pylori) as a reversible cause of autoimmune gastritis and its associated vitamin B‐12 deficiency.
Eisha Saadat, Mohammad Shahzaib Qadir, Bushra Moiz   +2 more
wiley   +1 more source

MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia

Brain Sciences, 2019
The incidence of dementia is on the rise and expected to continue to increase in the foreseeable future. Two of the most common subtypes of dementia are Alzheimer’s subtype and vascular dementia.
Christian E. Cajavilca, Rajan R. Gadhia, Gustavo C. Román   +2 more
doaj   +1 more source